Q9SVY1 · ZWIP2_ARATH

Function

function

Transcriptional regulator required for normal differentiation of the ovary transmitting tract cells and pollen tube growth. In Arabidopsis, the transmitting tract facilitates the transport of pollen tubes to the ovules for fertilization (PubMed:17600712).
May play a role in the regulation of AGL8/FUL, which is required for normal pattern of cell division, expansion and differentiation during morphogenesis of the silique (PubMed:23515580).
Plays a role in replum development by the activation of the homeobox protein KNAT1 (PubMed:25039392).

Miscellaneous

The fruits of the gain-of-function mutant ntt-3D (T-DNA tagging) fail to dehisce.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA-binding transcription factor activity
Molecular Functionmetal ion binding
Biological Processcell fate determination
Biological Processfruit replum development
Biological Processpollen tube growth
Biological Processprimary root development
Biological Processregulation of DNA-templated transcription
Biological Processregulation of gene expression
Biological Processtransmitting tissue development

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Zinc finger protein WIP2
  • Alternative names
    • Protein NO TRANSMITTING TRACT
    • WIP-domain protein 2
      (AtWIP2
      )

Gene names

    • Name
      WIP2
    • Synonyms
      NTT
    • ORF names
      F15B8.140
    • Ordered locus names
      At3g57670

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9SVY1
  • Secondary accessions
    • Q84TI0

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

Reduced fertility, fruit length and seed set (PubMed:17600712).
Reduced replum width and cell number (PubMed:25039392).

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 22 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004313161-383Zinc finger protein WIP2

Proteomic databases

Expression

Tissue specificity

Expressed in developing carpels (PubMed:17600712).
Expressed in the shoot apical meristem and the replum (PubMed:25039392).

Gene expression databases

Interaction

Subunit

Can form homodimers. Interacts with BLH9, STM, AGL8/FUL, AGL1/SHP1 and AGL5/SHP2.

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY Q9SVY1AGL5 P293853EBI-1999175, EBI-621949

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, zinc finger, motif.

TypeIDPosition(s)Description
Region19-118Disordered
Compositional bias27-41Pro residues
Compositional bias50-68Pro residues
Compositional bias100-118Basic and acidic residues
Region147-191Disordered
Compositional bias152-179Basic and acidic residues
Zinc finger217-239C2H2-type 1
Zinc finger264-296C2H2-type 2; atypical
Motif293-296Nuclear localization signal
Zinc finger301-323C2H2-type 3; atypical
Zinc finger327-352C2H2-type 4; atypical
Motif336-339Nuclear localization signal
Region361-383Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    383
  • Mass (Da)
    43,337
  • Last updated
    2000-05-01 v1
  • Checksum
    9DDDCEE6E66A4506
MTDPYSNFFTDWFKSNPFHHYPNSSTNPSPHPLPPVTPPSSFFFFPQSGDLRRPPPPPTPPPSPPLREALPLLSLSPANKQQDHHHNHDHLIQEPPSTSMDVDYDHHHQDDHHNLDDDDHDVTVALHIGLPSPSAQEMASLLMMSSSSSSSRTTHHHEDMNHKKDLDHEYSHGAVGGGEDDDEDSVGGDGGCRISRLNKGQYWIPTPSQILIGPTQFSCPVCFKTFNRYNNMQMHMWGHGSQYRKGPESLRGTQPTGMLRLPCYCCAPGCRNNIDHPRAKPLKDFRTLQTHYKRKHGIKPFMCRKCGKAFAVRGDWRTHEKNCGKLWYCICGSDFKHKRSLKDHIKAFGNGHGAYGIDGFDEEDEPASEVEQLDNDHESMQSK

Features

Showing features for compositional bias, sequence conflict.

TypeIDPosition(s)Description
Compositional bias27-41Pro residues
Compositional bias50-68Pro residues
Compositional bias100-118Basic and acidic residues
Sequence conflict117in Ref. 4; AAO64176 and 6; BAF00501
Compositional bias152-179Basic and acidic residues
Sequence conflict184in Ref. 4; AAO64176 and 6; BAF00501

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF254447
EMBL· GenBank· DDBJ
AAL55722.1
EMBL· GenBank· DDBJ
mRNA
AL049660
EMBL· GenBank· DDBJ
CAB41188.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002686
EMBL· GenBank· DDBJ
AEE79685.1
EMBL· GenBank· DDBJ
Genomic DNA
BT005772
EMBL· GenBank· DDBJ
AAO64176.1
EMBL· GenBank· DDBJ
mRNA
BT021089
EMBL· GenBank· DDBJ
AAX12859.1
EMBL· GenBank· DDBJ
mRNA
AK228585
EMBL· GenBank· DDBJ
BAF00501.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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