Q9P8P2 · PLB1_CRYNH

Function

function

Exhibits phospholipase B (PLB), lysophospholipase (LPL) and lysophospholipase/transacylase (LPTA) activities.

Caution

PubMed:10749672 describes peptide sequences that do not match PLB1, but originate from a copurified, contaminating chitin deacetylase.

Catalytic activity

Activity regulation

Inhibited by Fe3+ ion.

pH Dependence

Active only at acidic pHs.

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentextracellular region
Cellular Componentplasma membrane
Molecular Functionlysophospholipase activity
Molecular Functionphospholipase A2 activity
Biological Processglycerophospholipid catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phospholipase B
  • EC number
  • Alternative names
    • Lysophospholipase

Gene names

    • Name
      PLB1
    • ORF names
      CNAG_06085

Organism names

Accessions

  • Primary accession
    Q9P8P2
  • Secondary accessions
    • J9VV08

Proteomes

Subcellular Location

Secreted
Cell membrane
; Peripheral membrane protein
Note: Localizes to lipid rafts in the cell membrane prior to secretion.

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation.

TypeIDPosition(s)Description
Signal1-19
ChainPRO_000002463620-637Phospholipase B
Glycosylation50N-linked (GlcNAc...) asparagine
Glycosylation56N-linked (GlcNAc...) asparagine
Glycosylation122N-linked (GlcNAc...) asparagine
Glycosylation231N-linked (GlcNAc...) asparagine
Glycosylation246N-linked (GlcNAc...) asparagine
Glycosylation272N-linked (GlcNAc...) asparagine
Glycosylation314N-linked (GlcNAc...) asparagine
Glycosylation343N-linked (GlcNAc...) asparagine
Glycosylation387N-linked (GlcNAc...) asparagine
Glycosylation433N-linked (GlcNAc...) asparagine
Glycosylation481N-linked (GlcNAc...) asparagine
Glycosylation501N-linked (GlcNAc...) asparagine
Glycosylation528N-linked (GlcNAc...) asparagine
Glycosylation553N-linked (GlcNAc...) asparagine
Glycosylation572N-linked (GlcNAc...) asparagine
Glycosylation594N-linked (GlcNAc...) asparagine
Glycosylation606N-linked (GlcNAc...) asparagine

Post-translational modification

N-glycosylated.

Keywords

PTM databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain46-572PLA2c

Sequence similarities

Belongs to the lysophospholipase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    637
  • Mass (Da)
    68,818
  • Last updated
    2013-02-06 v2
  • Checksum
    7C052A69669B2276
MSIATATFAFSLFATIAFAVPPETPRIELQAERGLGDKSYAPWQVDCPSNVTWIRNATTGLGSGERAYIEAREKLVQPVIEQMMAARGLETPPRTPNIGVALSGGGYRAMLTGLGGIMGMMNESTEASESETGGWLDGVSYWAGLSGGSWATGTFMSNGGQLPTNLLENLWNIDSNLVFPDDDKLSFYTELYTETNAKSDLGFPIQITDVWGLAIGSHVLPERYQLSNTPNLTFSSLPSVVSALGNASLPMPIIIAADRKRREAGELVIAENATVWEFTPYEFGSWAFGSQYKSPGAFTPIEYLGTSVDDGSPNGTCWKGFDQLSFVMGTSATLFNGAFLELNGTDSGLLTNLITAFLADLGEDQADISRIPNTFSNYNSGENPIYNLTYITLVDAGETNQNIPLEPLLVPTRDVDAIVAFDSSYDTDYIWPNGTALRTTYERAKVLAEHENTRVLMPEVPSMNGFVNGGYNSRPTFFGCNDTTTPLIIYVPSYPWSFAANTSTYQLSYENDEANEMLLNGMRSLTLNHSVPTWPTCFACALTDRSFMYTSENRSTTCQKCFDTWCWAGDDNTTEPATYEPVINSVPPWLVANNLSIGVADAPASNESTAGTASSGAAKADVSMGMVALAAGLGLML

Sequence caution

The sequence AFR98312.2 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict6in Ref. 1; AAF65220
Sequence conflict619in Ref. 1; AAF65220

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF223383
EMBL· GenBank· DDBJ
AAF65220.1
EMBL· GenBank· DDBJ
Genomic DNA
CP003831
EMBL· GenBank· DDBJ
AFR98312.2
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.

Genome annotation databases

Similar Proteins

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