Q9R3K9 · Q9R3K9_ANAPH

Function

function

Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionATP binding
Molecular FunctionATP-dependent protein folding chaperone
Molecular Functionisomerase activity
Biological Processprotein refolding

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    60 kDa chaperonin

Gene names

    • Name
      groEL
    • Synonyms
      groESL

Organism names

  • Taxonomic identifier
  • Strains
    • HGE agent
    • AL-15
    • Tick-105
    • Tick-43
    • Dog-7414
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rickettsiales > Anaplasmataceae > Anaplasma > phagocytophilum group

Accessions

  • Primary accession
    Q9R3K9
  • Secondary accessions
    • Q9RB28
    • Q9RF17

Interaction

Subunit

Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.

Family & Domains

Sequence similarities

Belongs to the chaperonin (HSP60) family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    402
  • Mass (Da)
    43,035
  • Last updated
    2000-05-01 v1
  • Checksum
    61E1E8AC77E50190
MSNTVVTGEVLDKSIREVVRILEDAVGCTAGPKGLTVAISKPYGSPEITKDGYKVMKSIKPEEPLAAAIASIITQSASQCNDKVGDGTTTCSILTAKVIEEVSKAKAAGSDIVSIKNGILKAKEAVLTALMSMRREVEEDEIAQVATLSANGDKNIGSKIAQCVKEVGKDGVITVEESKGFKDLEVEKTDGMQFDRGYLSPYFVTNAEKMLVEFENPYIFLTEKKINLVQSILPILENVARSGRPLLIIAEDVEGEALSTLVLNKLRGGLQVAAVKAPGFGDRRKDMLGDIAVIVGAKYVVNDELAVKMEDIALSDLGTAKSVRITKDATTIIGSVDSSSESIASRTNQIKAQIENSSSDYDKEKLRERLAKLSGGVAVLKVGGSSEVEVKERKDRVEDALH

