Q9S9U6 · 1A111_ARATH
- Protein1-aminocyclopropane-1-carboxylate synthase 11
- GeneACS11
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids460 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
1-aminocyclopropane-1-carboxylate synthase (ACS) enzymes catalyze the conversion of S-adenosyl-L-methionine (SAM) into 1-aminocyclopropane-1-carboxylate (ACC), a direct precursor of ethylene.
Miscellaneous
The stability of ACS proteins, and the regulation of such stability, play a central role in ethylene biosynthesis.
Catalytic activity
- S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + H+ + S-methyl-5'-thioadenosine
Cofactor
Kinetics
KM | SUBSTRATE | pH | TEMPERATURE[C] | NOTES | EVIDENCE | |
---|---|---|---|---|---|---|
25 μM | AdoMet |
Vmax | pH | TEMPERATURE[C] | NOTES | EVIDENCE | |
---|---|---|---|---|---|
25.2 μM/h/mg |
pH Dependence
Optimum pH is 8.
Pathway
Alkene biosynthesis; ethylene biosynthesis via S-adenosyl-L-methionine; ethylene from S-adenosyl-L-methionine: step 1/2.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 45 | substrate | ||||
Sequence: E | ||||||
Binding site | 83 | substrate | ||||
Sequence: Y |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 1-aminocyclopropane-1-carboxylate synthase activity | |
Molecular Function | pyridoxal phosphate binding | |
Biological Process | ethylene biosynthetic process | |
Biological Process | fruit ripening |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name1-aminocyclopropane-1-carboxylate synthase 11
- EC number
- Short namesACC synthase 11
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9S9U6
Proteomes
Organism-specific databases
Genome annotation databases
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000123905 | 1-460 | 1-aminocyclopropane-1-carboxylate synthase 11 | |||
Sequence: MLSSKVVGDSHGQDSSYFLGWQEYEKNPFHESFNTSGIVQMGLAENQLSFDLIEKWLEEHPEVLGLKKNDESVFRQLALFQDYHGLPAFKDAMAKFMGKIRENKVKFDTNKMVLTAGSTSANETLMFCLANPGDAFLIPAPYYPGFDRDLKWRTGVEIVPIHCVSSNGYKITEDALEDAYERALKHNLNVKGVLITNPSNPLGTSTTREELDLLLTFTSTKKIHMVSDEIYSGTVFDSPEFTSVLEVAKDKNMGLDGKIHVVYSLSKDLGLPGFRVGLIYSNNEKVVSAATKMSSFGLISSQTQHLLANLLSDERFTTNYLEENKKRLRERKDRLVSGLKEAGISCLKSNAGLFCWVDLRHLLKSNTFEAEHSLWTKIVCEVGLNISPGSSCHCDEPGWFRVCFANMSDQTMEVAMDRVKGFVDNNNGGKQKRTMWDTRRRSLINKWVSKLSSVTCESER | ||||||
Modified residue | 267 | N6-(pyridoxal phosphate)lysine | ||||
Sequence: K |
Post-translational modification
May be processed at its C-terminus.
Proteomic databases
Expression
Tissue specificity
Expressed in roots.
Induction
By indole-3-acetic acid (IAA) and cycloheximide (CHX).
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length460
- Mass (Da)51,799
- Last updated2000-05-01 v1
- Checksum1A056347680E7E2F
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF160183 EMBL· GenBank· DDBJ | AAD48074.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AL161509 EMBL· GenBank· DDBJ | CAB81141.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002687 EMBL· GenBank· DDBJ | AEE82593.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF332405 EMBL· GenBank· DDBJ | AAG48768.1 EMBL· GenBank· DDBJ | mRNA |