Q9V1I3 · LYSK_PYRAB

Function

function

Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Co2+ (UniProtKB | Rhea| CHEBI:48828 )

Note: Binds 2 Zn2+ or Co2+ ions per subunit.

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (Thermus route): step 5/5.
Amino-acid biosynthesis; L-arginine biosynthesis.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site67Zn2+ 1 (UniProtKB | ChEBI)
Active site69
Binding site91Zn2+ 1 (UniProtKB | ChEBI)
Binding site91Zn2+ 2 (UniProtKB | ChEBI)
Active site118Proton acceptor
Binding site119Zn2+ 2 (UniProtKB | ChEBI)
Binding site140Zn2+ 1 (UniProtKB | ChEBI)
Binding site298Zn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncobalt ion binding
Molecular Functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Molecular Functionzinc ion binding
Biological Processarginine biosynthetic process via ornithine
Biological Processlysine biosynthetic process via aminoadipic acid

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative [LysW]-lysine/[LysW]-ornithine hydrolase
  • EC number

Gene names

    • Name
      lysK
    • ORF names
      PAB0294
    • Ordered locus names
      PYRAB04440

Organism names

Accessions

  • Primary accession
    Q9V1I3
  • Secondary accessions
    • G8ZGE7

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001853451-337Putative [LysW]-lysine/[LysW]-ornithine hydrolase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the peptidase M20A family. LysK subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    337
  • Mass (Da)
    37,448
  • Last updated
    2000-05-01 v1
  • Checksum
    B082B30C55C524CB
MEIPKDEKIKFLKELVEIYSPTGKEEEAAKFIKEKLEEYGVKAYIDKVGNVIGVKEGEGPLILLAGHVDTVPGYIPVRIEGDILWGRGSVDAKGPLSALLFAMVESNANVIFAGLVDEEGFSKGARALDVPRPEYVIVGEPSGVNGVTIGYKGSLTVRFVERVEKFHGSIGGGAAEKLIERWLSISGNFEDGFNGLSGRIVRFVAYERDFEFYGEMIVNLRTPPGYEPPRDWDIIDFVPAYEVNRRSPLVRTFVRSIRELGMKPKLKKKSGTADMNILAPRFGVDAVAYGPGDSRLDHTPYERISLMEYLQSIDVLKNVLTKLKGKDLDKIYKSSPR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ248284
EMBL· GenBank· DDBJ
CAB49366.1
EMBL· GenBank· DDBJ
Genomic DNA
HE613800
EMBL· GenBank· DDBJ
CCE69826.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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