Q9SK02 · RA51B_ARATH
- ProteinDNA repair protein RAD51 homolog 2
- GeneRAD51B
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids370 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
May be involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 109-116 | ATP (UniProtKB | ChEBI) | |||
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | Rad51B-Rad51C-Rad51D-XRCC2 complex | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | ATP-dependent DNA damage sensor activity | |
Molecular Function | DNA binding | |
Molecular Function | DNA strand exchange activity | |
Biological Process | DNA repair | |
Biological Process | double-strand break repair via homologous recombination |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameDNA repair protein RAD51 homolog 2
- Short namesAtRAD51B
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9SK02
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000122944 | 1-370 | DNA repair protein RAD51 homolog 2 | ||
Proteomic databases
Expression
Tissue specificity
Preferentially expressed in flower buds and roots.
Induction
Induced by ionizing irradiation and treatment with a cross-linking reagent, cisplatin.
Gene expression databases
Structure
Sequence & Isoforms
- Sequence statusComplete
This entry describes 3 isoforms produced by Alternative splicing.
Q9SK02-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- SynonymsRAD51Balpha
- Length370
- Mass (Da)40,468
- Last updated2005-12-06 v2
- MD5 Checksum8D133153DF86132BB4AB38D65424558E
Q9SK02-2
- Name2
- SynonymsRAD51Bbeta
Q9SK02-3
- Name3
- SynonymsRAD51Bbeta
- NoteMay be due to an intron retention.
- Differences from canonical
- 359-370: HSDMINFHGDCS → IVDPDYVALFRTF
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
F4IIR6 | F4IIR6_ARATH | RAD51B | 338 |
Sequence caution
Features
Showing features for alternative sequence, sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Alternative sequence | VSP_016462 | 1-32 | in isoform 2 | ||
Alternative sequence | VSP_016463 | 270-275 | in isoform 2 | ||
Alternative sequence | VSP_016464 | 276-370 | in isoform 2 | ||
Sequence conflict | 330 | in Ref. 1; CAD70704 | |||
Sequence conflict | 353 | in Ref. 1; CAD70704 | |||
Alternative sequence | VSP_016465 | 359-370 | in isoform 3 | ||
Sequence conflict | 362-364 | In isoform Q9SK02-3; in Ref. 1; CAD70704 | |||
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AJ549435 EMBL· GenBank· DDBJ | CAD70704.1 EMBL· GenBank· DDBJ | mRNA | Frameshift | |
AB194809 EMBL· GenBank· DDBJ | BAD89163.1 EMBL· GenBank· DDBJ | mRNA | ||
AB194810 EMBL· GenBank· DDBJ | BAD89164.1 EMBL· GenBank· DDBJ | mRNA | ||
AC006587 EMBL· GenBank· DDBJ | AAD21490.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002685 EMBL· GenBank· DDBJ | AEC08140.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | AEC08141.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | AEC08143.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | ANM61239.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | ANM61240.1 EMBL· GenBank· DDBJ | Genomic DNA |