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue402

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF033101
EMBL· GenBank· DDBJ
AAC17990.1
EMBL· GenBank· DDBJ
Genomic DNA
AF173988
EMBL· GenBank· DDBJ
AAF01681.1
EMBL· GenBank· DDBJ
Genomic DNA
AF173989
EMBL· GenBank· DDBJ
AAF01682.1
EMBL· GenBank· DDBJ
Genomic DNA
AF202895
EMBL· GenBank· DDBJ
AAF25658.1
EMBL· GenBank· DDBJ
Genomic DNA
AF383227
EMBL· GenBank· DDBJ
AAL04058.1
EMBL· GenBank· DDBJ
Genomic DNA
AF478552
EMBL· GenBank· DDBJ
AAM28467.1
EMBL· GenBank· DDBJ
Genomic DNA
AF478553
EMBL· GenBank· DDBJ
AAM28468.1
EMBL· GenBank· DDBJ
Genomic DNA
AF478557
EMBL· GenBank· DDBJ
AAM28472.1
EMBL· GenBank· DDBJ
Genomic DNA
AF478558
EMBL· GenBank· DDBJ
AAM28473.1
EMBL· GenBank· DDBJ
Genomic DNA
AF478561
EMBL· GenBank· DDBJ
AAM28476.1
EMBL· GenBank· DDBJ
Genomic DNA
AF478562
EMBL· GenBank· DDBJ
AAM28477.1
EMBL· GenBank· DDBJ
Genomic DNA
AF478563
EMBL· GenBank· DDBJ
AAM28478.1
EMBL· GenBank· DDBJ
Genomic DNA
AY219849
EMBL· GenBank· DDBJ
AAO48717.1
EMBL· GenBank· DDBJ
Genomic DNA
AY279085
EMBL· GenBank· DDBJ
AAP33394.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281818
EMBL· GenBank· DDBJ
AAP34783.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281823
EMBL· GenBank· DDBJ
AAP34788.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281826
EMBL· GenBank· DDBJ
AAP34791.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281828
EMBL· GenBank· DDBJ
AAP34793.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281829
EMBL· GenBank· DDBJ
AAP34794.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281831
EMBL· GenBank· DDBJ
AAP34796.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281833
EMBL· GenBank· DDBJ
AAP34798.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281834
EMBL· GenBank· DDBJ
AAP34799.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281835
EMBL· GenBank· DDBJ
AAP34800.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281837
EMBL· GenBank· DDBJ
AAP34802.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281838
EMBL· GenBank· DDBJ
AAP34803.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281839
EMBL· GenBank· DDBJ
AAP34804.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281840
EMBL· GenBank· DDBJ
AAP34805.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281841
EMBL· GenBank· DDBJ
AAP34806.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281842
EMBL· GenBank· DDBJ
AAP34807.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281843
EMBL· GenBank· DDBJ
AAP34808.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281844
EMBL· GenBank· DDBJ
AAP34809.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281845
EMBL· GenBank· DDBJ
AAP34810.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281847
EMBL· GenBank· DDBJ
AAP34812.1
EMBL· GenBank· DDBJ
Genomic DNA
AY281849
EMBL· GenBank· DDBJ
AAP34814.1
EMBL· GenBank· DDBJ
Genomic DNA
AF548385
EMBL· GenBank· DDBJ
AAP86606.1
EMBL· GenBank· DDBJ
Genomic DNA
AF548386
EMBL· GenBank· DDBJ
AAP86607.1
EMBL· GenBank· DDBJ
Genomic DNA
EF392724
EMBL· GenBank· DDBJ
ABS50373.1
EMBL· GenBank· DDBJ
Genomic DNA
EU184703
EMBL· GenBank· DDBJ
ABX38718.1
EMBL· GenBank· DDBJ
Genomic DNA
EU246959
EMBL· GenBank· DDBJ
ABY76252.1
EMBL· GenBank· DDBJ
Genomic DNA
EU246961
EMBL· GenBank· DDBJ
ABY76254.1
EMBL· GenBank· DDBJ
Genomic DNA
EU381150
EMBL· GenBank· DDBJ
ACB13171.1
EMBL· GenBank· DDBJ
Genomic DNA
EU381151
EMBL· GenBank· DDBJ
ACB13172.1
EMBL· GenBank· DDBJ
Genomic DNA
EU381152
EMBL· GenBank· DDBJ
ACB13173.1
EMBL· GenBank· DDBJ
Genomic DNA
HM057224
EMBL· GenBank· DDBJ
ADI48316.1
EMBL· GenBank· DDBJ
Genomic DNA
HM057225
EMBL· GenBank· DDBJ
ADI48317.1
EMBL· GenBank· DDBJ
Genomic DNA
HM057226
EMBL· GenBank· DDBJ
ADI48318.1
EMBL· GenBank· DDBJ
Genomic DNA
HM057227
EMBL· GenBank· DDBJ
ADI48319.1
EMBL· GenBank· DDBJ
Genomic DNA
HM057228
EMBL· GenBank· DDBJ
ADI48320.1
EMBL· GenBank· DDBJ
Genomic DNA
HM057229
EMBL· GenBank· DDBJ
ADI48321.1
EMBL· GenBank· DDBJ
Genomic DNA
HM057230
EMBL· GenBank· DDBJ
ADI48322.1
EMBL· GenBank· DDBJ
Genomic DNA
HM057231
EMBL· GenBank· DDBJ
ADI48323.1
EMBL· GenBank· DDBJ
Genomic DNA
HM057232
EMBL· GenBank· DDBJ
ADI48324.1
EMBL· GenBank· DDBJ
Genomic DNA
HM057233
EMBL· GenBank· DDBJ
ADI48325.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ629906
EMBL· GenBank· DDBJ
ADV02370.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ629907
EMBL· GenBank· DDBJ
ADV02371.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ629908
EMBL· GenBank· DDBJ
ADV02372.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ629909
EMBL· GenBank· DDBJ
ADV02373.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ629910
EMBL· GenBank· DDBJ
ADV02374.1
EMBL· GenBank· DDBJ
Genomic DNA
KJ622307
EMBL· GenBank· DDBJ
AHY30849.1
EMBL· GenBank· DDBJ
Genomic DNA
KJ622308
EMBL· GenBank· DDBJ
AHY30850.1
EMBL· GenBank· DDBJ
Genomic DNA
KM215246
EMBL· GenBank· DDBJ
AJF93708.1
EMBL· GenBank· DDBJ
Genomic DNA
KM215251
EMBL· GenBank· DDBJ
AJF93713.1
EMBL· GenBank· DDBJ
Genomic DNA
KM215252
EMBL· GenBank· DDBJ
AJF93714.1
EMBL· GenBank· DDBJ
Genomic DNA
KM215261
EMBL· GenBank· DDBJ
AJF93722.1
EMBL· GenBank· DDBJ
Genomic DNA
KM215262
EMBL· GenBank· DDBJ
AJF93723.1
EMBL· GenBank· DDBJ
Genomic DNA
KM215263
EMBL· GenBank· DDBJ
AJF93724.1
EMBL· GenBank· DDBJ
Genomic DNA
KM215264
EMBL· GenBank· DDBJ
AJF93725.1
EMBL· GenBank· DDBJ
Genomic DNA
KM215265
EMBL· GenBank· DDBJ
AJF93726.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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