Four new members expand the IL-1 superfamily.Smith D.E., Renshaw B.R., Ketchem R.R., Kubin M., Garka K.E., Sims J.E.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]TissuePlacentaCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 275:1169-1175 (2000)Cited in41Mapped to7
IL1HY1: a novel interleukin-1 receptor antagonist gene.Mulero J.J., Pace A.M., Nelken S.T., Loeb D.B., Correa T.R., Drmanac R., Ford J.E.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]TissueFetal skinCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochem. Biophys. Res. Commun. 263:702-706 (1999)Cited in11Mapped to4
A tissue specific IL-1 receptor antagonist homolog from the IL-1 cluster lacks IL-1, IL-1ra, IL-18 and IL-18 antagonist activities.Barton J.L., Herbst R., Bosisio D., Higgins L., Nicklin M.J.H.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]TissuePlacentaCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEur. J. Immunol. 30:3299-3308 (2000)Cited in22
Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2.Debets R., Timans J.C., Homey B., Zurawski S., Sana T.R., Lo S., Wagner J., Edwards G., Clifford T.[...], Kastelein R.A.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITYCategoriesFunction, Sequences, ExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Immunol. 167:1440-1446 (2001)Cited in61Mapped to1
Identification and gene organization of three novel members of the IL-1 family on human chromosome 2.Busfield S.J., Comrack C.A., Yu G., Chickering T.W., Smutko J.S., Zhou H., Leiby K.R., Holmgren L.M., Gearing D.P., Pan Y.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenomics 66:213-216 (2000)Cited in21
A sequence-based map of the nine genes of the human interleukin-1 cluster.Nicklin M.J.H., Barton J.L., Nguyen M., Fitzgerald M.G., Duff W.G., Kornman K.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenomics 79:718-725 (2002)Cited in81
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C.[...], Gray A.M.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 13:2265-2270 (2003)Cited in99+84
Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H.[...], Sugano S.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]TissueCervixCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Genet. 36:40-45 (2004)Cited in99+99+
No title available.SeattleSNPs variation discovery resourceCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANT SER-47CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (MAR-2005)Cited in6
Generation and annotation of the DNA sequences of human chromosomes 2 and 4.Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K.[...], Wilson R.K.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 434:724-731 (2005)Cited in99+99+
No title available.Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H.[...], Venter J.C.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (JUL-2005)Cited in99+
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]TissuePlacentaCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
Interleukin-36 (IL-36) ligands require processing for full agonist (IL- 36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity.Towne J.E., Renshaw B.R., Douangpanya J., Lipsky B.P., Shen M., Gabel C.A., Sims J.E.View abstractCited forFUNCTION, CLEAVAGE OF INITIATOR METHIONINECategoriesFunction, PTM / ProcessingSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 286:42594-42602 (2011)Cited in10Mapped to5
The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses.Gresnigt M.S., Roesler B., Jacobs C.W., Becker K.L., Joosten L.A., van der Meer J.W., Netea M.G., Dinarello C.A., van de Veerdonk F.L.View abstractCited forFUNCTION, INDUCTIONCategoriesFunction, ExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEur. J. Immunol. 43:416-426 (2013)Cited in2
A Translocation Pathway for Vesicle-Mediated Unconventional Protein Secretion.Zhang M., Liu L., Lin X., Wang Y., Li Y., Guo Q., Li S., Sun Y., Tao X.[...], Ge L.View abstractCited forSUBCELLULAR LOCATION, INTERACTION WITH TMED10CategoriesInteraction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 181:637-652 (2020)Cited in19Mapped to1
Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis.Onoufriadis A., Simpson M.A., Pink A.E., Di Meglio P., Smith C.H., Pullabhatla V., Knight J., Spain S.L., Nestle F.O.[...], Barker J.N.View abstractCited forVARIANTS PSORS14 TRP-48 AND LEU-113CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCAm. J. Hum. Genet. 89:432-437 (2011)Cited in1
Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis.Marrakchi S., Guigue P., Renshaw B.R., Puel A., Pei X.Y., Fraitag S., Zribi J., Bal E., Cluzeau C.[...], Smahi A.View abstractCited forVARIANT PSORS14 PRO-27, CHARACTERIZATION OF VARIANT PSORS14 PRO-27CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCN. Engl. J. Med. 365:620-628 (2011)Cited in1Mapped to2
Mutation analysis of the IL36RN gene in 14 Japanese patients with generalized pustular psoriasis.Farooq M., Nakai H., Fujimoto A., Fujikawa H., Matsuyama A., Kariya N., Aizawa A., Fujiwara H., Ito M., Shimomura Y.View abstractCited forVARIANT PSORS14 ARG-123, CHARACTERIZATION OF VARIANT PSORS14 ARG-123CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCHum. Mutat. 34:176-183 (2013)Cited in1
In Silico and In Vitro Analysis of IL36RN Alterations Reveals Critical Residues for the Function of the Interleukin-36 Receptor Complex.Hassi N.K., Weston T., Rinaldi G., Ng J.C., Smahi A., Twelves S., Davan-Wetton C., Fakhreddine D., Fraternali F., Capon F.View abstractAnnotationIn Silico and In Vitro Analysis of IL36RN Alterations Reveals Critical Residues for the Function of the Interleukin-36 Receptor Complex.SourceGeneRif: 26525PubMedEurope PMCJ Invest Dermatol 143:2468-2475.e6 (2023)Mapped to3
Deficiency of interleukin-36 receptor antagonist (DITRA): An analysis of 58 Chinese patients in a tertiary hospital in Taiwan.Hsieh C.Y., Huang Y.W., Huang Y.H., Tsai T.F.View abstractAnnotationDeficiency of interleukin-36 receptor antagonist (DITRA): An analysis of 58 Chinese patients in a tertiary hospital in Taiwan.SourceGeneRif: 26525PubMedEurope PMCExp Dermatol 32:1272-1278 (2023)Mapped to1
Clinical profile of patients with acute generalized pustular psoriasis with and without IL36RN mutations in multi-ethnic Johor Bahru, Malaysia.Choon S.E., Tok P.S.K., Wong K.W., Lim Y.T., Nanu N.M., Barker J.N., Capon F.View abstractAnnotationClinical profile of patients with acute generalized pustular psoriasis with and without IL36RN mutations in multi-ethnic Johor Bahru Malaysia.SourceGeneRif: 26525PubMedEurope PMCExp Dermatol 32:1263-1271 (2023)Mapped to1
Identification of the BTN3A3 Gene as a Molecule Implicated in Generalized Pustular Psoriasis in a Chinese Population.Zhang Q., Shi P., Wang Z., Sun L., Li W., Zhao Q., Liu T., Pan Q., Sun Y.[...], Zhang F.View abstractAnnotationIdentification of the BTN3A3 Gene as a Molecule Implicated in Generalized Pustular Psoriasis in a Chinese Population.SourceGeneRif: 26525PubMedEurope PMCJ Invest Dermatol 143:1439-1448.e21 (2023)Mapped to99+
Different Clinical Features of Pediatric Generalized Pustular Psoriasis in Patients with or without IL36RN Variants.Wang Z., Xiang X., Chen Y., Qi Z., Miao C., Liu Y., Zhao X., Zhang Y., Zhang Z.[...], Ma L.View abstractAnnotationDifferent Clinical Features of Pediatric Generalized Pustular Psoriasis in Patients with or without IL36RN Variants.CategoriesSequencesSourceGeneRif: 26525PubMedEurope PMCDermatology 239:217-226 (2023)Mapped to1
Correlation of IL36RN and CARD14 mutations with clinical manifestations and laboratory findings in patients with generalised pustular psoriasis.Trai N.N., Van Em D., Van B.T., My L.H., Van Tro C., Hao N.T., Vu H.A., Tram D.B., Van Thuong N., Doanh L.H.View abstractAnnotationCorrelation of IL36RN and CARD14 mutations with clinical manifestations and laboratory findings in patients with generalised pustular psoriasis.CategoriesSequencesSourceGeneRif: 26525PubMedEurope PMCIndian J Dermatol Venereol Leprol 89:378-384 (2023)Mapped to4
IL-36 Cytokines: Their Roles in Asthma and Potential as a Therapeutic.Dong H., Hao Y., Li W., Yang W., Gao P.View abstractAnnotationIL-36 Cytokines: Their Roles in Asthma and Potential as a Therapeutic.CategoriesFunctionSourceGeneRif: 26525PubMedEurope PMCFront Immunol 13:921275-921275 (2022)Mapped to4