The SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes.Zhang Y., Sun H., Pei R., Mao B., Zhao Z., Li H., Lin Y., Lu K.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-1011607PubMedEurope PMCCell Discov 7:31-31 (2021)Mapped to8
ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation.Miao G., Zhao H., Li Y., Ji M., Chen Y., Shi Y., Bi Y., Wang P., Zhang H.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-1011607PubMedEurope PMCDev. Cell 56:427-442 (2020)Cited in6Mapped to6
The Golgi puppet master: COG complex at center stage of membrane trafficking interactions.Willett R., Ungar D., Lupashin V.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6811025PubMedEurope PMCHistochem Cell Biol 140:271-283 (2013)Mapped to99+
COG complexes form spatial landmarks for distinct SNARE complexes.Willett R., Kudlyk T., Pokrovskaya I., Schonherr R., Ungar D., Duden R., Lupashin V.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6811025PubMedEurope PMCNat Commun 4:1553-1553 (2013)Mapped to17
The COG complex interacts with multiple Golgi SNAREs and enhances fusogenic assembly of SNARE complexes.Laufman O., Hong W., Lev S.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6811025PubMedEurope PMCJ Cell Sci 126:1506-1516 (2013)Mapped to17
The COG complex interacts directly with Syntaxin 6 and positively regulates endosome-to-TGN retrograde transport.Laufman O., Hong W., Lev S.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6811025PubMedEurope PMCJ Cell Biol 194:459-472 (2011)Mapped to39
Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing.Laufman O., Kedan A., Hong W., Lev S.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6811025PubMedEurope PMCEMBO J. 28:2006-2017 (2009)Cited in3Mapped to24
Interaction of the conserved oligomeric Golgi complex with t-SNARE Syntaxin5a/Sed5 enhances intra-Golgi SNARE complex stability.Shestakova A., Suvorova E., Pavliv O., Khaidakova G., Lupashin V.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6811025PubMedEurope PMCJ Cell Biol 179:1179-1192 (2007)Mapped to96
Cog3p depletion blocks vesicle-mediated Golgi retrograde trafficking in HeLa cells.Zolov S.N., Lupashin V.V.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6811025PubMedEurope PMCJ. Cell Biol. 168:747-759 (2005)Cited in2Mapped to94
The Sec34/Sec35p complex, a Ypt1p effector required for retrograde intra- Golgi trafficking, interacts with Golgi SNAREs and COPI vesicle coat proteins.Suvorova E.S., Duden R., Lupashin V.V.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-6811025PubMedEurope PMCJ. Cell Biol. 157:631-643 (2002)Cited in4Mapped to24