Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing.Yu G., Nishimura M., Arawaka S., Levitan D., Zhang L., Tandon A., Song Y.-Q., Rogaeva E., Chen F.[...], St George-Hyslop P.H.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 407:48-54 (2000)Cited in4Mapped to10
The genome sequence of Drosophila melanogaster.Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A.[...], Venter J.C.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainBerkeleyCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 287:2185-2195 (2000)Cited in99+99+Mapped to9
Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H.[...], Lewis S.E.View abstractCited forGENOME REANNOTATIONStrainBerkeleyCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Biol. 3:RESEARCH0083.1-RESEARCH0083.22 (2002)Cited in99+99+Mapped to25
No title available.Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J.W., Champe M., Chavez C., Dorsett V., Dresnek D.[...], Celniker S.E.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]StrainBerkeleyTissueEmbryoCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (JAN-2003)Cited in42
Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila.Chung H.-M., Struhl G.View abstractCited forFUNCTION IN NOTCH SIGNALINGCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Cell Biol. 3:1129-1132 (2001)Cited in1Mapped to24
Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor.Hu Y., Ye Y., Fortini M.E.View abstractCited forFUNCTION IN THE GAMMA-SECRETASE COMPLEXCategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCDev. Cell 2:69-78 (2002)Cited in1Mapped to23
Drosophila nicastrin is essential for the intramembranous cleavage of notch.Lopez-Schier H., St Johnston D.View abstractCited forFUNCTION IN NOTCH SIGNALINGCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCDev. Cell 2:79-89 (2002)Cited in1Mapped to46
The role of presenilin cofactors in the gamma-secretase complex.Takasugi N., Tomita T., Hayashi I., Tsuruoka M., Niimura M., Takahashi Y., Thinakaran G., Iwatsubo T.View abstractCited forFUNCTION IN THE GAMMA-SECRETASE COMPLEX, INTERACTION WITH PSN; PEN-2 AND APH-1CategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 422:438-441 (2003)Cited in4Mapped to17
Human Diseases Associated with Notch Signalling: Lessons from <i>Drosophila melanogaster</i>.Megaly M., Turgambayeva A., Hallam R.D., Foran G., Megaly M., Necakov A.View abstractSourceFlyBase: FBgn0039234PubMedEurope PMCFront Biosci (Landmark Ed) 29:234-234 (2024)Mapped to99+
Box-Behnken Design-Based Optimization of Phytochemical Extraction from <i>Diplazium esculentum</i> (Retz.) Sw. Associated with Its Antioxidant and Anti-Alzheimer's Properties.Kongsung S., Inthachat W., Chantong B., Suttisansanee U., On-Nom N., Chupeerach C., Thangsiri S., Pitchakarn P., Temviriyanukul P.View abstractSourceFlyBase: FBgn0039234PubMedEurope PMCMolecules 29:2204-2204 (2024)Mapped to18
gamma-secretase promotes Drosophila postsynaptic development through the cleavage of a Wnt receptor.Restrepo L.J., DePew A.T., Moese E.R., Tymanskyj S.R., Parisi M.J., Aimino M.A., Duhart J.C., Fei H., Mosca T.J.View abstractCategoriesFunctionSourceFlyBase: FBgn0039234PubMedEurope PMCDev Cell 57:1643-1660.e7 (2022)Mapped to46
Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity.Kumar T., Blondel L., Extavour C.G.View abstractCategoriesFunctionSourceFlyBase: FBgn0039234PubMedEurope PMCElife 9:e54082-e54082 (2020)Mapped to99+
