Q9SIA5 · DTX1_ARATH

Function

function

Efflux carrier for plant-derived alkaloids, antibiotics, heavy metal and other toxic compounds. Involved in cadmium detoxification. Requires probably a proton-motive force for the efflux.

Caution

Mistakenly referred to as AT2G04070 in PubMed:11739388.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular Functionantiporter activity
Molecular Functionefflux transmembrane transporter activity
Molecular Functionxenobiotic transmembrane transporter activity
Biological Processcadmium ion transport
Biological Processsequestering of metal ion
Biological Processxenobiotic detoxification by transmembrane export across the plasma membrane

Keywords

Protein family/group databases

    • 2.A.66.1.8the multidrug/oligosaccharidyl-lipid/polysaccharide (mop) flippase superfamily

Names & Taxonomy

Protein names

  • Recommended name
    Protein DETOXIFICATION 1
  • Short names
    AtDTX1
  • Alternative names
    • Multidrug and toxic compound extrusion protein 1
      (MATE protein 1
      )

Gene names

    • Name
      DTX1
    • Synonyms
      TX1
    • ORF names
      F3L12.13
    • Ordered locus names
      At2g04040

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9SIA5

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane35-55Helical
Transmembrane66-86Helical
Transmembrane117-137Helical
Transmembrane146-166Helical
Transmembrane184-204Helical
Transmembrane208-228Helical
Transmembrane260-280Helical
Transmembrane289-309Helical
Transmembrane331-351Helical
Transmembrane370-390Helical
Transmembrane402-422Helical
Transmembrane433-453Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004053191-476Protein DETOXIFICATION 1

Proteomic databases

Expression

Tissue specificity

Ubiquitous. Highest expression in flowers and stems.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    476
  • Mass (Da)
    51,845
  • Last updated
    2000-05-01 v1
  • Checksum
    1A6952FD82B14424
MEEPFLLRDELLVPSQVTWHTNPLTVELKRVSRLAAPMATVTIAQYLLPVISVMVAGHNGELQLSGVALANSFTNVTGFSIMCGLVGALETLCGQAYGAKQYEKIGTYAYSAIASNIPICFLISILWLYIEKILISLGQDPEISRIAGSYAFWLIPALFGQAIVIPLSRFLLTQGLVIPLLFTAVTTLLFHVLVCWTLVFLFGLGCNGPAMATSVSFWFYAVILSCYVRFSSSCEKTRGFVSRDFVSSIKQFFQYGIPSAAMICLEWWLFEILILCSGLLPNPKLETSVLSICLTIETLHYVISAGVAAAVSTRVSNNLGAGNPQVARVSVLAGLCLWIVESAFFSILLFTCRNIIGYAFSNSKEVLDYVADLTPLLCLSFILDGFTAVLNGVARGSGWQHIGAWNNTVSYYLVGAPVGIYLAFSRELNGKGLWCGVVVGSTVQATILAIVTASINWKEQAEKARKRIVSTENRLA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC007178
EMBL· GenBank· DDBJ
AAD28687.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC05791.1
EMBL· GenBank· DDBJ
Genomic DNA
BT022022
EMBL· GenBank· DDBJ
AAY25434.1
EMBL· GenBank· DDBJ
mRNA
BT026371
EMBL· GenBank· DDBJ
ABH04478.1
EMBL· GenBank· DDBJ
mRNA
AK227153
EMBL· GenBank· DDBJ
BAE99196.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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