Q9M9E8 · JMJ21_ARATH
- ProteinLysine-specific demethylase JMJ21
- GeneJMJ21
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids943 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
May function as histone H3 lysine demethylase and be involved in regulation of gene expression.
Cofactor
Note: Binds 1 Fe2+ ion per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 262 | Fe cation (UniProtKB | ChEBI); catalytic | |||
Binding site | 264 | Fe cation (UniProtKB | ChEBI); catalytic | |||
Binding site | 347 | Fe cation (UniProtKB | ChEBI); catalytic | |||
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | metal ion binding | |
Molecular Function | oxidoreductase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameLysine-specific demethylase JMJ21
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9M9E8
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000283365 | 1-943 | Lysine-specific demethylase JMJ21 | ||
Proteomic databases
PTM databases
Expression
Tissue specificity
Mostly expressed in leaves, and, to a lower extent, in inflorescences, roots, siliques and stems.
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 14-60 | F-box | |||
Domain | 216-379 | JmjC | |||
Compositional bias | 396-410 | Acidic residues | |||
Region | 396-438 | Disordered | |||
Sequence similarities
Belongs to the JARID1 histone demethylase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length943
- Mass (Da)108,505
- Last updated2011-02-08 v3
- MD5 ChecksumD690499B150D302D09E2B41D0334458A
Sequence caution
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 396-410 | Acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC013430 EMBL· GenBank· DDBJ | AAF71807.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002684 EMBL· GenBank· DDBJ | AEE36090.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BX817819 EMBL· GenBank· DDBJ | - | mRNA | No translation available. |