Q9N0C7 · EPDR1_MACFA

Function

function

Binds anionic lipids and gangliosides at acidic pH.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular region
Cellular Componentlysosomal lumen
Molecular Functioncalcium ion binding
Molecular Functionlipid binding
Biological Processcell-matrix adhesion

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Mammalian ependymin-related protein 1
  • Short names
    MERP-1

Gene names

    • Name
      EPDR1
    • Synonyms
      MERP1
    • ORF names
      QccE-12983, QmoA-12340, QmoA-13475, QtrA-11871

Organism names

Accessions

  • Primary accession
    Q9N0C7
  • Secondary accessions
    • Q95K54
    • Q95K77

Proteomes

Subcellular Location

Lysosome lumen
Secreted
Note: Lysosomal and also secreted.

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond, glycosylation.

TypeIDPosition(s)Description
Signal1-37
ChainPRO_000000835238-224
Disulfide bond42↔172
Disulfide bond88↔222
Disulfide bond113↔210
Glycosylation130N-linked (GlcNAc...) asparagine
Glycosylation182N-linked (GlcNAc...) asparagine

Post-translational modification

N-glycosylated; the glycan contains mannose-6-phosphate moieties.

Keywords

PTM databases

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the ependymin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    224
  • Mass (Da)
    25,532
  • Last updated
    2008-03-18 v3
  • Checksum
    358E80B615AB4BB7
MPGRAPLHTVPGALGPWLLGCLWAWTLCGLCSLGAVGAPRPCQAPQQWEGRQVMYQQSSGRNSRALLSYDGLNQRVRVLDERKALIPCKRLFEYILLYKDGVMFQIEQATKQCSKMTLTEPWDPLDIPQNSTFEDQYSIGGPQEQIMVQEWSDRKSARSYETWIGIYTVKDCYPVQETFTKNYSVILSTRFFDIQLGIKDPSVFTPPSTCQIAQLEKMSEDCSW

Sequence caution

The sequence BAB01585.1 differs from that shown. Reason: Erroneous initiation
The sequence BAB60800.1 differs from that shown. Reason: Erroneous initiation
The sequence BAB62213.1 differs from that shown. Reason: Erroneous initiation
The sequence BAC41745.1 differs from that shown. Reason: Erroneous initiation

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict47in Ref. 1; BAB60800 and 2; BAC41745
Sequence conflict76in Ref. 1; BAB62213
Sequence conflict191in Ref. 1; BAB01585

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB046003
EMBL· GenBank· DDBJ
BAB01585.1
EMBL· GenBank· DDBJ
mRNA Different initiation
AB063094
EMBL· GenBank· DDBJ
BAB60800.1
EMBL· GenBank· DDBJ
mRNA Different initiation
AB066537
EMBL· GenBank· DDBJ
BAB62213.1
EMBL· GenBank· DDBJ
mRNA Different initiation
AB097520
EMBL· GenBank· DDBJ
BAC41745.1
EMBL· GenBank· DDBJ
mRNA Different initiation

Similar Proteins

Disclaimer

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