Q9MD82 · Q9MD82_MOUSE

  • Protein
    NADH-ubiquinone oxidoreductase chain 5
  • Gene
    mt-Nd5
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial respiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Biological Processmitochondrial electron transport, NADH to ubiquinone
Biological Processmitochondrial respiratory chain complex I assembly
Biological Processresponse to hydrogen peroxide
Biological Processresponse to hypoxia
Biological Processresponse to organonitrogen compound

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 5
  • EC number

Gene names

    • Name
      mt-Nd5
    • Synonyms
      mt-ND5
      , mt-Nd6
      , ND5
      , Nd5

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • C57BL/6J
    • SAMP1
    • SAMP8
    • SAMR1
    • C3H/He
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q9MD82

Organism-specific databases

Subcellular Location

Membrane
; Multi-pass membrane protein
Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-27Helical
Transmembrane39-56Helical
Transmembrane84-105Helical
Transmembrane117-134Helical
Transmembrane140-160Helical
Transmembrane172-191Helical
Transmembrane211-233Helical
Transmembrane245-266Helical
Transmembrane272-294Helical
Transmembrane301-319Helical
Transmembrane325-347Helical
Transmembrane368-386Helical
Transmembrane406-432Helical
Transmembrane453-472Helical
Transmembrane484-504Helical
Transmembrane586-604Helical

Keywords

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain68-117NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Domain134-417NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Domain422-601NADH dehydrogenase subunit 5 C-terminal

