Q9V0N0 · PANE_PYRAB

Function

function

Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid.

Catalytic activity

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site7-12NADP+ (UniProtKB | ChEBI)
Binding site74NADP+ (UniProtKB | ChEBI)
Binding site99NADP+ (UniProtKB | ChEBI)
Binding site123NADP+ (UniProtKB | ChEBI)
Active site179Proton donor
Binding site179substrate
Binding site183substrate
Binding site187substrate
Binding site197substrate
Binding site246-249substrate
Binding site261NADP+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function2-dehydropantoate 2-reductase activity
Biological Processcoenzyme A biosynthetic process
Biological Processpantothenate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    2-dehydropantoate 2-reductase
  • EC number
  • Alternative names
    • Ketopantoate reductase
      (KPR
      )

Gene names

    • Name
      apbA
    • ORF names
      PAB0512
    • Ordered locus names
      PYRAB07590

Organism names

Accessions

  • Primary accession
    Q9V0N0
  • Secondary accessions
    • G8ZGW0

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001573251-3002-dehydropantoate 2-reductase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the ketopantoate reductase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    300
  • Mass (Da)
    32,773
  • Last updated
    2000-05-01 v1
  • Checksum
    F559625B73F691DC
MKIYILGAGAIGSLFGGLLANAGEDVLLIGRDPHVSAINEKGLKIVGIKDLNVKVEATTRVPEEKPDLIVLATKSYSTIEALKSARHIVKGSWVLSIQNGIGNEDKIIEFGGKAIGGITTNGAMVEAPGVIKWTGKGVTIIGLYPQGKEKFIEKVADVFNSADIETHVSENIISWIWAKAIVNSAINPIGTLLEVKNKVIRENDFLLSMAMEVVKEGCRVALQNGIEFDVPPMDLFFQTLEQTRENYNSMLQDIWRGKKTEVDYINGKIVEYAKAVNLEAPMNLLLWGLIKGKEALEGKK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ248285
EMBL· GenBank· DDBJ
CAB49673.1
EMBL· GenBank· DDBJ
Genomic DNA
HE613800
EMBL· GenBank· DDBJ
CCE70155.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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