Q9NRP2 · COXM2_HUMAN

  • Protein
    COX assembly mitochondrial protein 2 homolog
  • Gene
    CMC2
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

May be involved in cytochrome c oxidase biogenesis.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrion

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    COX assembly mitochondrial protein 2 homolog

Gene names

    • Name
      CMC2
    • Synonyms
      C16orf61
    • ORF names
      DC13

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    Q9NRP2
  • Secondary accessions
    • D3DUK6

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Disease & Variants

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variantVAR_03381611in dbSNP:rs2303217

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 120 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Organism-specific databases

Miscellaneous

Genetic variation databases

PTM/Processing

Features

Showing features for chain, disulfide bond.

TypeIDPosition(s)Description
ChainPRO_00001929431-79COX assembly mitochondrial protein 2 homolog
Disulfide bond14↔47
Disulfide bond24↔37

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Organism-specific databases

Interaction

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY Q9NRP2C1orf216 Q8TAB53EBI-16780661, EBI-747505
BINARY Q9NRP2CTNNA3 Q9UI47-23EBI-16780661, EBI-11962928

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for domain, motif.

TypeIDPosition(s)Description
Domain11-55CHCH
Motif14-24Cx9C motif 1
Motif37-47Cx9C motif 2

Sequence similarities

Belongs to the CMC family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    79
  • Mass (Da)
    9,460
  • Last updated
    2000-10-01 v1
  • Checksum
    783381BD6DAFB7AA
MHPDLSPHLHTEECNVLINLLKECHKNHNILKFFGYCNDVDRELRKCLKNEYVENRTKSREHGIAMRKKLFNPPEESEK

Computationally mapped potential isoform sequences

There are 7 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
H3BTB6H3BTB6_HUMANCMC293
H3BRC3H3BRC3_HUMANCMC250
H3BQQ1H3BQQ1_HUMANCMC254
H3BPP2H3BPP2_HUMANCMC255
H3BP68H3BP68_HUMANCMC251
H3BNN8H3BNN8_HUMANCMC274
H3BN28H3BN28_HUMANCMC236

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF201935
EMBL· GenBank· DDBJ
AAF86871.1
EMBL· GenBank· DDBJ
mRNA
AC009079
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC092718
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CH471114
EMBL· GenBank· DDBJ
EAW95557.1
EMBL· GenBank· DDBJ
Genomic DNA
CH471114
EMBL· GenBank· DDBJ
EAW95559.1
EMBL· GenBank· DDBJ
Genomic DNA
CH471114
EMBL· GenBank· DDBJ
EAW95560.1
EMBL· GenBank· DDBJ
Genomic DNA
BC032631
EMBL· GenBank· DDBJ
AAH32631.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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