Q9M9E8 · JMJ21_ARATH

Function

function

May function as histone H3 lysine demethylase and be involved in regulation of gene expression.

Cofactor

Fe2+ (UniProtKB | Rhea| CHEBI:29033 )

Note: Binds 1 Fe2+ ion per subunit.

Features

Showing features for binding site.

1943100200300400500600700800900
TypeIDPosition(s)Description
Binding site262Fe cation (UniProtKB | ChEBI); catalytic
Binding site264Fe cation (UniProtKB | ChEBI); catalytic
Binding site347Fe cation (UniProtKB | ChEBI); catalytic

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular Functionmetal ion binding
Molecular Functionoxidoreductase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Lysine-specific demethylase JMJ21
  • EC number
  • Alternative names
    • F-box protein JMJ21
    • Jumonji domain-containing protein 21
      (AtJMJ21
      ; Protein JUMONJI 21
      )
    • Lysine-specific histone demethylase JMJ21
    • [histone H3]-trimethyl-L-lysine monodemethylase JMJ21

Gene names

    • Name
      JMJ21
    • ORF names
      F3F9.18
    • Ordered locus names
      At1g78280

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9M9E8

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002833651-943Lysine-specific demethylase JMJ21

Proteomic databases

PTM databases

Expression

Tissue specificity

Mostly expressed in leaves, and, to a lower extent, in inflorescences, roots, siliques and stems.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, compositional bias, region.

Type
IDPosition(s)Description
Domain14-60F-box
Domain216-379JmjC
Compositional bias396-410Acidic residues
Region396-438Disordered

Sequence similarities

Belongs to the JARID1 histone demethylase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    943
  • Mass (Da)
    108,505
  • Last updated
    2011-02-08 v3
  • MD5 Checksum
    D690499B150D302D09E2B41D0334458A
MTTLGQRDRRPDALGSLSVLPDETICVLLEYLAPRDIAHLACVSSVMYILCNEEPLWMSLCLRRAKGPLEYKGSWKKTTLHLEGVTQENDAYRKCFHFDGFMSLYLYKRFYRCNTSLDGFSFDNGNVERRRNISLDEFSKEYDAKKPVLLSGLADSWPASNTWTIDQLSEKYGEVPFRISQRSPNKISMKFKDYIAYMKTQRDEDPLYVFDDKFGEAAPELLKDYSVPHLFQEDWFEILDKESRPPYRWLIVGPERSGASWHVDPALTSAWNTLLCGRKRWALYPPGKVPLGVTVHVNEDDGDVSIDTPSSLQWWLDYYPLLADEDKPIECTLLPGETIYVPSGWWHCILNLEPTVAVTQNFVNKENFGFVCLDMAPGYHHKGVCRAGLLALDDENSEDLEEETHDEEDNTLSYSDLTRKEKRTRMNGGGETENREEDVNGVSKRYNMWKNGFSYDIDFLASFLDKERDHYNFPWSMGNSVGQREMRAWLSKLWVLKPEMRELIWKGACIALNAEKWLRCLEEVCTFHNLPLVTEDEKLPVGTGSNPVYLLSDYAIKLFVEGGLEQSMYGLGTELEFYDILGRADSPLKTHIPEVLASGILFFEKGSYKVVPWDGKRIPDIISSSSFDFDASMLNSEFPFGIWNKTLREHKNQGKPAPDSFGSLSSHVWPYIITKRCKGKIFAQLRDDLTWNDAQNLAFFLGQQLRNLHLLPYPPVTRPELLNVNAVHEELNIPAEWKVFVDALCQKKKDVTSRLENWGNPIPRALMTKIDEYIPDDFFVDLLHVFKETNGGDEIKPCTWIHSDVMDDNIHMEPYADDSVDGQHNSWRPSHILDFSDLTIGDPICDLIPIYLDVFRGDADLLKKLLENYGLPLIRSRSSENGTTKTADSTRKKVLSPSYRTMCYCILHEENVLGSIFSIWDELRTAESWEQVEQTVWSLLNTY

Sequence caution

The sequence AAF71807.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias396-410Acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC013430
EMBL· GenBank· DDBJ
AAF71807.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002684
EMBL· GenBank· DDBJ
AEE36090.1
EMBL· GenBank· DDBJ
Genomic DNA
BX817819
EMBL· GenBank· DDBJ
-mRNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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