Prediction of factor VIII inhibitor development in the SIPPET cohort by mutational analysis and factor VIII antigen measurement.
- AnnotationThe type of F8 mutation is the main predictor of inhibitor development in patients with severe hemophilia A. Findings confirm an association between the synthesis of minute amounts of FVIII and inhibitor protection.
- CategoriesSequences, Disease & Variants
- SourceGeneRif: 2157