Q9S7P5 · SPL12_ARATH
- ProteinSquamosa promoter-binding-like protein 12
- GeneSPL12
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids927 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3'.
Cofactor
Note: Binds 2 Zn2+ ions per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 127 | Zn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 132 | Zn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 149 | Zn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 152 | Zn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 168 | Zn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 171 | Zn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 175 | Zn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 187 | Zn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: C |
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA binding | |
Molecular Function | DNA-binding transcription factor activity | |
Molecular Function | metal ion binding | |
Biological Process | regulation of DNA-templated transcription |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameSquamosa promoter-binding-like protein 12
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9S7P5
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000132733 | 1-927 | Squamosa promoter-binding-like protein 12 | |||
Sequence: MEARIEGEVEGHSLEYGFSGKRSVEWDLNDWKWNGDLFVATQLNHGSSNSSSTCSDEGNVEIMERRRIEMEKKKKRRAVTVVAMEEDNLKDDDAHRLTLNLGGNNIEGNGVKKTKLGGGIPSRAICCQVDNCGADLSKVKDYHRRHKVCEIHSKATTALVGGIMQRFCQQCSRFHVLEEFDEGKRSCRRRLAGHNKRRRKANPDTIGNGTSMSDDQTSNYMLITLLKILSNIHSNQSDQTGDQDLLSHLLKSLVSQAGEHIGRNLVGLLQGGGGLQASQNIGNLSALLSLEQAPREDIKHHSVSETPWQEVYANSAQERVAPDRSEKQVKVNDFDLNDIYIDSDDTTDIERSSPPPTNPATSSLDYHQDSRQSSPPQTSRRNSDSASDQSPSSSSGDAQSRTDRIVFKLFGKEPNDFPVALRGQILNWLAHTPTDMESYIRPGCIVLTIYLRQDEASWEELCCDLSFSLRRLLDLSDDPLWTDGWLYLRVQNQLAFAFNGQVVLDTSLPLRSHDYSQIITVRPLAVTKKAQFTVKGINLRRPGTRLLCTVEGTHLVQEATQGGMEERDDLKENNEIDFVNFSCEMPIASGRGFMEIEDQGGLSSSFFPFIVSEDEDICSEIRRLESTLEFTGTDSAMQAMDFIHEIGWLLHRSELKSRLAASDHNPEDLFSLIRFKFLIEFSMDREWCCVMKKLLNILFEEGTVDPSPDAALSELCLLHRAVRKNSKPMVEMLLRFSPKKKNQTLAGLFRPDAAGPGGLTPLHIAAGKDGSEDVLDALTEDPGMTGIQAWKNSRDNTGFTPEDYARLRGHFSYIHLVQRKLSRKPIAKEHVVVNIPESFNIEHKQEKRSPMDSSSLEITQINQCKLCDHKRVFVTTHHKSVAYRPAMLSMVAIAAVCVCVALLFKSCPEVLYVFQPFRWELLEYGTS |
Proteomic databases
Expression
Structure
Family & Domains
Features
Showing features for region, zinc finger, motif, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 124-200 | Sufficient and necessary for DNA binding | ||||
Sequence: AICCQVDNCGADLSKVKDYHRRHKVCEIHSKATTALVGGIMQRFCQQCSRFHVLEEFDEGKRSCRRRLAGHNKRRRK | ||||||
Zinc finger | 124-201 | SBP-type | ||||
Sequence: AICCQVDNCGADLSKVKDYHRRHKVCEIHSKATTALVGGIMQRFCQQCSRFHVLEEFDEGKRSCRRRLAGHNKRRRKA | ||||||
Motif | 184-200 | Bipartite nuclear localization signal | ||||
Sequence: KRSCRRRLAGHNKRRRK | ||||||
Region | 191-213 | Disordered | ||||
Sequence: LAGHNKRRRKANPDTIGNGTSMS | ||||||
Region | 343-400 | Disordered | ||||
Sequence: SDDTTDIERSSPPPTNPATSSLDYHQDSRQSSPPQTSRRNSDSASDQSPSSSSGDAQS | ||||||
Compositional bias | 350-400 | Polar residues | ||||
Sequence: ERSSPPPTNPATSSLDYHQDSRQSSPPQTSRRNSDSASDQSPSSSSGDAQS |
Domain
The SBP-type zinc finger is required for the binding to DNA.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length927
- Mass (Da)104,142
- Last updated2000-05-01 v1
- Checksum69354E78FA56B940
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 350-400 | Polar residues | ||||
Sequence: ERSSPPPTNPATSSLDYHQDSRQSSPPQTSRRNSDSASDQSPSSSSGDAQS |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AJ132096 EMBL· GenBank· DDBJ | CAB56768.1 EMBL· GenBank· DDBJ | mRNA | ||
AJ132097 EMBL· GenBank· DDBJ | CAB56769.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AL138658 EMBL· GenBank· DDBJ | CAB75918.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002686 EMBL· GenBank· DDBJ | AEE80004.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT003817 EMBL· GenBank· DDBJ | AAO41870.1 EMBL· GenBank· DDBJ | mRNA |