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Q9RA47 · Q9RA47_THETH

  • Protein
    Methylenetetrahydrofolate reductase
  • Gene
    metF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Pathway

One-carbon metabolism; tetrahydrofolate interconversion.

Features

Showing features for binding site.

122920406080100120140160180200220
TypeIDPosition(s)Description
Binding site50FAD (UniProtKB | ChEBI)
Binding site107FAD (UniProtKB | ChEBI)
Binding site108FAD (UniProtKB | ChEBI)
Binding site109FAD (UniProtKB | ChEBI)
Binding site126FAD (UniProtKB | ChEBI)
Binding site127FAD (UniProtKB | ChEBI)
Binding site149FAD (UniProtKB | ChEBI)
Binding site156FAD (UniProtKB | ChEBI)
Binding site165FAD (UniProtKB | ChEBI)
Binding site169FAD (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionFAD binding
Molecular Functionmethylenetetrahydrofolate reductase (NADH) activity
Biological Processmethionine biosynthetic process
Biological Processtetrahydrofolate interconversion

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methylenetetrahydrofolate reductase

Gene names

    • Name
      metF

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • HB27
  • Taxonomic lineage
    Bacteria > Deinococcota > Deinococci > Thermales > Thermaceae > Thermus

Accessions

  • Primary accession
    Q9RA47

Subcellular Location

Phenotypes & Variants

Chemistry

Family & Domains

Sequence similarities

Belongs to the methylenetetrahydrofolate reductase family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    229
  • Mass (Da)
    25,476
  • Last updated
    2000-05-01 v1
  • MD5 Checksum
    2AF3359A5C90B6D6D10B42375BF978A1
MKIRDLLKARRGPLFSFEFFPPKDPEGEEALFRTLEELKAFRPAFVSITYGAMGSTRERSVAWAQRIQSLGLNPLAHLTVAGQSRKEVAEVLHRFVESGVENLLALRGDPPRGERVFRPHPEGFRYAAELVALIRERYGDRVSVGGAAYPEGHPESESLEADLRHFKAKVEAGLDFAITQLFFNNAHYFGFLERARRAGIGIPILPGIMPVTSYRQSAASPRSAGRASP

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue229

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB029373
EMBL· GenBank· DDBJ
BAA88680.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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