Q9R246 · Q9R246_MOUSE

  • Protein
    Mitochondrial uncoupling protein 2
  • Gene
    Ucp2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

Catalytic activity

  • (S)-malate(out) + H+(in) + phosphate(in) = (S)-malate(in) + H+(out) + phosphate(out)
  • (S)-malate(out) = (S)-malate(in)
  • H+(in) + L-aspartate(out) + phosphate(in) = H+(out) + L-aspartate(in) + phosphate(out)
  • H+(in) + malonate(out) + phosphate(in) = H+(out) + malonate(in) + phosphate(out)
  • H+(in) + oxaloacetate(out) + phosphate(in) = H+(out) + oxaloacetate(in) + phosphate(out)
  • H+(in) + phosphate(in) + sulfate(out) = H+(out) + phosphate(out) + sulfate(in)
  • H+(in) = H+(out)
  • L-aspartate(out) = L-aspartate(in)
  • a long-chain fatty acid(out) = a long-chain fatty acid(in)
  • chloride(in) = chloride(out)
  • phosphate(in) = phosphate(out)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular Functionoxidative phosphorylation uncoupler activity
Biological Processadaptive thermogenesis
Biological Processmitochondrial transmembrane transport
Biological Processresponse to cold

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Mitochondrial uncoupling protein 2
  • Alternative names
    • Solute carrier family 25 member 8

Gene names

    • Name
      Ucp2
    • Synonyms
      UCP2

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CAST/Ei
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q9R246

Organism-specific databases

Subcellular Location

Membrane
; Multi-pass membrane protein

Keywords

Family & Domains

Features

Showing features for repeat.

TypeIDPosition(s)Description
Repeat11-106Solcar
Repeat114-203Solcar
Repeat212-297Solcar

Sequence similarities

Belongs to the mitochondrial carrier (TC 2.A.29) family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    309
  • Mass (Da)
    33,314
  • Last updated
    2000-05-01 v1
  • Checksum
    B09794EEA99810F0
MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAGIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCAELVTYDLIKDTLLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYHSAGHCALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALMAACQSREAPF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF111999
EMBL· GenBank· DDBJ
AAD17199.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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