Q9S7J9 · CAR9_ARATH
- ProteinProtein C2-DOMAIN ABA-RELATED 9
- GeneCAR9
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids185 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Stimulates the GTPase/ATPase activities of Obg-like ATPases (By similarity).
Mediates the transient calcium-dependent interaction of PYR/PYL/RCAR abscisic acid (ABA) receptors with the plasma membrane and thus regulates ABA sensitivity (PubMed:25465408, PubMed:31102784).
Mediates the transient calcium-dependent interaction of PYR/PYL/RCAR abscisic acid (ABA) receptors with the plasma membrane and thus regulates ABA sensitivity (PubMed:25465408, PubMed:31102784).
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 22 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 23 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 23 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 28 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 74 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 74 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 75 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 76 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 76 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 82 | Ca2+ 1 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Cellular Component | plasma membrane | |
Molecular Function | GTPase activator activity | |
Molecular Function | metal ion binding | |
Molecular Function | phospholipid binding | |
Biological Process | abscisic acid-activated signaling pathway | |
Biological Process | positive regulation of abscisic acid-activated signaling pathway | |
Biological Process | positive regulation of GTPase activity | |
Biological Process | response to abscisic acid |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameProtein C2-DOMAIN ABA-RELATED 9
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9S7J9
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Note: Localization at the plasma membrane increases upon abscisic acid (ABA) treatment, at the expense of nuclear localization.
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Reduced sensitivity to abscisic acid (ABA) in single and doule mutant lot1 car9 (PubMed:31102784).
When associated with disruption in CAR1, CAR4 and CAR5 genes, altered sensitivity to ABA during seedling establishment and root growth regulation (PubMed:25465408).
When associated with disruption in CAR1, CAR4 and CAR5 genes, altered sensitivity to ABA during seedling establishment and root growth regulation (PubMed:25465408).
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 19 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000433319 | 1-185 | Protein C2-DOMAIN ABA-RELATED 9 | ||
Proteomic databases
Expression
Interaction
Subunit
Binds to PYR/PYL/RCAR abscisic acid intracellular receptors in an ABA-independent manner, both at the plasma membrane and in the nucleus (By similarity).
Interacts with LOT1 in the nuleus; this interaction is repressed by abscisic acid (ABA) and is sensitive to calcium ion Ca2+, leading to free CAR9 accumulation at the plasma membrane (PubMed:31102784).
Interacts with LOT1 in the nuleus; this interaction is repressed by abscisic acid (ABA) and is sensitive to calcium ion Ca2+, leading to free CAR9 accumulation at the plasma membrane (PubMed:31102784).
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length185
- Mass (Da)21,054
- Last updated2000-05-01 v1
- Checksum7E2AC0D42F6D207F
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1P8AW00 | A0A1P8AW00_ARATH | CAR9 | 148 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC008148 EMBL· GenBank· DDBJ | AAD55494.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AC011663 EMBL· GenBank· DDBJ | AAG52327.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002684 EMBL· GenBank· DDBJ | AEE35116.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002684 EMBL· GenBank· DDBJ | AEE35117.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002684 EMBL· GenBank· DDBJ | ANM60806.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT026107 EMBL· GenBank· DDBJ | ABG48463.1 EMBL· GenBank· DDBJ | mRNA | ||
AY085364 EMBL· GenBank· DDBJ | AAM62594.1 EMBL· GenBank· DDBJ | mRNA |