Q9SZ58 · BRAT1_ARATH

Function

function

Brassinosteroids (BR) acyltransferase with acyl-CoA ligase activity toward brassinolide (BL), castasterone (CS), typhasterol (TY), 6-deoxotyphasterol (6-deoxoTY), and 6-deoxocastasterone (6-deoxoCS) and thus converts them to corresponding lauroyl esters (PubMed:23020607, PubMed:23071642, PubMed:23204503).
Regulates BR homeostasis and promotes BR-mediated cell growth regulation (PubMed:23071642, PubMed:23204503).
Involved in vascular bundle development (PubMed:23020607).

Pathway

Plant hormone biosynthesis; brassinosteroid biosynthesis.

Features

Showing features for active site.

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TypeIDPosition(s)Description
Active site164Proton acceptor

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentnucleus
Molecular Functionacyltransferase activity, transferring groups other than amino-acyl groups
Molecular Functionlong-chain fatty acid-CoA ligase activity
Biological Processbrassinosteroid biosynthetic process
Biological Processphloem or xylem histogenesis
Biological Processregulation of cell growth
Biological Processresponse to abscisic acid
Biological Processresponse to auxin
Biological Processresponse to brassinosteroid

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Brassinosteroid-related acyltransferase 1
  • EC number
  • Short names
    BR-related acyltransferase 1
  • Alternative names
    • Protein DWARF AND ROUND LEAF 1
    • Protein PIZZA

Gene names

    • Name
      BAT1
    • Synonyms
      DRL1
      , PIZ
    • ORF names
      F10N7.280
      , F11C18.110
    • Ordered locus names
      At4g31910

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9SZ58
  • Secondary accessions
    • Q9SZ47

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Endoplasmic reticulum
Nucleus
Note: Localizes in the endoplasmic reticulum in young tissues and the phloem of vascular bundles.

Keywords

Phenotypes & Variants

Disruption phenotype

No obvious growth phenotype under standard growth conditions (PubMed:23071642, PubMed:23204503).
The bat1-1 mutant exhibits longer stems before flowering, but reaches normal height after flowering, with larger inflorescence stems containing an increased number of vascular bundles (PubMed:23020607).

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 31 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004363321-458

Proteomic databases

PTM databases

Expression

Tissue specificity

Highly expressed in young tissues and vascular bundles (PubMed:23020607).
Mostly expressed in young leaves, primary roots, flowers (including petals and sepals), and siliques (PubMed:23204503).

Induction

Induced by 24-epi-brassinolide (24-epiBL, eBL) and inhibited by abscisic acid (ABA) (PubMed:23204503).
Stimulated by auxin (PubMed:23020607).

Developmental stage

In young seedlings, mainly observed in the vascular cylinder of cotyledons, leaves and hypocotyls. Accumulates also in root tips, lateral root initiation sites and the maturation zone of the primary root. In adult plants, present in the vasculature of the inflorescence stems, especially in phloem cells.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the plant acyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    458
  • Mass (Da)
    51,145
  • Last updated
    2000-05-01 v1
  • Checksum
    62B75FCB1762DB30
MPMLMATRIDIIQKLNVYPRFQNHDKKKLITLSNLDRQCPLLMYSVFFYKNTTTRDFDSVFSNLKLGLEETMSVWYPAAGRLGLDGGGCKLNIRCNDGGAVMVEAVATGVKLSELGDLTQYNEFYENLVYKPSLDGDFSVMPLVVAQVTRFACGGYSIGIGTSHSLFDGISAYEFIHAWASNSHIHNKSNSKITNKKEDVVIKPVHDRRNLLVNRDAVRETNAAAICHLYQLIKQAMMTYQEQNRNLELPDSGFVIKTFELNGDAIESMKKKSLEGFMCSSFEFLAAHLWKARTRALGLRRDAMVCLQFAVDIRKRTETPLPEGFSGNAYVLASVASTARELLEELTLESIVNKIREAKKSIDQGYINSYMEALGGSNDGNLPPLKELTLISDWTKMPFHNVGFGNGGEPADYMAPLCPPVPQVAYFMKNPKDAKGVLVRIGLDPRDVNGFSNHFLDC

Sequence caution

The sequence CAA16598.1 differs from that shown. Reason: Erroneous gene model prediction

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL021636
EMBL· GenBank· DDBJ
CAA16598.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
AL049607
EMBL· GenBank· DDBJ
CAB40761.1
EMBL· GenBank· DDBJ
Genomic DNA
AL161580
EMBL· GenBank· DDBJ
CAB79909.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
AEE85978.1
EMBL· GenBank· DDBJ
Genomic DNA
AY052280
EMBL· GenBank· DDBJ
AAK96473.1
EMBL· GenBank· DDBJ
mRNA
AY139805
EMBL· GenBank· DDBJ
AAM98111.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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