Q9NJI5 · Q9NJI5_LEITA

Function

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.

Features

Showing features for binding site.

121020406080100120140160180200
TypeIDPosition(s)Description
Binding site126GMP (UniProtKB | ChEBI)
Binding site127GMP (UniProtKB | ChEBI)
Binding site129GMP (UniProtKB | ChEBI)
Binding site130GMP (UniProtKB | ChEBI)
Binding site131GMP (UniProtKB | ChEBI)
Binding site133GMP (UniProtKB | ChEBI)
Binding site157GMP (UniProtKB | ChEBI)
Binding site178GMP (UniProtKB | ChEBI)
Binding site179GMP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionguanine phosphoribosyltransferase activity
Molecular Functionhypoxanthine phosphoribosyltransferase activity
Molecular Functionmetal ion binding
Molecular Functionnucleotide binding
Biological ProcessIMP salvage
Biological Processpurine ribonucleoside salvage

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Hypoxanthine phosphoribosyltransferase
  • EC number

Gene names

    • Name
      hgprt

Organism names

Accessions

  • Primary accession
    Q9NJI5

Organism-specific databases

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain48-182Phosphoribosyltransferase

Sequence similarities

Belongs to the purine/pyrimidine phosphoribosyltransferase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    210
  • Mass (Da)
    23,397
  • Last updated
    2000-10-01 v1
  • Checksum
    643042423F95054D
MSNSVKSPSDHVGDVGRRNYPMSARTLVTQEQVWAATAKCAKKIAADYKDFHLTADNPLYLLCVLKGSFIFTADLARFLADEGVPVKVEFICASSYGSGVETSGQVRMLLDVRDSVENRHIMLVEDIVDSAITLQYLMRFMLAKKPASLKTVVLLDKPSGRKVDVLVDYPVITIPHAFVIGYVWTFADLRGVPDICVLKKEYYEKAESKL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF139722
EMBL· GenBank· DDBJ
AAF61462.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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