Q9M391 · ATX3H_ARATH

Function

function

Interacts with key regulators of transcription and represses transcription. Acts as a histone-binding protein that regulates transcription. Acts as a deubiquitinating enzyme (By similarity).

Catalytic activity

  • Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
    EC:3.4.19.12 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

128020406080100120140160180200220240260280
TypeIDPosition(s)Description
Active site20Nucleophile
Active site126Proton acceptor
Active site141

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular Functioncysteine-type deubiquitinase activity
Biological Processprotein deubiquitination
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Ataxin-3 homolog
  • EC number
  • Alternative names
    • MJD1a-like
    • Machado-Joseph disease-like protein

Gene names

    • ORF names
      F24B22.90
    • Ordered locus names
      At3g54130

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9M391
  • Secondary accessions
    • Q53XG9

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000538361-280Ataxin-3 homolog

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Binary interactions

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain7-187Josephin
Region183-240Disordered
Compositional bias207-236Polar residues
Domain243-262UIM

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    280
  • Mass (Da)
    30,692
  • Last updated
    2000-10-01 v1
  • Checksum
    F4A1C9A3F9A25A78
MERTSNGGMLYHEVQESNLCAVHCVNTVLQGPFFSEFDLAAVAADLDGKERQVMLEGAAVGGFAPGDFLAEESHNVSLGGDFSIQVLQKALEVWDLQVIPLNCPDAEPAQIDPELESAFICHLHDHWFCIRKVNGEWYNFDSLLAAPQHLSKFYLSAFLDSLKGAGWSIFIVKGNFPQECPMSSSSEASNSFGQWLSPEDAERIRKNTSSGSSARNKRSNDNVNQQRRNQALSREEVQAFSEMEDDDLKAAIAASLLDASAAEANLGAVGTSEKETEKQK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias207-236Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL132957
EMBL· GenBank· DDBJ
CAB70987.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002686
EMBL· GenBank· DDBJ
AEE79191.1
EMBL· GenBank· DDBJ
Genomic DNA
BT010762
EMBL· GenBank· DDBJ
AAR23732.1
EMBL· GenBank· DDBJ
mRNA
BT010992
EMBL· GenBank· DDBJ
AAR24770.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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