Neuronal immunoglobulin superfamily cell adhesion molecules in epithelial morphogenesis: insights from <i>Drosophila</i>.Finegan T.M., Bergstralh D.T.View abstractSourceFlyBase: FBgn0039234PubMedEurope PMCPhilos Trans R Soc Lond B Biol Sci 375:20190553-20190553 (2020)Mapped to99+
Post-Developmental Roles of Notch Signaling in the Nervous System.Salazar J.L., Yang S.A., Yamamoto S.View abstractSourceFlyBase: FBgn0039234PubMedEurope PMCBiomolecules 10:E985-E985 (2020)Mapped to49
CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 <i>Drosophila</i> genes conserved in humans.Wei P., Xue W., Zhao Y., Ning G., Wang J.View abstractCategoriesFunctionSourceFlyBase: FBgn0039234PubMedEurope PMCGenome Res 30:95-106 (2020)Mapped to99+
Notch and Delta are required for survival of the germline stem cell lineage in testes of Drosophila melanogaster.Ng C.L., Qian Y., Schulz C.View abstractCategoriesFunctionSourceFlyBase: FBgn0039234PubMedEurope PMCPLoS One 14:e0222471-e0222471 (2019)Mapped to38
Integration of Drosophila and Human Genetics to Understand Notch Signaling Related Diseases.Salazar J.L., Yamamoto S.View abstractSourceFlyBase: FBgn0039234PubMedEurope PMCAdv Exp Med Biol 1066:141-185 (2018)Mapped to99+
Serrate/Notch Signaling Regulates the Size of the Progenitor Cell Pool in <i>Drosophila</i> Imaginal Rings.Yang S.A., Deng W.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0039234PubMedEurope PMCGenetics 209:829-843 (2018)Mapped to31
Epsin-Dependent Ligand Endocytosis Activates Notch by Force.Langridge P.D., Struhl G.View abstractCategoriesFunction, InteractionSourceFlyBase: FBgn0039234PubMedEurope PMCCell 171:1383-1396.e12 (2017)Mapped to35
<i>Drosophila melanogaster</i>: Deciphering Alzheimer's Disease.Tan F.H.P., Azzam G.View abstractCategoriesFunctionSourceFlyBase: FBgn0039234PubMedEurope PMCMalays J Med Sci 24:6-20 (2017)Mapped to34
An Evolutionarily Conserved Role of Presenilin in Neuronal Protection in the Aging <i>Drosophila</i> Brain.Kang J., Shin S., Perrimon N., Shen J.View abstractAnnotationNct is required for neuronal survival during aging and normal lifespan.CategoriesPhenotypes & VariantsSourceFlyBase: FBgn0039234, GeneRif: 42964PubMedEurope PMCGenetics 206:1479-1493 (2017)Mapped to8
Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes.Phanse S., Wan C., Borgeson B., Tu F., Drew K., Clark G., Xiong X., Kagan O., Kwan J.[...], Emili A.View abstractCategoriesFunction, InteractionSourceFlyBase: FBgn0039234PubMedEurope PMCData Brief 6:715-721 (2016)Mapped to99+
SUMO-Enriched Proteome for Drosophila Innate Immune Response.Handu M., Kaduskar B., Ravindranathan R., Soory A., Giri R., Elango V.B., Gowda H., Ratnaparkhi G.S.View abstractCategoriesPTM / ProcessingSourceFlyBase: FBgn0039234PubMedEurope PMCG3 (Bethesda) 5:2137-2154 (2015)Mapped to99+
Genome-wide RNAi screen identifies networks involved in intestinal stem cell regulation in Drosophila.Zeng X., Han L., Singh S.R., Liu H., Neumuller R.A., Yan D., Hu Y., Liu Y., Liu W.[...], Hou S.X.View abstractCategoriesFunctionSourceFlyBase: FBgn0039234PubMedEurope PMCCell Rep 10:1226-1238 (2015)Mapped to99+
A re-examination of the selection of the sensory organ precursor of the bristle sensilla of Drosophila melanogaster.Troost T., Schneider M., Klein T.View abstractCategoriesFunctionSourceFlyBase: FBgn0039234PubMedEurope PMCPLoS Genet 11:e1004911-e1004911 (2015)Mapped to41