T2Rs function as bitter taste receptors.Chandrashekar J., Mueller K.L., Hoon M.A., Adler E., Feng L., Guo W., Zuker C.S., Ryba N.J.P.View abstractCited forCHARACTERIZATIONSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 100:703-711 (2000)Cited in22Mapped to19
The receptors and coding logic for bitter taste.Mueller K.L., Hoon M.A., Erlenbach I., Chandrashekar J., Zuker C.S., Ryba N.J.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 434:225-229 (2005)Cited in3Mapped to6
Receptors for bitter and sweet taste.Montmayeur J.-P., Matsunami H.View abstractCited forREVIEWSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCurr. Opin. Neurobiol. 12:366-371 (2002)Cited in41
Molecular mechanisms of bitter and sweet taste transduction.Margolskee R.F.Cited forREVIEWSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 277:1-4 (2002)Cited in41Mapped to7
Characterization and solubilization of bitter-responsive receptors that couple to gustducin.Ming D., Ruiz-Avila L., Margolskee R.F.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299623PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 95:8933-8938 (1998)Cited in1Mapped to24
Transduction of bitter and sweet taste by gustducin.Wong G.T., Gannon K.S., Margolskee R.F.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299623PubMedEurope PMCNature 381:796-800 (1996)Cited in1Mapped to28
Amplification and kinetics of the activation steps in phototransduction.Pugh E.N. Jr., Lamb T.D.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299623PubMedEurope PMCBiochim Biophys Acta 1141:111-149 (1993)Mapped to33
Photolyzed rhodopsin catalyzes the exchange of GTP for bound GDP in retinal rod outer segments.Kwok-Keung Fung B., Stryer L.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299623PubMedEurope PMCProc Natl Acad Sci U S A 77:2500-2504 (1980)Mapped to31
Flow of information in the light-triggered cyclic nucleotide cascade of vision.Fung B.K., Hurley J.B., Stryer L.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299623PubMedEurope PMCProc Natl Acad Sci U S A 78:152-156 (1981)Mapped to34
Effect of GTP on the rhodopsin-G-protein complex by transient formation of extra metarhodopsin II.Hofmann K.P.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299623PubMedEurope PMCBiochim Biophys Acta 810:278-281 (1985)Mapped to29
Anti-cancer stemness and anti-invasive activity of bitter taste receptors, TAS2R8 and TAS2R10, in human neuroblastoma cells.Seo Y., Kim Y.S., Lee K.E., Park T.H., Kim Y.View abstractAnnotationtargets cancer stem cells by suppressing cancer stemness characteristics and neuroblastoma cell invasionCategoriesExpressionSourceGeneRif: 50839PubMedEurope PMCPLoS One 12:e0176851-e0176851 (2017)Mapped to8
Major haplotypes of the human bitter taste receptor TAS2R41 encode functional receptors for chloramphenicol.Thalmann S., Behrens M., Meyerhof W.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299623PubMedEurope PMCBiochem Biophys Res Commun 435:267-273 (2013)Mapped to29
The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands.Born S., Levit A., Niv M.Y., Meyerhof W., Behrens M.View abstractAnnotationThe human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligandsCategoriesFunction, Disease & VariantsSourceGeneRif: 50839PubMedEurope PMCJ Neurosci 33:201-213 (2013)Mapped to4
The molecular receptive ranges of human TAS2R bitter taste receptors.Meyerhof W., Batram C., Kuhn C., Brockhoff A., Chudoba E., Bufe B., Appendino G., Behrens M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299623PubMedEurope PMCChem Senses 35:157-170 (2010)Mapped to29
Role of the G-protein subunit alpha-gustducin in taste cell responses to bitter stimuli.Caicedo A., Pereira E., Margolskee R.F., Roper S.D.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299623PubMedEurope PMCJ. Neurosci. 23:9947-9952 (2003)Cited in1Mapped to28
Dominant loss of responsiveness to sweet and bitter compounds caused by a single mutation in alpha-gustducin.Ruiz-Avila L., Wong G.T., Damak S., Margolskee R.F.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299623PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 98:8868-8873 (2001)Cited in2Mapped to28
Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium.Huang L., Shanker Y.G., Dubauskaite J., Zheng J.Z., Yan W., Rosenzweig S., Spielman A.I., Max M., Margolskee R.F.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299623PubMedEurope PMCNat. Neurosci. 2:1055-1062 (1999)Cited in3Mapped to43