Q9SIS4 · IP5P9_ARATH

Function

function

Has phosphatase activity toward PtdIns(4,5)P2 and at a lower extent toward PtdIns(3,4,5)P3 but not toward Ins(1,4,5)P3. Functions in salt stress response by regulating reactive oxygen species (ROS) production, endocytosis, Ca2+ influx and stress-responsive genes expression.

Catalytic activity

GO annotations

AspectTerm
Molecular Functioninositol-polyphosphate 5-phosphatase activity
Molecular Functionphosphatidylinositol phosphate 5-phosphatase activity
Molecular Functionphosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
Molecular Functionphosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
Biological Processcellular response to salt stress
Biological Processphosphatidylinositol dephosphorylation
Biological Processregulation of clathrin-dependent endocytosis
Biological Processregulation of reactive oxygen species metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type IV inositol polyphosphate 5-phosphatase 9
  • EC number
  • Short names
    At5PTase9

Gene names

    • Name
      IP5P9
    • ORF names
      T23K3.9
    • Ordered locus names
      At2g01900

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9SIS4

Proteomes

Organism-specific databases

Genome annotation databases

Phenotypes & Variants

Disruption phenotype

Increased salt sensitivity with reduced production of reactive oxygen species (ROS), reduced Ca2+ influx, as well as decreased fluid-phase endocytosis.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 54 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004332591-417Type IV inositol polyphosphate 5-phosphatase 9

Proteomic databases

Expression

Tissue specificity

Specifically expressed in roots.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region258-273Catalytic 1
Region339-354Catalytic 2

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    417
  • Mass (Da)
    47,924
  • Last updated
    2000-05-01 v1
  • Checksum
    13A4527DEC6A6B7B
MWPRLVANKILRKSLGSNNFVADFPPNTDQKLIEASGLADERSKSILHNQHKTTLLNYKVFVSTWNVGGIVPDDGLDMEDLLETHKTPCDIYVLGFQEVVPLRASNVLGSDNNKVSTKWNSLIRDALNKRARPHRDEDLSESKGINGISQDFRCIISKQMVGILITVWVRGDLWPYIRYPSVSCVGCGIMGCLGNKGSVSVRFQLHETTFCFVCSHLASGGRDRDERQRNSDVNEILARSSFPRGSSLDLPKKILDHDRVIFLGDLNYRISLPEEKTRLLVESKKWNILLENDQLRMEIMNGQIFRGWQEGIVKFAPTYKYVPNSDLYYGCITYKKDEKKRAPAWCDRIIWYGNGLKQHEYTRGETKISDHRPVKAIFTTEITVTRRGKKIRNFFFSDRFEERIGDIDSKDYSWIST

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1P8AXI3A0A1P8AXI3_ARATHT5PTASE9425
A0A1P8AXD3A0A1P8AXD3_ARATHT5PTASE9408

Sequence caution

The sequence BX818920 differs from that shown. Reason: Miscellaneous discrepancy Sequencing errors.

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC007069
EMBL· GenBank· DDBJ
AAD21781.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC05514.1
EMBL· GenBank· DDBJ
Genomic DNA
BX818920
EMBL· GenBank· DDBJ
-mRNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp