Q9SQ80 · G2OX1_PEA

Function

function

Catalyzes the 2-beta-hydroxylation of several biologically active gibberellins, leading to the homeostatic regulation of their endogenous level. Catabolism of gibberellins (GAs) plays a central role in plant development. Converts GA9/GA20 to GA51/GA29 and GA4/GA1 to GA34/GA8.

Catalytic activity

Cofactor

Fe cation (UniProtKB | Rhea| CHEBI:24875 )

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
0.024 μMGA20
Vmax pH TEMPERATURE[C] NOTES EVIDENCE
4.4 pmol/sec/mg

Pathway

Plant hormone biosynthesis; gibberellin biosynthesis.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site200Fe cation (UniProtKB | ChEBI)
Binding site202Fe cation (UniProtKB | ChEBI)
Binding site257Fe cation (UniProtKB | ChEBI)
Active site267

GO annotations

AspectTerm
Molecular FunctionC-19 gibberellin 2-beta-dioxygenase activity
Molecular Functionmetal ion binding
Biological Processgibberellin biosynthetic process
Biological Processgibberellin catabolic process
Biological Processresponse to light stimulus

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Gibberellin 2-beta-dioxygenase 1
  • EC number
  • Alternative names
    • GA 2-oxidase 1
    • Gibberellin 2-beta-hydroxylase 1
    • Gibberellin 2-oxidase 1
    • Protein SLENDER

Gene names

    • Name
      GA2OX1
    • Synonyms
      SLN

Organism names

  • Taxonomic identifier
  • Strains
    • cv. Alaska
    • cv. Torsdag
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Fabales > Fabaceae > Papilionoideae > 50 kb inversion clade > NPAAA clade > Hologalegina > IRL clade > Fabeae > Pisum

Accessions

  • Primary accession
    Q9SQ80
  • Secondary accessions
    • Q9SQ81
    • Q9SQJ0
    • Q9XHM4

Phenotypes & Variants

Disruption phenotype

Plants display to the slender phenotype, characterized by large amounts of GA20 that cannot be degraded, and is metabolized to excess GA1 on germination, producing plants with a characteristic slender or hyperelongated phenotype.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000673111-327Gibberellin 2-beta-dioxygenase 1

Expression

Tissue specificity

Predominantly expressed in roots, flowers, young fruits and seeds.

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain171-276Fe2OG dioxygenase

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    327
  • Mass (Da)
    36,811
  • Last updated
    2000-05-01 v1
  • Checksum
    2728A3B5C871CFB2
MVLLSKPTSEQYTYVRNNMPITFSSSIPLVDLSKPDAKTLIVKACEDFGFFKVINHGIPLDAISQLESEAFKFFSLPQTEKEKAGPANPFGYGNKRIGLNGDIGWIEYLLLTTNQDHNFSLYGEDIDKFRGLLKDYKCAMRNMACEILDLMAEGLKIQPKNVFSKLVMDKQSDCLFRVNHYPACPELAINGENLIGFGEHTDPQIISILRSNNTSGFQISLRDGSWISVPPDHSSFFINVGDSLQVMTNGRFKSVRHRVLANGIDPRLSMIYFCGPPLSEKIAPLPSLMKGKESLYKEFTWFEYKSSTYGSRLADNRLGNYERIAAT

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict116in Ref. 1; AAF13734 and 2; AAD45425
Sequence conflict127in Ref. 1; AAF08609

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF056935
EMBL· GenBank· DDBJ
AAF08609.1
EMBL· GenBank· DDBJ
mRNA
AF101382
EMBL· GenBank· DDBJ
AAF13734.1
EMBL· GenBank· DDBJ
mRNA Sequence problems.
AF101383
EMBL· GenBank· DDBJ
AAF13735.1
EMBL· GenBank· DDBJ
Genomic DNA
AF100955
EMBL· GenBank· DDBJ
AAD45425.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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