Q9S7L8 · CDA5_ARATH
- ProteinCytidine deaminase 5
- GeneCDA5
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids346 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
Catalytic activity
- cytidine + H2O + H+ = uridine + NH4+
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 58-60 | substrate | |||
Binding site | 71 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 73 | Proton donor | |||
Binding site | 104 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 107 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | cytidine deaminase activity | |
Molecular Function | identical protein binding | |
Molecular Function | zinc ion binding | |
Biological Process | cytidine deamination |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCytidine deaminase 5
- EC number
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9S7L8
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000429147 | 1-346 | Cytidine deaminase 5 | ||
Proteomic databases
Expression
Gene expression databases
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 20-148 | CMP/dCMP-type deaminase 1 | |||
Domain | 183-304 | CMP/dCMP-type deaminase 2 | |||
Sequence similarities
Belongs to the cytidine and deoxycytidylate deaminase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length346
- Mass (Da)38,081
- Last updated2000-05-01 v1
- Checksum76417250E0AAD197
Sequence caution
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Sequence conflict | 95 | in Ref. 2; AAC69569 | |||
Sequence conflict | 109 | in Ref. 2; AAC69569 | |||
Sequence conflict | 345 | in Ref. 2; AAC69569 | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF121877 EMBL· GenBank· DDBJ | AAD30447.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF080676 EMBL· GenBank· DDBJ | AAC69569.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
AL079344 EMBL· GenBank· DDBJ | CAB45324.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AL161575 EMBL· GenBank· DDBJ | CAB79722.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002687 EMBL· GenBank· DDBJ | AEE85654.1 EMBL· GenBank· DDBJ | Genomic DNA |