Q9U4I2 · Q9U4I2_DROME
- ProteinSANT domain protein SMRTER
- GeneSmr
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids3469 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chromatin | |
Cellular Component | cytosol | |
Cellular Component | nucleoplasm | |
Cellular Component | polytene chromosome | |
Cellular Component | transcription repressor complex | |
Molecular Function | chromatin binding | |
Molecular Function | transcription corepressor activity | |
Biological Process | follicle cell of egg chamber development | |
Biological Process | regulation of mitotic cell cycle | |
Biological Process | regulation of transcription by RNA polymerase II |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ9U4I2
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, coiled coil, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 56-81 | Disordered | ||||
Sequence: KQAAHLQQQQHQSHQQQQQQQQDQRT | ||||||
Compositional bias | 110-128 | Polar residues | ||||
Sequence: QQQQQKQQQHHMQQQQQQQ | ||||||
Region | 110-145 | Disordered | ||||
Sequence: QQQQQKQQQHHMQQQQQQQPLSPPHPPGSSSNSSSA | ||||||
Region | 160-218 | Disordered | ||||
Sequence: NPGYPPSSAAAAAVNSGYPPRPPQHRFIQNTGYSIAPAPTYRDNPYSRHTQIQQQQQQQ | ||||||
Compositional bias | 203-218 | Polar residues | ||||
Sequence: NPYSRHTQIQQQQQQQ | ||||||
Compositional bias | 259-279 | Polar residues | ||||
Sequence: KGNVSGQSSNSSSSSSGGGGG | ||||||
Region | 259-296 | Disordered | ||||
Sequence: KGNVSGQSSNSSSSSSGGGGGGGSAGGSAPPGGGVVQV | ||||||
Compositional bias | 311-338 | Polar residues | ||||
Sequence: YASQPNSNPSQQQQQQQQQQQGGNPSGA | ||||||
Region | 311-353 | Disordered | ||||
Sequence: YASQPNSNPSQQQQQQQQQQQGGNPSGAGATSGAGGGGGGSGG | ||||||
Compositional bias | 396-410 | Polar residues | ||||
Sequence: LQLQQQQQQQHPPEP | ||||||
Region | 396-475 | Disordered | ||||
Sequence: LQLQQQQQQQHPPEPFGGQQPYKKQRLSEANANNMNHLPPHPQQQHQQQQQQQQQHQRSSPAQVQQQQQQQMNSSRQSHN | ||||||
Compositional bias | 419-475 | Polar residues | ||||
Sequence: KQRLSEANANNMNHLPPHPQQQHQQQQQQQQQHQRSSPAQVQQQQQQQMNSSRQSHN | ||||||
Region | 494-527 | Disordered | ||||
Sequence: TLPQQQQKQQQHQQQQQQQQQGRSQPVVSSMSTV | ||||||
Region | 543-568 | Disordered | ||||
Sequence: SASHSGSSGNVAAGLGTGNTGSASTE | ||||||
Coiled coil | 596-637 | |||||
Sequence: KEDLLMQIQKVDNEIKSAETTMETLRKKEKSLMEEAALAKEQ | ||||||
Domain | 866-917 | SANT | ||||
Sequence: KALNMWTAGEKETFKEKYLQHPKNFGAIAASLDRKSPQDCVRYYYLSKKTEN | ||||||
Region | 920-946 | Disordered | ||||
Sequence: QLLRKSRQRTRSSRNPAKAQAAQPQCI | ||||||
Compositional bias | 932-946 | Polar residues | ||||
Sequence: SRNPAKAQAAQPQCI | ||||||
Region | 958-990 | Disordered | ||||
Sequence: LQREQQQKSGGRSSAVAERERAERAAERERVAE | ||||||
Compositional bias | 971-990 | Basic and acidic residues | ||||