Sequence similarities

Belongs to the complex I subunit 5 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    607
  • Mass (Da)
    68,475
  • Last updated
    2000-10-01 v1
  • Checksum
    31C10862CDC78B10
MNIFTTSILLIFILLLSPILISMSNLIKHINFPLYTTTSIKFSFIISLLPLLMFFHNNMEYMITTWHWVTMNSMELKMSFKTDFFSILFTSVALFVTWSIMQFSSWYMHSDPNINRFIKYLTLFLITMLILTSANNMFQLFIGWEGVGIMSFLLIGWWYGRTDANTAALQAILYNRIGDIGFILAMVWFSLNMNSWELQQIMFSNNNDNLIPLMGLLIAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLVRFHPLTTNNNFILTTMLCLGALTTLFTAICALTQNDIKKIIAFSTSSQLGLMMVTLGMNQPHLAFLHICTHAFFKAMLFMCSGSIIHSLADEQDIRKMGNITKIMPFTSSCLVIGSLALTGMPFLTGFYSKDLIIEAINTCNTNAWALLITLIATSMTAMYSMRIIYFVTMTKPRFPPLISINENDPDLMNPIKRLAFGSIFAGFVISYNIPPTSIPVLTMPWFLKTTALIISVLGFLIALELNNLTMKLSMNKANPYSSFSTLLGFFPSIIHRITPMKSLNLSLKTSLTLLDLIWLEKTIPKSTSTLHTNMTTLTTNQKGLIKLYFMSFLINIILIIILYSINLE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY466499
EMBL· GenBank· DDBJ
AAR21205.1
EMBL· GenBank· DDBJ
Genomic DNA
AY533105
EMBL· GenBank· DDBJ
AAS01436.1
EMBL· GenBank· DDBJ
Genomic DNA
AY533106
EMBL· GenBank· DDBJ
AAS01449.1
EMBL· GenBank· DDBJ
Genomic DNA
AY533107
EMBL· GenBank· DDBJ
AAS01462.1
EMBL· GenBank· DDBJ
Genomic DNA
AY533108
EMBL· GenBank· DDBJ
AAS01475.1
EMBL· GenBank· DDBJ
Genomic DNA
AY999076
EMBL· GenBank· DDBJ
AAX83022.1
EMBL· GenBank· DDBJ
Genomic DNA
EF108330
EMBL· GenBank· DDBJ
ABK79103.1
EMBL· GenBank· DDBJ
Genomic DNA
EF108331
EMBL· GenBank· DDBJ
ABK79116.1
EMBL· GenBank· DDBJ
Genomic DNA
EF108332
EMBL· GenBank· DDBJ
ABK79129.1
EMBL· GenBank· DDBJ
Genomic DNA
EF108333
EMBL· GenBank· DDBJ
ABK79142.1
EMBL· GenBank· DDBJ
Genomic DNA
EF108334
EMBL· GenBank· DDBJ
ABK79155.1
EMBL· GenBank· DDBJ
Genomic DNA
EF108335
EMBL· GenBank· DDBJ
ABK79168.1
EMBL· GenBank· DDBJ
Genomic DNA
EF108336
EMBL· GenBank· DDBJ
ABK79181.1
EMBL· GenBank· DDBJ
Genomic DNA
EF108337
EMBL· GenBank· DDBJ
ABK79194.1
EMBL· GenBank· DDBJ
Genomic DNA
EF108338
EMBL· GenBank· DDBJ
ABK79207.1
EMBL· GenBank· DDBJ
Genomic DNA
EF108339
EMBL· GenBank· DDBJ
ABK79220.1
EMBL· GenBank· DDBJ
Genomic DNA
EF108340
EMBL· GenBank· DDBJ
ABK79233.1
EMBL· GenBank· DDBJ
Genomic DNA
EF108341
EMBL· GenBank· DDBJ
ABK79246.1
EMBL· GenBank· DDBJ
Genomic DNA
EU312160
EMBL· GenBank· DDBJ
ABX79712.1
EMBL· GenBank· DDBJ
Genomic DNA
EU312161
EMBL· GenBank· DDBJ
ABX79725.1
EMBL· GenBank· DDBJ
Genomic DNA
EU315228
EMBL· GenBank· DDBJ
ABX79738.1
EMBL· GenBank· DDBJ
Genomic DNA
EU315229
EMBL· GenBank· DDBJ
ABX79751.1
EMBL· GenBank· DDBJ
Genomic DNA
EU450583
EMBL· GenBank· DDBJ
ACA01533.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ803909
EMBL· GenBank· DDBJ
ACN91105.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ586004
EMBL· GenBank· DDBJ
ADR03166.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ877407
EMBL· GenBank· DDBJ
ADW83076.1
EMBL· GenBank· DDBJ
Genomic DNA
JF286601
EMBL· GenBank· DDBJ
ADZ23173.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ675026
EMBL· GenBank· DDBJ
AEN03379.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ675027
EMBL· GenBank· DDBJ
AEN03392.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ675028
EMBL· GenBank· DDBJ
AEN03405.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ675029
EMBL· GenBank· DDBJ
AEN03418.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ675030
EMBL· GenBank· DDBJ
AEN03431.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ675031
EMBL· GenBank· DDBJ
AEN03444.1
EMBL· GenBank· DDBJ
Genomic DNA
JQ003190
EMBL· GenBank· DDBJ
AEV56607.1
EMBL· GenBank· DDBJ
Genomic DNA
KP090294
EMBL· GenBank· DDBJ
AJE26566.1
EMBL· GenBank· DDBJ
Genomic DNA
KP260514
EMBL· GenBank· DDBJ
AJK91496.1
EMBL· GenBank· DDBJ
Genomic DNA
KP260515
EMBL· GenBank· DDBJ
AJK91509.1
EMBL· GenBank· DDBJ
Genomic DNA
KP260516
EMBL· GenBank· DDBJ
AJK91522.1
EMBL· GenBank· DDBJ
Genomic DNA
KP260517
EMBL· GenBank· DDBJ
AJK91535.1
EMBL· GenBank· DDBJ
Genomic DNA
KR020497
EMBL· GenBank· DDBJ
AKS10722.1
EMBL· GenBank· DDBJ
Genomic DNA
KY018919
EMBL· GenBank· DDBJ
ART65703.1
EMBL· GenBank· DDBJ
Genomic DNA
AB042524
EMBL· GenBank· DDBJ
BAA95650.1
EMBL· GenBank· DDBJ
Genomic DNA
AB042523
EMBL· GenBank· DDBJ
BAA95663.1
EMBL· GenBank· DDBJ
Genomic DNA
AB042809
EMBL· GenBank· DDBJ
BAA95805.1
EMBL· GenBank· DDBJ
Genomic DNA
AB049357
EMBL· GenBank· DDBJ
BAB13811.1
EMBL· GenBank· DDBJ
Genomic DNA
AK140457
EMBL· GenBank· DDBJ
BAE24397.1
EMBL· GenBank· DDBJ
mRNA
AP013030
EMBL· GenBank· DDBJ
BAM93593.1
EMBL· GenBank· DDBJ
Genomic DNA
AP014540
EMBL· GenBank· DDBJ
BAO42860.1
EMBL· GenBank· DDBJ
Genomic DNA
AP014541
EMBL· GenBank· DDBJ
BAO42873.1
EMBL· GenBank· DDBJ
Genomic DNA
AJ489607
EMBL· GenBank· DDBJ
CAD33917.1
EMBL· GenBank· DDBJ
Genomic DNA
AJ512208
EMBL· GenBank· DDBJ
CAD54442.1
EMBL· GenBank· DDBJ
Genomic DNA
MT937073
EMBL· GenBank· DDBJ
QPG85865.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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