Q9SSM4 · CHM1B_ARATH
- ProteinESCRT-related protein CHMP1B
- GeneCHMP1B
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids203 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Involved in ESCRT-dependent multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Mediates the MVB sorting of the auxin carriers PIN1, PIN2 and AUX1. Required for embryonic axis establishment and seedling growth (PubMed:19304934).
Required for autophagic degradation of plastid proteins. Promotes the efficient sequestration of cargo from plastids into autophagosomes. Mediates the efficient delivery of autophagic plastid bodies to the vacuole, but not into the cytoplasm (PubMed:25649438).
Required for autophagic degradation of plastid proteins. Promotes the efficient sequestration of cargo from plastids into autophagosomes. Mediates the efficient delivery of autophagic plastid bodies to the vacuole, but not into the cytoplasm (PubMed:25649438).
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | endosome membrane | |
Cellular Component | mitochondrion | |
Biological Process | embryo development ending in seed dormancy | |
Biological Process | embryonic axis specification | |
Biological Process | endosome transport via multivesicular body sorting pathway | |
Biological Process | protein transport | |
Biological Process | seedling development | |
Biological Process | vacuolar transport |
Keywords
- Biological process
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameESCRT-related protein CHMP1B
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9SSM4
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Endosome membrane ; Peripheral membrane protein
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
No visible phenotype under normal growth conditions, but double mutants chmp1a and chmp1b show embryo development defect.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 4 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000433027 | 1-203 | ESCRT-related protein CHMP1B | |||
Sequence: MGNTDKLMNQIFDLKFTSKSLQRQSRKCEKEEKAEKLKVKKAIEKGNMDGARIYAENAIRKRSEQMNYLRLASRLDAVVARLDTQAKMTTITKSMTNIVKSLESSLATGNLQKMSETMDSFEKQFVNMEVQAEFMENAMAGSTSLSTPEGEVNSLMQQVADDYGLEVSVGLPQPAGHAIPTKTEEKVDEDDLSRRLAELKARG |
Proteomic databases
PTM databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for coiled coil, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Coiled coil | 13-51 | |||||
Sequence: DLKFTSKSLQRQSRKCEKEEKAEKLKVKKAIEKGNMDGA | ||||||
Coiled coil | 109-140 | |||||
Sequence: GNLQKMSETMDSFEKQFVNMEVQAEFMENAMA | ||||||
Region | 172-203 | Disordered | ||||
Sequence: PQPAGHAIPTKTEEKVDEDDLSRRLAELKARG | ||||||
Compositional bias | 181-203 | Basic and acidic residues | ||||
Sequence: TKTEEKVDEDDLSRRLAELKARG |
Sequence similarities
Belongs to the SNF7 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length203
- Mass (Da)22,691
- Last updated2000-05-01 v1
- Checksum7E56E8D937B38CD2
Features
Showing features for sequence conflict, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 63 | in Ref. 4; AAM61431 | ||||
Sequence: S → R | ||||||
Compositional bias | 181-203 | Basic and acidic residues | ||||
Sequence: TKTEEKVDEDDLSRRLAELKARG |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC008017 EMBL· GenBank· DDBJ | AAD55650.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002684 EMBL· GenBank· DDBJ | AEE35406.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY059851 EMBL· GenBank· DDBJ | AAL24333.1 EMBL· GenBank· DDBJ | mRNA | ||
AY081673 EMBL· GenBank· DDBJ | AAM10235.1 EMBL· GenBank· DDBJ | mRNA | ||
AY084868 EMBL· GenBank· DDBJ | AAM61431.1 EMBL· GenBank· DDBJ | mRNA |