Sequence: SAVAERERAERAAERERVAE | ||||||
Region | 1037-1068 | Disordered | ||||
Sequence: TATTATTTTSSSTSSSSSSASSASTASSSTAS | ||||||
Compositional bias | 1086-1116 | Polar residues | ||||
Sequence: ASASDKNAATAGGPTATGTPTAATTPATATA | ||||||
Region | 1086-1141 | Disordered | ||||
Sequence: ASASDKNAATAGGPTATGTPTAATTPATATAPPEISAGGEAKSKNAEEEAAATAGA | ||||||
Region | 1171-1204 | Disordered | ||||
Sequence: TAAAKGVGKPETATEPAGTAAKGADSRPDANDPL | ||||||
Region | 1291-1319 | Disordered | ||||
Sequence: DKIVKTTPSSRAPNSTSSTAANESSSGAG | ||||||
Region | 1365-1389 | Disordered | ||||
Sequence: ELNSGEAGGNATSAMTNSSTSGSMN | ||||||
Compositional bias | 1370-1389 | Polar residues | ||||
Sequence: EAGGNATSAMTNSSTSGSMN | ||||||
Region | 1611-1834 | Disordered | ||||
Sequence: QLNLTDGSSGGAGSGSGGDETDVSTSSCDEREPGGSDTASVESPENLQRHKSLTMVKQQQQQQQQQQQQQQQQQQQQQQQLSQPQPPPPAPQQQKGSSGRGGDQGTPLIITPTRMSSKSGSGGAQTAGDNERLLPPAAGQAPKKQKTSEEYDSSATETADEENENSPANRQSPKVLFHGHGHGHGGHANNVAGLQPPVANMGTGGGVQPGGAAGQQVNGPISMR | ||||||
Compositional bias | 1612-1691 | Polar residues | ||||
Sequence: LNLTDGSSGGAGSGSGGDETDVSTSSCDEREPGGSDTASVESPENLQRHKSLTMVKQQQQQQQQQQQQQQQQQQQQQQQL | ||||||
Compositional bias | 1719-1736 | Polar residues | ||||
Sequence: IITPTRMSSKSGSGGAQT | ||||||
Region | 1854-1905 | Disordered | ||||
Sequence: KHKGPQPKGGQGQQQGQGQGQGQGQGQTPGQSQSPSQQQQQQQQQQSANNLE | ||||||
Compositional bias | 1861-1905 | Polar residues | ||||
Sequence: KGGQGQQQGQGQGQGQGQGQTPGQSQSPSQQQQQQQQQQSANNLE | ||||||
Compositional bias | 1921-1954 | Polar residues | ||||
Sequence: ILKQQQQQQQAGGAPPTSAAGSLPHGTSVQKLTT | ||||||
Region | 1921-1979 | Disordered | ||||
Sequence: ILKQQQQQQQAGGAPPTSAAGSLPHGTSVQKLTTRPAAVAPPPPAHPLTPTSIGCAGSN | ||||||
Compositional bias | 2027-2052 | Polar residues | ||||
Sequence: VKSSSGSSKSGGGSASSHSTATPPET | ||||||
Region | 2027-2158 | Disordered | ||||
Sequence: VKSSSGSSKSGGGSASSHSTATPPETIIYNVPVAHPQRGIPPPSQHSVHPAHPSHTQHPAHPQHSSHGQHTQLQVPEPEPQTLDLSIKKPPRDGHSPHTGAGGSSSSGSGSGGPSSSDRHHGPPPPTMSMKH | ||||||
Compositional bias | 2084-2105 | Polar residues | ||||
Sequence: HPAHPQHSSHGQHTQLQVPEPE | ||||||
Compositional bias | 2125-2142 | Polar residues | ||||
Sequence: TGAGGSSSSGSGSGGPSS | ||||||
Region | 2226-2287 | Disordered | ||||
Sequence: QGQLPPKAGQPPPAQPPSGRGVAKVPPKLSPQQAHHLHPSHGHSPSQQQQQQQQQQQQQQQQ | ||||||
Compositional bias | 2231-2245 | Pro residues | ||||
Sequence: PKAGQPPPAQPPSGR | ||||||
Compositional bias | 2262-2287 | Polar residues | ||||
Sequence: LHPSHGHSPSQQQQQQQQQQQQQQQQ | ||||||
Region | 2335-2432 | Disordered | ||||
Sequence: FDGLVRQTTPEGVGSVGPGGASGSGKHGSITQGTPLHMPPHHLESKRPYESYYKSSQRHSPAQQPGGNQQLPPPPQQSSPQAPPPQGYGVGVSSPYAR | ||||||
Compositional bias | 2401-2416 | Pro residues | ||||
Sequence: GNQQLPPPPQQSSPQA | ||||||
