Q9TVY2 · Q9TVY2_ARTSF

Function

function

This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionP-type sodium:potassium-exchanging transporter activity
Biological Processintracellular potassium ion homeostasis
Biological Processintracellular sodium ion homeostasis
Biological Processpotassium ion import across plasma membrane
Biological Processproton transmembrane transport
Biological Processsodium ion export across plasma membrane

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Na(+)/K(+)-exchanging ATPase
  • EC number

Organism names

Accessions

  • Primary accession
    Q9TVY2

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane69-89Helical
Transmembrane104-123Helical
Transmembrane265-289Helical
Transmembrane295-318Helical

Keywords

  • Cellular component

Interaction

Subunit

The sodium/potassium-transporting ATPase is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit.

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain15-89Cation-transporting P-type ATPase N-terminal
Region190-209Disordered

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    454
  • Mass (Da)
    49,537
  • Last updated
    2000-05-01 v1
  • Checksum
    57D5D7BE5B59A13F
KGKDLNELKKELDIDFHKIPIEECYQRLGSNPETGLTNAQARSNIERDGPNCLTPPKTTPEWIKFCKNLFGGFALLLWTGAILCFLAYGIEASSGNEDMLKDNLYLGIVLATVVIVTGIFSYYQENKSSRIMDSFKNLVPQYALALREGQRVTLKAEELTMGDIVEVKFGDRVPADLRVLEARSFKVDNSSLTGESEPQARSPEFTNDNPLETKNLAFFSTNAVEGTMRGIVIGIGDNTVMGRIAGLASGLDTGETPIAKEIAHFIHIITGVAVFLGVTFFIIAFVLGYHWLDAVVFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDGTITEADTTEDQSGAQFDKSSAGWKALVKIAALCSRAEFKPNQSTTPILKREVTGDASEAAILKCVELTTGETEAIRKRNKKICEI

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue454

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ389864
EMBL· GenBank· DDBJ
CAB56395.1
EMBL· GenBank· DDBJ
mRNA
AJ389865
EMBL· GenBank· DDBJ
CAB56396.1
EMBL· GenBank· DDBJ
mRNA
AJ389866
EMBL· GenBank· DDBJ
CAB56397.1
EMBL· GenBank· DDBJ
mRNA
AJ389867
EMBL· GenBank· DDBJ
CAB56398.1
EMBL· GenBank· DDBJ
mRNA
AJ389868
EMBL· GenBank· DDBJ
CAB56399.1
EMBL· GenBank· DDBJ
mRNA
AJ389869
EMBL· GenBank· DDBJ
CAB56400.1
EMBL· GenBank· DDBJ
mRNA
AJ389870
EMBL· GenBank· DDBJ
CAB56401.1
EMBL· GenBank· DDBJ
mRNA
AJ389872
EMBL· GenBank· DDBJ
CAB56403.1
EMBL· GenBank· DDBJ
mRNA
AJ389873
EMBL· GenBank· DDBJ
CAB56404.1
EMBL· GenBank· DDBJ
mRNA
AJ389874
EMBL· GenBank· DDBJ
CAB56405.1
EMBL· GenBank· DDBJ
mRNA
AJ389876
EMBL· GenBank· DDBJ
CAB56407.1
EMBL· GenBank· DDBJ
mRNA
AJ389878
EMBL· GenBank· DDBJ
CAB56409.1
EMBL· GenBank· DDBJ
mRNA
AJ389881
EMBL· GenBank· DDBJ
CAB56412.1
EMBL· GenBank· DDBJ
mRNA
AJ389882
EMBL· GenBank· DDBJ
CAB56413.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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