Q9QWI2 · Q9QWI2_MOUSE
- ProteinAmino acid transporter
- GeneSlc1a1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids375 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- D-aspartate(out) + H+(out) + K+(in) + 3 Na+(out) = D-aspartate(in) + H+(in) + K+(out) + 3 Na+(in)D-aspartate (out)CHEBI:29990
+ H+ (out)CHEBI:15378+ K+ (in)CHEBI:29103+ 3 Na+ (out)CHEBI:29101= D-aspartate (in)CHEBI:29990+ H+ (in)CHEBI:15378+ K+ (out)CHEBI:29103+ 3 Na+ (in)CHEBI:29101 - H+(out) + K+(in) + L-aspartate(out) + 3 Na+(out) = H+(in) + K+(out) + L-aspartate(in) + 3 Na+(in)
- H+(out) + K+(in) + L-glutamate(out) + 3 Na+(out) = H+(in) + K+(out) + L-glutamate(in) + 3 Na+(in)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | apical plasma membrane | |
Cellular Component | early endosome membrane | |
Cellular Component | late endosome membrane | |
Cellular Component | neuron projection | |
Cellular Component | recycling endosome membrane | |
Cellular Component | synapse | |
Molecular Function | acidic amino acid transmembrane transporter activity | |
Molecular Function | L-amino acid transmembrane transporter activity | |
Molecular Function | metal ion binding | |
Molecular Function | symporter activity | |
Biological Process | L-glutamate transmembrane transport |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameAmino acid transporter
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ9QWI2
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Apical cell membrane ; Multi-pass membrane protein
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 61-80 | Helical | ||||
Sequence: INVLGLIIFCLVFGLVIGKM | ||||||
Transmembrane | 101-122 | Helical | ||||
Sequence: IVQIIMCYMPIGILFLIAGKII | ||||||
Transmembrane | 134-160 | Helical | ||||
Sequence: GLYMATVLSGLAIHSLIVLPLLYFIVV | ||||||
Transmembrane | 167-188 | Helical | ||||
Sequence: FALGMAQALLTALMISSSSATL | ||||||
Transmembrane | 208-233 | Helical | ||||
Sequence: FVLPVGATINMDGTALYEAVAAVFIA | ||||||
Transmembrane | 245-262 | Helical | ||||
Sequence: IVTISITATAASIGAAGV |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Sequence similarities
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A1 subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length375
- Mass (Da)40,611
- Last updated2000-05-01 v1
- Checksum224BE1742163BA27