Compositional bias | 2456-2486 | Polar residues | ||||
Sequence: ITSQQMQGQQQQQQQQQQQQRNMSRGSSASG | ||||||
Region | 2456-2653 | Disordered | ||||
Sequence: ITSQQMQGQQQQQQQQQQQQRNMSRGSSASGGGGGGGSDKESPSPRNSVGSASGFAYGGDKESAPRGRPEYSSRASPADHVNSTPSPHRTPPPQRQGVIQRHNTGSKPPSPAAPPPSRMHMPPYQYAPSGHDALASFVDVAVQQPQLPVPSQKDDKSPGPSTAPGQVPGSGPPLGPSPLPPHAVVGVAQPPPPTAHHD | ||||||
Compositional bias | 2563-2577 | Pro residues | ||||
Sequence: PPSPAAPPPSRMHMP | ||||||
Compositional bias | 2600-2614 | Polar residues | ||||
Sequence: PQLPVPSQKDDKSPG | ||||||
Compositional bias | 2620-2643 | Pro residues | ||||
Sequence: GQVPGSGPPLGPSPLPPHAVVGVA | ||||||
Region | 2693-2850 | Disordered | ||||
Sequence: QMDQAKRVMRHQQHQVQQQQQQQQQQQHNHALERDREMQERMRERDREREREREREQRERERERERERERERERREQDRARRVVAEEREHDSRRMERMFAGNVVTGSGGAGGGGPSPGQFLRASVPETGPPRSIPDRERESYYRQAHGGPAPEDTPGQ | ||||||
Compositional bias | 2703-2720 | Polar residues | ||||
Sequence: HQQHQVQQQQQQQQQQQH | ||||||
Compositional bias | 2721-2789 | Basic and acidic residues | ||||
Sequence: NHALERDREMQERMRERDREREREREREQRERERERERERERERERREQDRARRVVAEEREHDSRRMER | ||||||
Region | 2867-3005 | Disordered | ||||
Sequence: RSNDATAGPGREFPRPSFVHAPLPPRGSGSGGGTGTRSSPANVLHPMYLRDLRQPLDGGAGSMLTAENNGKPSSSGSPSVINIDLDQERISAAAAAVAQQQQQQQAPPPSQSSQSRSVHGQLRTPTSQSGGSAPSPQQI | ||||||
Compositional bias | 2932-2950 | Polar residues | ||||
Sequence: AENNGKPSSSGSPSVINID | ||||||
Compositional bias | 2960-3005 | Polar residues | ||||
Sequence: AAAVAQQQQQQQAPPPSQSSQSRSVHGQLRTPTSQSGGSAPSPQQI | ||||||
Region | 3050-3140 | Disordered | ||||
Sequence: WKQNRRMQQKAEEANDHSQQQQQQQHQQQHHAQQQQQQQQQHHAQQHHPQMPGTGSGSAPGGAGQGGGSGGPGSGGGGAGRASTPGEDGRN | ||||||
Compositional bias | 3063-3102 | Polar residues | ||||
Sequence: ANDHSQQQQQQQHQQQHHAQQQQQQQQQHHAQQHHPQMPG | ||||||
Region | 3184-3209 | Disordered | ||||
Sequence: PEQRGTPSGGGGAPGAGGPGSGGGAT | ||||||
Region | 3271-3324 | Disordered | ||||
Sequence: AMELQHRSKEPPPPEISVSRKTPNQYEVVDASGRRSAGSGSVSVSVSGANSHHS | ||||||
Compositional bias | 3306-3322 | Polar residues | ||||
Sequence: SAGSGSVSVSVSGANSH | ||||||
Region | 3415-3437 | Disordered | ||||
Sequence: GVPGGGGPGSGGGGGGGHNSSSS |
Sequence similarities
Belongs to the N-CoR nuclear receptor corepressors family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length3,469
- Mass (Da)364,116
- Last updated2000-05-01 v1
- Checksum6284E14C5C247CD9
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 110-128 | Polar residues | ||||
Sequence: QQQQQKQQQHHMQQQQQQQ | ||||||
Compositional bias | 203-218 | Polar residues | ||||
Sequence: NPYSRHTQIQQQQQQQ | ||||||
Compositional bias | 259-279 | Polar residues | ||||
Sequence: KGNVSGQSSNSSSSSSGGGGG | ||||||
Compositional bias | 311-338 | Polar residues | ||||
