Q9SHL8 · PILS5_ARATH

Function

function

Involved in cellular auxin homeostasis by regulating auxin metabolism. Regulates intracellular auxin accumulation at the endoplasmic reticulum and thus auxin availability for nuclear auxin signaling.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionauxin efflux transmembrane transporter activity
Biological Processauxin-activated signaling pathway
Biological Processendoplasmic reticulum to cytosol auxin transport
Biological Processintracellular auxin homeostasis
Biological Processlateral root formation
Biological Processregulation of growth rate
Biological Processresponse to auxin

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Protein PIN-LIKES 5
  • Alternative names
    • Auxin efflux carrier-like protein 5

Gene names

    • Name
      PILS5
    • ORF names
      MJB20.6
    • Ordered locus names
      At2g17500

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9SHL8
  • Secondary accessions
    • B9DG37
    • Q8LGC5

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-5Lumenal
Transmembrane6-26Helical
Topological domain27-45Cytoplasmic
Transmembrane46-66Helical
Topological domain67-73Lumenal
Transmembrane74-94Helical
Topological domain95-106Cytoplasmic
Transmembrane107-127Helical
Topological domain128-144Lumenal
Transmembrane145-165Helical
Topological domain166-229Cytoplasmic
Transmembrane230-250Helical
Topological domain251-273Lumenal
Transmembrane274-294Helical
Topological domain295-312Cytoplasmic
Transmembrane313-333Helical
Topological domain334-337Lumenal
Transmembrane338-358Helical
Topological domain359-370Cytoplasmic
Transmembrane371-391Helical
Topological domain392-396Lumenal

Keywords

Phenotypes & Variants

Disruption phenotype

Increased root growth and lateral root initiation.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 19 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004365001-396Protein PIN-LIKES 5

Proteomic databases

Expression

Tissue specificity

Expressed in seedlings, cauline leaves and flowers.

Induction

Up-regulated by auxin application.

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    396
  • Mass (Da)
    43,394
  • Last updated
    2000-05-01 v1
  • Checksum
    81A78C8A017CF67D
MGFWSLLEVASMPVIQVLFMSLVGAFMASDRCKLFPVEARNSMNKVVFVLFAPALMFANLAQTVTLEDIISWWFMPVNMGLTFLIGGLLGWLVVKILKPPPYLEGLIVATCSAGNMGNLPIILVPAICDEDKSPFGNRSVCRTVGLSYASFSMALGGFYIWTYTFRLIKGSAMKVQAIEESEKIAIKSSNSDLEADHKTHLLGAPEDKENKVVKEKTGFWRKGVDFLHEILEELLAPPTLGAIIGFIFGAVRWLRNLIIGDDAPLRIVQSTAKLLGDGTIPCMTIILGGNLIQGLRSSAVKPMVVLGIVCVRYIAMPIIGIGIVLTAANLGFLPADPLFQYVLMLQFTLPPAMNIGTMTQLYNVAQDECSVLMLWTYLVAILALTVWSTIFLHLLV

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict216in Ref. 4; AAM60930
Sequence conflict311in Ref. 4; AAM60930

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC007584
EMBL· GenBank· DDBJ
AAD32907.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC06634.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC06635.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC06636.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC06637.1
EMBL· GenBank· DDBJ
Genomic DNA
AK226321
EMBL· GenBank· DDBJ
BAE98473.1
EMBL· GenBank· DDBJ
mRNA
AY084347
EMBL· GenBank· DDBJ
AAM60930.1
EMBL· GenBank· DDBJ
mRNA
AK317010
EMBL· GenBank· DDBJ
BAH19704.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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