Q9SH76 · PMA6_ARATH

Function

function

The plasma membrane H+ ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H+-symport. The resulting external acidification and/or internal alkinization may mediate growth responses (By similarity).

Catalytic activity

Features

Showing features for active site, binding site.

1949100200300400500600700800900
TypeIDPosition(s)Description
Active site3324-aspartylphosphate intermediate
Binding site590Mg2+ (UniProtKB | ChEBI)
Binding site594Mg2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionmetal ion binding
Molecular FunctionP-type proton-exporting transporter activity
Biological Processproton export across plasma membrane

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    ATPase 6, plasma membrane-type
  • EC number
  • Alternative names
    • Proton pump 6

Gene names

    • Name
      AHA6
    • ORF names
      F9A16.7
    • Ordered locus names
      At2g07560

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9SH76
  • Secondary accessions
    • Q84WR5

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-64Cytoplasmic
Transmembrane65-84Helical; Name=1
Topological domain85-96Extracellular
Transmembrane97-117Helical; Name=2
Topological domain118-246Cytoplasmic
Transmembrane247-267Helical; Name=3
Topological domain268-276Extracellular
Transmembrane277-294Helical; Name=4
Topological domain295-645Cytoplasmic
Transmembrane646-667Helical; Name=5
Topological domain668-672Extracellular
Transmembrane673-695Helical; Name=6
Topological domain696-711Cytoplasmic
Transmembrane712-732Helical; Name=7
Topological domain733-753Extracellular
Transmembrane754-774Helical; Name=8
Topological domain775-786Cytoplasmic
Transmembrane787-807Helical; Name=9
Topological domain808-815Extracellular
Transmembrane816-836Helical; Name=10
Topological domain837-949Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00000462791-949ATPase 6, plasma membrane-type
Modified residue883Phosphothreonine
Modified residue931Phosphoserine
Modified residue948Phosphothreonine

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in guard cells.

Gene expression databases

Interaction

Subunit

Binds to 14-3-3 proteins. The binding is induced by phosphorylation of Thr-948. Binding to 14-3-3 proteins activates the H+-ATPase (By similarity).

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region947-949Interaction with 14-3-3 proteins

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    949
  • Mass (Da)
    105,012
  • Last updated
    2000-05-01 v1
  • Checksum
    25C076607DB214EF
MAADISWDEIKKENVDLEKIPVDEVFQQLKCSREGLSSEEGRNRLQIFGANKLEEKVENKFLKFLGFMWNPLSWVMEAAAIMAIVLANGGGRPPDWQDFVGITCLLIINSTISFIEENNAGNAAAALMANLAPKTKVLRDGRWGEQEAAILVPGDLISIKLGDIVPADARLLEGDPLKIDQSALTGESLPATKHQGDEVFSGSTCKQGEIEAVVIATGVHTFFGKAAHLVDSTNNVGHFQKVLTAIGNFCICSIGIGMLIEIIIMYPIQHRKYRDGIDNLLVLLIGGIPIAMPTVLSVTMAIGSHRLSQQGAITKRMTAIEEMAGMDVLCSDKTGTLTLNKLTVDKNLIEVFSKDVDKDYVILLSARASRVENQDAIDTSIVNMLGDPKEARAGITEVHFLPFNPVEKRTAITYIDTNGEWHRCSKGAPEQIIELCDLKGETKRRAHEIIDKFAERGLRSLGVARQRVPEKDKESAGTPWEFVGLLPLFDPPRHDSAETIRRALDLGVNVKMITGDQLAIGKETGRRLGMGTNMYPSSSLLENKDDTTGGVPVDELIEKADGFAGVFPEHKYEIVRKLQERKHIVGMTGDGVNDAPALKKADIGIAVDDATDAARSASDIVLTEPGLSVIVSAVLTSRAIFQRMKNYTIYAVSITIRIVLGFMLVALIWEFDFSPFMVLIIAILNDGTIMTISKDRVKPSPIPDSWKLKEIFATGVVLGTYMALVTVVFFWLAHDTTFFSDKFGVRSLQGKDEELIAVLYLQVSIISQALIFVTRSRSWSFVERPGLLLLIAFFVAQLIATLIATYAHWEFARIKGCGWGWCGVIWIYSIVTYIPLDILKFITRYTLSGKAWNNMIENRTAFTTKKDYGRGEREAQWALAQRTLHGLKPPESMFEDTATYTELSEIAEQAKKRAEVARLREVHTLKGHVESVVKLKGLDIDNLNQHYTV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC007662
EMBL· GenBank· DDBJ
AAD32758.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC06056.1
EMBL· GenBank· DDBJ
Genomic DNA
BT002855
EMBL· GenBank· DDBJ
AAO22672.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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