Q9U5E0 · Q9U5E0_DROME

Function

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchromosome
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular Function3'-5' DNA helicase activity
Molecular FunctionATP binding
Molecular FunctionDNA helicase activity
Molecular Functionfour-way junction helicase activity
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionnucleic acid binding
Molecular Functionsingle-stranded DNA helicase activity
Biological ProcessDNA damage response
Biological ProcessDNA unwinding involved in DNA replication
Biological Processdouble-strand break repair via homologous recombination
Biological Processdouble-strand break repair via single-strand annealing
Biological Processmitotic sister chromatid segregation
Biological Processnegative regulation of mitotic cell cycle
Biological Processregulation of DNA-templated transcription
Biological Processresponse to X-ray

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA 3'-5' helicase
  • EC number

Gene names

    • Name
      RecQ5
    • Synonyms
      RECQE
    • ORF names
      CG4879

Organism names

  • Taxonomic identifier
  • Strain
    • Canton S
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    Q9U5E0

Organism-specific databases

Subcellular Location

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain30-205Helicase ATP-binding
Domain244-394Helicase C-terminal
Region479-504Disordered
Compositional bias668-689Basic and acidic residues
Region668-805Disordered
Compositional bias699-750Basic and acidic residues
Compositional bias777-802Basic and acidic residues
Region854-887Disordered
Compositional bias872-887Basic and acidic residues
Region916-984Disordered

Sequence similarities

Belongs to the helicase family. RecQ subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,058
  • Mass (Da)
    121,116
  • Last updated
    2000-05-01 v1
  • MD5 Checksum
    FB3BAA47ECD4B24A04786EA24FF1FE52
MAHESAVHEALKKHFGHSKFKSDLQEKAVKCAVKKKQDVYVSMPTGSGKSLCFQLPGLMSENQITIVFSPLLALIKDQIDHLTKLKVPADSLNSKMSTKERDRVIMDLKAVRTNLKFLYITPEQAATKFFQDLLQTLHKHNKLAYFAVDEAHCVSQWGHDFRPDYLKLGELRSKYSDVIWLALTATASREVKEDIYKQLRLHQPVAQFSTPSFRKNLFYDIVYKNSIEDDFQHLADFARHCLGNPKEFKDTPKPQRGCGIVYCRTRDQVERMAIGVTKQGIGAVAYHAGLKTGERTEVQEAWMRGDQPIICATNSFGMGVDKPSVRFVIHWDVPQNVAAYYQESGRAGRDGLQSYCRLYYGREDVRSIRFLLQNDAHRARGRGDKELLTERAIKQFEKITEFCERTTCRHKLFSDFFGDPTPDCSGQCDVCKRPKKADKALEMFHRLCMDDAFKSHISLQDCADLYEGGRPGIKRAAQEYAGGESGSDDDSGQSHSSMAKRAKKESQDFIKQQFNLRKQISAARQLEQETIAQISRVRMAEATEKKIAGLQATHREKYLTALIDALKANVDKCKDEPGQQPKSVLKYNDYEAMSVNMEYDVFRQNKVANMYRHALVKEISTIKKLTEQTKLLPLLVDYIPKPETSSKGAWTGGSVAYFERKLKELEEQRPQSLKEVPKALKDRKGFKQENSKQTSISSFFKKEIKEEPIDSPIQEERVNIKSEQMDLEESTPKDIASNHVKEESVTPESSSSDRELELQPDSIIGERKFKLMSNGDGSYDTHRRKRVSHETQPKEKESIKTKSSMQHLFGSFKSESEESNQSLNCFKTARQMLEENNAKLKGVPEKLPIKDGEKGVLENRADSIGFTSAREMLERSKQREGDDKSSNKLEKLGFISAREMLEKNKLNERCLDKKDVKEKKLESRETKRSLQNNELQHKQEEDRKDKASHRKTSKESLSNLKKEGSDSRALQKDTKPETRNHQKTDVSKNVVQWLNPYYKRKIATKELFKALAKLLTQRICDGSLGDGDAGKCYIKETFHGLHMINNDQDIEKYFIKSK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias668-689Basic and acidic residues
Compositional bias699-750Basic and acidic residues
Compositional bias777-802Basic and acidic residues
Compositional bias872-887Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB031086
EMBL· GenBank· DDBJ
BAA88312.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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