Q9SJE9 · ALMT1_ARATH

Function

function

Malate transporter critical for aluminum tolerance. The STOP1 transcription factor is required for ALMT1 expression.

Miscellaneous

Essential factor for aluminum (Al) tolerance but does not represent the major Al tolerance QTL also found on chromosome 1. Acts in parallel but independently of MATE, an aluminum-activated root citrate transporter.
A reversible phosphorylation acting both at the transcriptional and post-transcriptional levels is required to activate malate release in response to aluminum.

Activity regulation

Activated by external aluminum.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular Functionmalate transmembrane transporter activity
Biological Processmalate transmembrane transport
Biological Processmonoatomic ion transmembrane transport
Biological Processresponse to aluminum ion

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Aluminum-activated malate transporter 1
  • Short names
    AtALMT1

Gene names

    • Name
      ALMT1
    • ORF names
      T27G7.11
    • Ordered locus names
      At1g08430

Organism names

  • Taxonomic identifier
  • Strains
    • cv. Bay-0
    • cv. Cvi-0
    • cv. Landsberg erecta
    • cv. Nd-0
    • cv. No-0
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9SJE9
  • Secondary accessions
    • A8VPV4
    • Q15EV0
    • Q15EV1
    • Q15EV2
    • Q15EV3
    • Q15EV4

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane28-48Helical
Transmembrane51-71Helical
Transmembrane104-124Helical
Transmembrane133-153Helical
Transmembrane169-189Helical

Keywords

Phenotypes & Variants

Disruption phenotype

No visible phenotype when grown under normal conditions. Lack of aluminum-activated malate release and shorter roots when submitted to aluminum stress.

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variant33-36in strain: cv. Nd-0, cv. No-0
Natural variant36in strain: cv. Bay-0, cv. Landsberg erecta
Natural variant77-493in strain: cv. Wa-1; induces hypersensitivity to aluminum stress
Natural variant194in strain: cv. Bay-0
Natural variant257in strain: cv. Landsberg erecta
Natural variant298in strain: cv. Bay-0, cv. Cvi-0, cv. Landsberg erecta, cv. Nd-0, cv. No-0
Natural variant375in strain: cv. Cvi-0

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 44 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00004014601-493Aluminum-activated malate transporter 1
Modified residue320Phosphoserine
Modified residue327Phosphoserine
Modified residue385Phosphothreonine

Post-translational modification

Phosphorylated. A reversible phosphorylation is required for activation (By similarity).

Keywords

Proteomic databases

Expression

Tissue specificity

Expressed in roots, but not in shoots. Detected in the root apex in absence of aluminum stress and in root apices, the stele and endodermis of the elongating zone of primary and lateral roots after aluminum stress. Not expressed in cortical and epidermal cells.

Induction

Up-regulated by aluminum. Small induction by erbium (Er) and low pH stress, but no induction by cadmium, copper, lanthanum or sodium.

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region441-460Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    493
  • Mass (Da)
    55,077
  • Last updated
    2000-05-01 v1
  • Checksum
    CAEBF439C3E5CEC6
MEKVREIVREGIRVGNEDPRRIIHAFKVGLALVLVSSFYYYQPFGPFTDYFGINAMWAVMTVVVVFEFSVGATLGKGLNRGVATLVAGGLGIGAHQLARLSGATVEPILLVMLVFVQAALSTFVRFFPWVKTKFDYGILIFILTFALISLSGFRDEEIMDLAESRLSTVVIGGVSCILISIFVCPVWAGQDLHSLLASNFDTLSHFLQDFGDEYFEAREKGDYKVVEKRKKNLERYKSVLDSKSDEEALANYAEWEPPHGQFRFRHPWKQYVAVGALLRQCAYRIDALNSYINSDFQIPVDIKKKLETPLRRMSSESGNSMKEMSISLKQMIKSSSSDIHVSNSQAACKSLSTLLKSGILNDVEPLQMISLMTTVSMLIDIVNLTEKISESVHELASAARFKNKMRPTVLYEKSDSGSIGRAMPIDSHEDHHVVTVLHDVDNDRSNNVDDSRGGSSQDSCHHVAIKIVDDNSNHEKHEDGEIHVHTLSNGHLQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQ465038
EMBL· GenBank· DDBJ
ABF22742.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ465039
EMBL· GenBank· DDBJ
ABF22743.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ465040
EMBL· GenBank· DDBJ
ABF22744.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ465041
EMBL· GenBank· DDBJ
ABF22745.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ465042
EMBL· GenBank· DDBJ
ABF22746.1
EMBL· GenBank· DDBJ
Genomic DNA
AC006932
EMBL· GenBank· DDBJ
AAF22890.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002684
EMBL· GenBank· DDBJ
AEE28289.1
EMBL· GenBank· DDBJ
Genomic DNA
EU181365
EMBL· GenBank· DDBJ
ABW33503.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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