Q9R246 · Q9R246_MOUSE
- ProteinMitochondrial uncoupling protein 2
- GeneUcp2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids309 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
Catalytic activity
- (S)-malate(out) + H+(in) + phosphate(in) = (S)-malate(in) + H+(out) + phosphate(out)(S)-malate (out)CHEBI:15589
+ H+ (in)CHEBI:15378+ phosphate (in)CHEBI:43474= (S)-malate (in)CHEBI:15589+ H+ (out)CHEBI:15378+ phosphate (out)CHEBI:43474 - (S)-malate(out) = (S)-malate(in)
- H+(in) + L-aspartate(out) + phosphate(in) = H+(out) + L-aspartate(in) + phosphate(out)
- H+(in) + malonate(out) + phosphate(in) = H+(out) + malonate(in) + phosphate(out)
- H+(in) + oxaloacetate(out) + phosphate(in) = H+(out) + oxaloacetate(in) + phosphate(out)
- H+(in) + phosphate(in) + sulfate(out) = H+(out) + phosphate(out) + sulfate(in)
- H+(in) = H+(out)
- L-aspartate(out) = L-aspartate(in)
- a long-chain fatty acid(out) = a long-chain fatty acid(in)
- chloride(in) = chloride(out)
- phosphate(in) = phosphate(out)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Molecular Function | oxidative phosphorylation uncoupler activity | |
Biological Process | adaptive thermogenesis | |
Biological Process | mitochondrial transmembrane transport | |
Biological Process | response to cold |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameMitochondrial uncoupling protein 2
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ9R246
Organism-specific databases
Subcellular Location
Structure
Family & Domains
Features
Showing features for repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Repeat | 11-106 | Solcar | ||||
Sequence: PTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQF | ||||||
Repeat | 114-203 | Solcar | ||||
Sequence: AGIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCAELVTYDLIKDT | ||||||
Repeat | 212-297 | Solcar | ||||
Sequence: DDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYHSAGHCALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRA |
Sequence similarities
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length309
- Mass (Da)33,314
- Last updated2000-05-01 v1
- ChecksumB09794EEA99810F0