Q9SZ58 · BRAT1_ARATH
- ProteinBrassinosteroid-related acyltransferase 1
- GeneBAT1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids458 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
Brassinosteroids (BR) acyltransferase with acyl-CoA ligase activity toward brassinolide (BL), castasterone (CS), typhasterol (TY), 6-deoxotyphasterol (6-deoxoTY), and 6-deoxocastasterone (6-deoxoCS) and thus converts them to corresponding lauroyl esters (PubMed:23020607, PubMed:23071642, PubMed:23204503).
Regulates BR homeostasis and promotes BR-mediated cell growth regulation (PubMed:23071642, PubMed:23204503).
Involved in vascular bundle development (PubMed:23020607).
Regulates BR homeostasis and promotes BR-mediated cell growth regulation (PubMed:23071642, PubMed:23204503).
Involved in vascular bundle development (PubMed:23020607).
Pathway
Plant hormone biosynthesis; brassinosteroid biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 164 | Proton acceptor | ||||
Sequence: H |
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum | |
Cellular Component | nucleus | |
Molecular Function | acyltransferase activity, transferring groups other than amino-acyl groups | |
Molecular Function | long-chain fatty acid-CoA ligase activity | |
Biological Process | brassinosteroid biosynthetic process | |
Biological Process | phloem or xylem histogenesis | |
Biological Process | regulation of cell growth | |
Biological Process | response to abscisic acid | |
Biological Process | response to auxin | |
Biological Process | response to brassinosteroid |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameBrassinosteroid-related acyltransferase 1
- EC number
- Short namesBR-related acyltransferase 1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9SZ58
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Note: Localizes in the endoplasmic reticulum in young tissues and the phloem of vascular bundles.
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
No obvious growth phenotype under standard growth conditions (PubMed:23071642, PubMed:23204503).
The bat1-1 mutant exhibits longer stems before flowering, but reaches normal height after flowering, with larger inflorescence stems containing an increased number of vascular bundles (PubMed:23020607).
The bat1-1 mutant exhibits longer stems before flowering, but reaches normal height after flowering, with larger inflorescence stems containing an increased number of vascular bundles (PubMed:23020607).
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 31 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000436332 | 1-458 | Brassinosteroid-related acyltransferase 1 | |||
Sequence: MPMLMATRIDIIQKLNVYPRFQNHDKKKLITLSNLDRQCPLLMYSVFFYKNTTTRDFDSVFSNLKLGLEETMSVWYPAAGRLGLDGGGCKLNIRCNDGGAVMVEAVATGVKLSELGDLTQYNEFYENLVYKPSLDGDFSVMPLVVAQVTRFACGGYSIGIGTSHSLFDGISAYEFIHAWASNSHIHNKSNSKITNKKEDVVIKPVHDRRNLLVNRDAVRETNAAAICHLYQLIKQAMMTYQEQNRNLELPDSGFVIKTFELNGDAIESMKKKSLEGFMCSSFEFLAAHLWKARTRALGLRRDAMVCLQFAVDIRKRTETPLPEGFSGNAYVLASVASTARELLEELTLESIVNKIREAKKSIDQGYINSYMEALGGSNDGNLPPLKELTLISDWTKMPFHNVGFGNGGEPADYMAPLCPPVPQVAYFMKNPKDAKGVLVRIGLDPRDVNGFSNHFLDC |
Proteomic databases
PTM databases
Expression
Tissue specificity
Highly expressed in young tissues and vascular bundles (PubMed:23020607).
Mostly expressed in young leaves, primary roots, flowers (including petals and sepals), and siliques (PubMed:23204503).
Mostly expressed in young leaves, primary roots, flowers (including petals and sepals), and siliques (PubMed:23204503).
Induction
Induced by 24-epi-brassinolide (24-epiBL, eBL) and inhibited by abscisic acid (ABA) (PubMed:23204503).
Stimulated by auxin (PubMed:23020607).
Stimulated by auxin (PubMed:23020607).
Developmental stage
In young seedlings, mainly observed in the vascular cylinder of cotyledons, leaves and hypocotyls. Accumulates also in root tips, lateral root initiation sites and the maturation zone of the primary root. In adult plants, present in the vasculature of the inflorescence stems, especially in phloem cells.
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length458
- Mass (Da)51,145
- Last updated2000-05-01 v1
- Checksum62B75FCB1762DB30
Sequence caution
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL021636 EMBL· GenBank· DDBJ | CAA16598.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
AL049607 EMBL· GenBank· DDBJ | CAB40761.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AL161580 EMBL· GenBank· DDBJ | CAB79909.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002687 EMBL· GenBank· DDBJ | AEE85978.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY052280 EMBL· GenBank· DDBJ | AAK96473.1 EMBL· GenBank· DDBJ | mRNA | ||
AY139805 EMBL· GenBank· DDBJ | AAM98111.1 EMBL· GenBank· DDBJ | mRNA |