Sequence: YASQPNSNPSQQQQQQQQQQQGGNPSGA | ||||||
Compositional bias | 396-410 | Polar residues | ||||
Sequence: LQLQQQQQQQHPPEP | ||||||
Compositional bias | 419-475 | Polar residues | ||||
Sequence: KQRLSEANANNMNHLPPHPQQQHQQQQQQQQQHQRSSPAQVQQQQQQQMNSSRQSHN | ||||||
Compositional bias | 932-946 | Polar residues | ||||
Sequence: SRNPAKAQAAQPQCI | ||||||
Compositional bias | 971-990 | Basic and acidic residues | ||||
Sequence: SAVAERERAERAAERERVAE | ||||||
Compositional bias | 1086-1116 | Polar residues | ||||
Sequence: ASASDKNAATAGGPTATGTPTAATTPATATA | ||||||
Compositional bias | 1370-1389 | Polar residues | ||||
Sequence: EAGGNATSAMTNSSTSGSMN | ||||||
Compositional bias | 1612-1691 | Polar residues | ||||
Sequence: LNLTDGSSGGAGSGSGGDETDVSTSSCDEREPGGSDTASVESPENLQRHKSLTMVKQQQQQQQQQQQQQQQQQQQQQQQL | ||||||
Compositional bias | 1719-1736 | Polar residues | ||||
Sequence: IITPTRMSSKSGSGGAQT | ||||||
Compositional bias | 1861-1905 | Polar residues | ||||
Sequence: KGGQGQQQGQGQGQGQGQGQTPGQSQSPSQQQQQQQQQQSANNLE | ||||||
Compositional bias | 1921-1954 | Polar residues | ||||
Sequence: ILKQQQQQQQAGGAPPTSAAGSLPHGTSVQKLTT | ||||||
Compositional bias | 2027-2052 | Polar residues | ||||
Sequence: VKSSSGSSKSGGGSASSHSTATPPET | ||||||
Compositional bias | 2084-2105 | Polar residues | ||||
Sequence: HPAHPQHSSHGQHTQLQVPEPE | ||||||
Compositional bias | 2125-2142 | Polar residues | ||||
Sequence: TGAGGSSSSGSGSGGPSS | ||||||
Compositional bias | 2231-2245 | Pro residues | ||||
Sequence: PKAGQPPPAQPPSGR | ||||||
Compositional bias | 2262-2287 | Polar residues | ||||
Sequence: LHPSHGHSPSQQQQQQQQQQQQQQQQ | ||||||
Compositional bias | 2401-2416 | Pro residues | ||||
Sequence: GNQQLPPPPQQSSPQA | ||||||
Compositional bias | 2456-2486 | Polar residues | ||||
Sequence: ITSQQMQGQQQQQQQQQQQQRNMSRGSSASG | ||||||
Compositional bias | 2563-2577 | Pro residues | ||||
Sequence: PPSPAAPPPSRMHMP | ||||||
Compositional bias | 2600-2614 | Polar residues | ||||
Sequence: PQLPVPSQKDDKSPG | ||||||
Compositional bias | 2620-2643 | Pro residues | ||||
Sequence: GQVPGSGPPLGPSPLPPHAVVGVA | ||||||
Compositional bias | 2703-2720 | Polar residues | ||||
Sequence: HQQHQVQQQQQQQQQQQH | ||||||
Compositional bias | 2721-2789 | Basic and acidic residues | ||||
Sequence: NHALERDREMQERMRERDREREREREREQRERERERERERERERERREQDRARRVVAEEREHDSRRMER | ||||||
Compositional bias | 2932-2950 | Polar residues | ||||
Sequence: AENNGKPSSSGSPSVINID | ||||||
Compositional bias | 2960-3005 | Polar residues | ||||
Sequence: AAAVAQQQQQQQAPPPSQSSQSRSVHGQLRTPTSQSGGSAPSPQQI | ||||||
Compositional bias | 3063-3102 | Polar residues | ||||
Sequence: ANDHSQQQQQQQHQQQHHAQQQQQQQQQHHAQQHHPQMPG | ||||||
Compositional bias | 3306-3322 | Polar residues | ||||
Sequence: SAGSGSVSVSVSGANSH |