Q9V7U0 · RESIL_DROME
- ProteinPro-resilin
- Generesilin
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids620 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Plays a central role in insect flight by providing low stiffness, high strain and efficient energy storage.
Biotechnology
Its strong elasticity suggests that it may be used for industrial and pharmaceutical applications. Recombinant protein can be cast into a rubber-like biomaterial by rapid photochemical cross-linking. The resilience (recovery after deformation) of cross-linked recombinant resilin exceeds that of unfilled synthetic polybutadiene, a high resilience rubber.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chitin-based extracellular matrix | |
Cellular Component | extracellular matrix | |
Cellular Component | extracellular region | |
Cellular Component | protein-carbohydrate complex | |
Molecular Function | chitin binding | |
Molecular Function | extracellular matrix constituent conferring elasticity | |
Molecular Function | structural constituent of chitin-based larval cuticle | |
Molecular Function | structural constituent of cuticle | |
Biological Process | chitin-based cuticle development |
Names & Taxonomy
Protein names
- Recommended namePro-resilin
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ9V7U0
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
Keywords
- Cellular component
Phenotypes & Variants
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-17 | |||||
Sequence: MFKLLGLTLLMAMVVLG | ||||||
Chain | PRO_0000042845 | 18-620 | Pro-resilin | |||
Sequence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|
Proteomic databases
Expression
Structure
Family & Domains
Features
Showing features for region, repeat, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 22-376 | Disordered | ||||
Sequence: PVNSYLPPSDSYGAPGQSGPGGRPSDSYGAPGGGNGGRPSDSYGAPGQGQGQGQGQGGYAGKPSDTYGAPGGGNGNGGRPSSSYGAPGGGNGGRPSDTYGAPGGGNGGRPSDTYGAPGGGGNGNGGRPSSSYGAPGQGQGNGNGGRSSSSYGAPGGGNGGRPSDTYGAPGGGNGGRPSDTYGAPGGGNNGGRPSSSYGAPGGGNGGRPSDTYGAPGGGNGNGSGGRPSSSYGAPGQGQGGFGGRPSDSYGAPGQNQKPSDSYGAPGSGNGNGGRPSSSYGAPGSGPGGRPSDSYGPPASGSGAGGAGGSGPGGADYDNDEPAKYEFNYQVEDAPSGLSFGHSEMRDGDFTTGQYN | ||||||
Repeat | 42-56 | Elastic 1 | ||||
Sequence: GGRPSDSYGAPGGGN | ||||||
Repeat | 57-77 | Elastic 2 | ||||
Sequence: GGRPSDSYGAPGQGQGQGQGQ | ||||||
Compositional bias | 66-80 | Polar residues | ||||
Sequence: APGQGQGQGQGQGGY | ||||||
Repeat | 78-97 | Elastic 3 | ||||
Sequence: GGYAGKPSDTYGAPGGGNGN | ||||||
Repeat | 98-112 | Elastic 4 | ||||
Sequence: GGRPSSSYGAPGGGN | ||||||
Repeat | 113-127 | Elastic 5 | ||||
Sequence: GGRPSDTYGAPGGGN | ||||||
Repeat | 128-145 | Elastic 6 | ||||
Sequence: GGRPSDTYGAPGGGGNGN | ||||||
Compositional bias | 145-175 | Polar residues | ||||
Sequence: NGGRPSSSYGAPGQGQGNGNGGRSSSSYGAP | ||||||
Repeat | 146-164 | Elastic 7 | ||||
Sequence: GGRPSSSYGAPGQGQGNGN | ||||||
Repeat | 165-179 | Elastic 8 | ||||
Sequence: GGRSSSSYGAPGGGN | ||||||
Repeat | 180-194 | Elastic 9 | ||||
Sequence: GGRPSDTYGAPGGGN | ||||||
Repeat | 195-210 | Elastic 10 | ||||
Sequence: GGRPSDTYGAPGGGNN | ||||||
Repeat | 211-225 | Elastic 11 | ||||
Sequence: GGRPSSSYGAPGGGN | ||||||
Repeat | 226-244 | Elastic 12 | ||||
Sequence: GGRPSDTYGAPGGGNGNGS | ||||||
Repeat | 245-262 | Elastic 13 | ||||
Sequence: GGRPSSSYGAPGQGQGGF | ||||||
Repeat | 263-276 | Elastic 14 | ||||
Sequence: GGRPSDSYGAPGQN | ||||||
Compositional bias | 270-299 | Polar residues | ||||
Sequence: YGAPGQNQKPSDSYGAPGSGNGNGGRPSSS | ||||||
Repeat | 277-292 | Elastic 15 | ||||
Sequence: QKPSDSYGAPGSGNGN | ||||||
Repeat | 293-307 | Elastic 16 | ||||
Sequence: GGRPSSSYGAPGSGP | ||||||
Repeat | 308-324 | Elastic 17 | ||||
Sequence: GGRPSDSYGPPASGSGA | ||||||
Domain | 342-415 | Chitin-binding type R&R | ||||
Sequence: PAKYEFNYQVEDAPSGLSFGHSEMRDGDFTTGQYNVLLPDGRKQIVEYEADQQGYRPQIRYEGDANDGSGPSGP | ||||||
Region | 390-620 | Disordered | ||||
Sequence: EADQQGYRPQIRYEGDANDGSGPSGPGGPGGQNLGADGYSSGRPGNGNGNGNGGYSGGRPGGQDLGPSGYSGGRPGGQDLGAGGYSNGKPGGQDLGPGGYSGGRPGGQDLGRDGYSGGRPGGQDLGASGYSNGRPGGNGNGGSDGGRVIIGGRVIGGQDGGDQGYSGGRPGGQDLGRDGYSSGRPGGRPGGNGQDSQDGQGYSSGRPGQGGRNGFGPGGQNGDNDGSGYRY | ||||||
Compositional bias | 582-596 | Polar residues | ||||
Sequence: GQDSQDGQGYSSGRP |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence & Isoform
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
This entry describes 2 isoforms produced by Alternative splicing.
Q9V7U0-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- NameA
- Length620
- Mass (Da)58,604
- Last updated2000-05-01 v1
- Checksum432AFA06E54CB6BA
Q9V7U0-2
- NameB
- Differences from canonical
- 341-385: Missing
Features
Showing features for compositional bias, alternative sequence.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 66-80 | Polar residues | ||||
Sequence: APGQGQGQGQGQGGY | ||||||
Compositional bias | 145-175 | Polar residues | ||||
Sequence: NGGRPSSSYGAPGQGQGNGNGGRSSSSYGAP | ||||||
Compositional bias | 270-299 | Polar residues | ||||
Sequence: YGAPGQNQKPSDSYGAPGSGNGNGGRPSSS | ||||||
Alternative sequence | VSP_051872 | 341-385 | in isoform B | |||
Sequence: Missing | ||||||
Compositional bias | 582-596 | Polar residues | ||||
Sequence: GQDSQDGQGYSSGRP |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE013599 EMBL· GenBank· DDBJ | AAF57953.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE013599 EMBL· GenBank· DDBJ | AAS64829.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT003322 EMBL· GenBank· DDBJ | AAO25082.1 EMBL· GenBank· DDBJ | mRNA |