Q9SZE4 · VP322_ARATH

Function

function

Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentESCRT III complex
Cellular Componentplasma membrane
Biological Processintralumenal vesicle formation
Biological Processprotein transport
Biological Processvacuolar transport

Keywords

Protein family/group databases

    • 3.A.31.1.2the endosomal sorting complexes required for transport iii (escrt-iii) family

Names & Taxonomy

Protein names

  • Recommended name
    Vacuolar protein sorting-associated protein 32 homolog 2
  • Short names
    AtVPS32-2
  • Alternative names
    • Charged multivesicular body protein 4 homolog 2
    • ESCRT-III complex subunit VPS32 homolog 2

Gene names

    • Name
      VPS32.2
    • Synonyms
      CHMP4-2, SNF7.1
      , SNF7B
    • ORF names
      F19B15.190
    • Ordered locus names
      At4g29160

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9SZE4
  • Secondary accessions
    • Q3E9U7
    • Q8L9C3

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003682011-219Vacuolar protein sorting-associated protein 32 homolog 2

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Subunit

Component of the endosomal sorting required for transport complex III (ESCRT-III), composed at least of VPS2, VPS20, VPS24 and VPS32 (By similarity).
Interacts with SKD1 (PubMed:20663085, PubMed:24812106).
Interacts with BRO1/ALIX (PubMed:22639582, PubMed:26342016).

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY Q9SZE4VPS2.2 Q0WTY43EBI-3865953, EBI-3865323
BINARY Q9SZE4VPS20.2 Q9FY893EBI-3865953, EBI-3865360
BINARY Q9SZE4VPS32.1 O821974EBI-3865953, EBI-3865938

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for coiled coil, region, compositional bias.

TypeIDPosition(s)Description
Coiled coil10-41
Coiled coil117-176
Region168-219Disordered
Compositional bias181-195Pro residues

Sequence similarities

Belongs to the SNF7 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence & Isoform

Align isoforms (2)
  • Sequence status
    Complete

This entry describes 2 isoforms produced by Alternative splicing.

Q9SZE4-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    219
  • Mass (Da)
    24,333
  • Last updated
    2000-05-01 v1
  • Checksum
    711E9EEB70450D6B
MMNRLFGKPKQEANALQTLDKLNETLEMLEKKEKVLLKKAGAEVEKAKEYSRAKNKRAAIQCLKRKRLYEGQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAMQKATNIDDVDKTMDEINEQTENMKQIQEALATPMGAAADFDEDELAAELDELESEELESQLLQPATTAPPLPSVPVPAGRQPARPVPQKRTAEEEELAALQAEMAL

Q9SZE4-2

  • Name
    2
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical

Sequence caution

The sequence AAM66053.1 differs from that shown. Reason: Erroneous initiation Truncated N-terminus.

Features

Showing features for alternative sequence, compositional bias.

TypeIDPosition(s)Description
Alternative sequenceVSP_0368041-27in isoform 2
Compositional bias181-195Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL078470
EMBL· GenBank· DDBJ
CAB43930.1
EMBL· GenBank· DDBJ
Genomic DNA
AL161574
EMBL· GenBank· DDBJ
CAB79674.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
AEE85593.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
AEE85594.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
AEE85595.1
EMBL· GenBank· DDBJ
Genomic DNA
AY042853
EMBL· GenBank· DDBJ
AAK68793.1
EMBL· GenBank· DDBJ
mRNA
AY072490
EMBL· GenBank· DDBJ
AAL66905.1
EMBL· GenBank· DDBJ
mRNA
AY088519
EMBL· GenBank· DDBJ
AAM66053.1
EMBL· GenBank· DDBJ
mRNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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