Q9M811 · ROGFB_ARATH

Function

function

Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. Functions as a light-signaling switch that functions in root growth and development through the activation of Rop in a phytochrome-dependent manner. May act as a negative regulator of phytochrome-mediated primary root development.

Miscellaneous

Plants overexpressing ROPGEF11 show retarded root elongation and irregular root hair formation.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular Functionguanyl-nucleotide exchange factor activity
Biological Processroot development
Biological Processroot hair cell development

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Rop guanine nucleotide exchange factor 11
  • Short names
    AtRopGEF11
  • Alternative names
    • Phytochrome interacting RopGEF 1
    • Rho of plants guanine nucleotide exchange factor 11

Gene names

    • Name
      ROPGEF11
    • Synonyms
      PIRF1
    • ORF names
      F9I5.12
    • Ordered locus names
      At1g52240

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9M811
  • Secondary accessions
    • B3LF51
    • F4ICV0

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Cytoplasm
Note: Interacts with PHYA and PHYB in the cytoplasm in darkness.

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004238961-543Rop guanine nucleotide exchange factor 11

Proteomic databases

Expression

Tissue specificity

Highly expressed in elongating regions of roots and pollen grains. Expressed in flowers, and at lower levels in leaves and stems.

Gene expression databases

Interaction

Subunit

Interacts with ARAC4/ROP2, ARAC3/ROP, ARAC9/ROP8, PHYA and PHYB.

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntAct
BINARY Q9M811ROPGEF1 Q93ZY23EBI-16206717, EBI-4425188

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region61-89Disordered
Domain95-456PRONE

Domain

The PRONE (plant-specific Rop nucleotide exchanger) domain is responsible for the GEF activity.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete

This entry describes 1 isoforms produced by Alternative splicing. A number of isoforms are produced. According to EST sequences.

Q9M811-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    543
  • Mass (Da)
    61,655
  • Last updated
    2016-02-17 v2
  • Checksum
    0E0DF925F43F4B42
MVKAMEQEQETYKSRLFHFKNMNENSASRHVKSWSSDCAMRMDGSDNLDDDDNDMMMFRSQPGKCGSVDRPSLPIGGVTPNRNDKLPRVSSSDSMEALIILQAAMEQMKEKFSKLLLGEDMSGGGKGVSSALALSNAITNLAASAFGEQRRLEPMAVDRKTRWRREIGWLISVADYIVEFAPTQQTNKDGTSMEVMSTRQRTDLLCNIPALKKLDAMLLDCLDKFKDQDEFYYVKKDSPDSCETRNDEKWWLPAVKVPPNGLSEISRRFLQSQKECVNQVLKAAMAINAQVLSEMEIPESYLESLPKNGRASLGDVIYRMITVEMFDADQFLIEMDLSSEHKILDLKNRIEASIVIWKRKMVQKDTKSPWGSTVSIEKREQFEERAETILLLLKQGFPGISQSSLDISKIQFNRDVGLAILESYSRVLESLAHTVMSRIEDVLYADQLTQEPTNNAPSKNRYSLKENEKLREERLSFTEDMASGTLSDVMQWGNKNNEMKKESFFGDREKPLLSKVTGIMTNNKKSSYLDNLGAMRSPTARYS

Sequence caution

The sequence AAF29411.1 differs from that shown. Reason: Erroneous initiation Truncated N-terminus.

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC022354
EMBL· GenBank· DDBJ
AAF29411.1
EMBL· GenBank· DDBJ
Genomic DNA Different initiation
CP002684
EMBL· GenBank· DDBJ
AEE32773.2
EMBL· GenBank· DDBJ
Genomic DNA
BT033039
EMBL· GenBank· DDBJ
ACE79741.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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