Q9SWI1 · PKS1_ARATH

Function

function

May be responsible for light-regulated cytoplasmic sequestration of phytochromes or may be a negative regulator of phytochrome B signaling. Component of the network that modulates the very low-fluence response (VLFR) branch of phyA signaling. Acts positively in PHOT1 signaling. Regulates phytochrome-mediated photomorphogenesis and hypocotyl phototropism. Involved in the control of leaf flattening and leaf positioning. Promotes negative root phototropism and negatively regulates root gravitropism. May act by controlling auxin homeostasis.

Miscellaneous

PKS1, PKS2 and/or PKS4 are essential for phototropism but not for inhibition of gravitropism under long-term blue light irradiation.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentplasma membrane
Biological Processphototropism
Biological Processpositive gravitropism
Biological Processred or far-red light signaling pathway
Biological Processred, far-red light phototransduction
Biological Processresponse to far red light
Biological Processresponse to red light

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Protein PHYTOCHROME KINASE SUBSTRATE 1

Gene names

    • Name
      PKS1
    • ORF names
      T17M13.12
    • Ordered locus names
      At2g02950

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9SWI1
  • Secondary accessions
    • O80610

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

Phenotypes & Variants

Disruption phenotype

Increased hypocotyl growth inhibition and cotyledon unfolding responses in the very low fluence response (VLFR) mode. Reduced phototropic response. Reduced hyponasty when grown under blue light. Loss of negative root phototropism. Auxin accumulation in protoplasts.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 57 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00000584501-439Protein PHYTOCHROME KINASE SUBSTRATE 1
Modified residue238Phosphoserine
Modified residue244Phosphoserine

Post-translational modification

Phosphorylated on Ser and to a lower extent on Thr by phytochromes. Phosphorylation is stimulated twofold by red light.

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in young seedlings in both darkness and light. Moderate in leaves and very low in roots and flowers. Expressed in the elongation zone of the root and hypocotyl.

Induction

Up-regulated by white, red, far-red and blue light.

Developmental stage

Decreases with development.

Gene expression databases

Interaction

Subunit

Interacts with PKS2, RPT3, PHOT1, PHOT2 and the C-termini of both phytochromes A (phyA) and B (phyB). Binds both spectral forms of phytochrome, Pr and Pfr.

Binary interactions

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region1-22Disordered
Region54-80Disordered
Compositional bias64-80Basic and acidic residues
Region100-139Disordered
Region259-311Disordered
Compositional bias263-281Basic and acidic residues
Compositional bias296-310Polar residues
Region355-439Disordered
Compositional bias359-376Polar residues
Compositional bias390-406Polar residues
Compositional bias421-439Polar residues

Sequence similarities

Belongs to the PKS family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    439
  • Mass (Da)
    48,085
  • Last updated
    2002-05-10 v2
  • Checksum
    7A0A825FF7D3F3FC
MVTLTPSSASTPKTSFDFMKNNNSHSSLYVSSSSYLSSKEDALVTTKKLMEPSKTLNMSINPKQEEFGDEKKMVKKAPEDPEIGVFGAEKYFNGDMDSDQGSSVLSLTNPEVERTVVDSKQSAKKSTGTPSVRSESSWNSQSVLLQNKLVNSCNSSFKEKKNSNGQIQKVTNNKKSFLANLGCKCACSDGDSVDVEEKTSVKRSADPNISVITMRSSADMNTELIKIQKQEELSQRKSLEVFGSPVAIEKKSSVVQKKLPLPPWKSRTEEDDTKSEGSDSSSDLFEIEGLTGNPKPFLTRQGSDPASPTCYAPSEVSVEWSIVTASAADFSVMSECATSPVRRNRPTQIPRIPITAKSAPQRRKSSSSSGGNGFLMSCKSHKSVMVSGDLDRRSSMNKTQPSYVPRFPMETTKPKSFETRRRISNSSISHTQSSLLYSQ

Features

Showing features for compositional bias, sequence conflict.

TypeIDPosition(s)Description
Compositional bias64-80Basic and acidic residues
Sequence conflict196in Ref. 1; AAD38033
Compositional bias263-281Basic and acidic residues
Compositional bias296-310Polar residues
Compositional bias359-376Polar residues
Compositional bias390-406Polar residues
Compositional bias421-439Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF149053
EMBL· GenBank· DDBJ
AAD38033.1
EMBL· GenBank· DDBJ
mRNA
AC004138
EMBL· GenBank· DDBJ
AAC32913.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC05643.1
EMBL· GenBank· DDBJ
Genomic DNA
AF325064
EMBL· GenBank· DDBJ
AAK17132.1
EMBL· GenBank· DDBJ
mRNA
AY052708
EMBL· GenBank· DDBJ
AAK96612.1
EMBL· GenBank· DDBJ
mRNA
AY063721
EMBL· GenBank· DDBJ
AAL36071.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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