Q9M330 · PSMF1_ARATH
- ProteinProbable proteasome inhibitor
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids302 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Could play an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome (By similarity).
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | endoplasmic reticulum | |
Cellular Component | nucleus | |
Cellular Component | plasma membrane | |
Cellular Component | proteasome complex | |
Molecular Function | endopeptidase inhibitor activity | |
Molecular Function | proteasome binding | |
Biological Process | cellular response to auxin stimulus | |
Biological Process | negative regulation of proteasomal protein catabolic process | |
Biological Process | proteasome-mediated ubiquitin-dependent protein catabolic process |
Community annotation
PTRE1 positively influences 26S proteasome activity and reduces 20S proteasome activity in Arabidopsis plants.
Source | Submission date | Contributor |
---|---|---|
PubMed:27109828 | 0000-0001-7501-8879 |
Names & Taxonomy
Protein names
- Recommended nameProbable proteasome inhibitor
Gene names
Community suggested name: PTRE1
Source | Submission date | Contributor |
---|---|---|
PubMed:27109828 | 0000-0001-7501-8879 |
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9M330
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Features
Showing features for initiator methionine, modified residue, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Initiator methionine | 1 | Removed | ||||
Sequence: M | ||||||
Modified residue | 2 | N-acetylalanine | ||||
Sequence: A | ||||||
Chain | PRO_0000220925 | 2-302 | Probable proteasome inhibitor | |||
Sequence: ANSQTVMAMIRLARPPFRNNHDKVAFAIHSSFVASGYILTATGRPAFADEALSSSSQNDVGIEGWNEFEGEYAFVYANPKKGSKKILVKCLAMDDKLLVDAIADGGAEPAHLEIKVGDYAEESNEGDYSAQFKNLDKLVTDLQSEIIDKLDGKPKPVASRAQSSSETNEEPRYYDDTPNPLGPQIHPSGVVVPPIPGNGGYSDLFPGPGAGMYPGRGGFGDGSMLVGPTDPRFFPFGDGSDRPGFMGPPHPGMPPPGARFDPYGPPGVPGFEPGRFTRQPPRGPGGGHPDLEHFPGGSDFI |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 151-188 | Disordered | ||||
Sequence: LDGKPKPVASRAQSSSETNEEPRYYDDTPNPLGPQIHP | ||||||
Region | 259-302 | Disordered | ||||
Sequence: ARFDPYGPPGVPGFEPGRFTRQPPRGPGGGHPDLEHFPGGSDFI |
Sequence similarities
Belongs to the proteasome inhibitor PI31 family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
This entry describes 1 isoforms produced by Alternative splicing. A number of isoforms are produced. According to EST sequences.
Q9M330-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length302
- Mass (Da)32,117
- Last updated2000-10-01 v1
- Checksum1DE8CFB5E55914E2
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
F4JBP8 | F4JBP8_ARATH | PTRE1 | 252 |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL132960 EMBL· GenBank· DDBJ | CAB88359.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002686 EMBL· GenBank· DDBJ | AEE79166.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY063998 EMBL· GenBank· DDBJ | AAL36354.1 EMBL· GenBank· DDBJ | mRNA | ||
AY117182 EMBL· GenBank· DDBJ | AAM51257.1 EMBL· GenBank· DDBJ | mRNA |