Q9M2T1 · AP3BA_ARATH
- ProteinAP3-complex subunit beta-A
- GeneAP3BA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids987 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
Part of the AP-3 complex, an adaptor-related complex which seems to be clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole. It also function in maintaining the identity of lytic vacuoles and in regulating the transition between storage and lytic vacuoles.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasmic vesicle membrane | |
Cellular Component | Golgi apparatus | |
Cellular Component | membrane coat | |
Biological Process | intracellular protein transport | |
Biological Process | vesicle-mediated transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameAP3-complex subunit beta-A
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9M2T1
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Cytoplasmic vesicle membrane ; Peripheral membrane protein
Note: Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
No obvious phenotype except defective lytic vacuoles with altered morphology and accumulation of proteins.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 93 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000397851 | 1-987 | AP3-complex subunit beta-A | |||
Sequence: MAGIRLHVIAPLALAAVSKCARDPAVYVRRCAANALPKLHDLRLEEHASAIEELVGILLNDHSPGVVGAAAAAFTSICPNNFKLIGKNYKKLCQILPDVEEWGQILLIGTLLRYVVARHGLVRESLMLSIHGTNSNGFCEKDGLGRDLTLDKEDGGKSDSFDVNLVSLVSKCYIQGPDEYLSRSSCTDTVSSAFDTKETTSIAHNEDVKILLQCTSPLLWSNNSAVVLAAAGVQWIMAPLEDVKKIVKPLLFLLRSSSASKYVVLCNILVFAKAVPSLFAPHFENFFICSSDAYQVKAYKLEMLSLIATTSSIASILREFEDYIKDPDRRFAADTVAAIGLCAKRLMTIPTTCLDGLLALVRQESFAGDFESADGEAGVLVQAVMSIQTMIERDPLRHEKVLIQLFRSLDSIKVAAARATIIWMVGVYCSLGHIIPRMLTTITKYLAWSFKSEASETKLQILNTIAKVLISAEAGDFHMLKRIVVYVFELGEYDLSYDIRDRTRFLKKLLSCKLASHEPAEDSVASQENIAAHVVEHVFGRKLKSVSPITLHNRFYLPGSLSQIVLHAAPGYEPLPKPCSFVYEEQDQLSDLDKQREAAADLDGSEESSETGDENGSSDYDSESSNGSDFSSEGDERTVSNDANDPAAPLIQISETSVSADQEELRSRRALDLWLDDQPSTSNQTPSALNSNQSSYAKISIGDVGSRVKPKSYSLVDPGNGSGLKVDYAFLSEVSNVSPLHVCVEVLFENSSAEPILEVNLEDEESMKVADSSEQTLVGKANASYNNIPTLIPMEEISCLEPHQSTKRLIQVRFHHHLLPMRLTLHYNEKKVPVKLRPDLGYLVKPFSMSIEEFLATESRLPGMFEYSRRCTFDDHVKDSRTENGKDKFLSICESITLKVLSNSNLHLVSVDLPVANSLEDATGLRLRFSSKILSSEIPLLITITVEGKCTEVLNLTVKINCEETVFGLNLLNRIANFMVEPSSSAT |
Proteomic databases
PTM databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 586-662 | Disordered | ||||
Sequence: QDQLSDLDKQREAAADLDGSEESSETGDENGSSDYDSESSNGSDFSSEGDERTVSNDANDPAAPLIQISETSVSADQ | ||||||
Compositional bias | 587-603 | Basic and acidic residues | ||||
Sequence: DQLSDLDKQREAAADLD | ||||||
Compositional bias | 618-634 | Polar residues | ||||
Sequence: SDYDSESSNGSDFSSEG | ||||||
Compositional bias | 645-660 | Polar residues | ||||
Sequence: DPAAPLIQISETSVSA |
Sequence similarities
Belongs to the adaptor complexes large subunit family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
This entry describes 1 isoforms produced by Alternative splicing. A number of isoforms are produced. According to EST sequences.
Q9M2T1-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length987
- Mass (Da)108,650
- Last updated2010-10-05 v2
- ChecksumAFFB1BC0099AD86D
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
F4IWW1 | F4IWW1_ARATH | PAT2 | 1115 |
Sequence caution
Features
Showing features for sequence conflict, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 398 | in Ref. 3; AAL24128 | ||||
Sequence: H → R | ||||||
Compositional bias | 587-603 | Basic and acidic residues | ||||
Sequence: DQLSDLDKQREAAADLD | ||||||
Compositional bias | 618-634 | Polar residues | ||||
Sequence: SDYDSESSNGSDFSSEG | ||||||
Compositional bias | 645-660 | Polar residues | ||||
Sequence: DPAAPLIQISETSVSA | ||||||
Sequence conflict | 764 | in Ref. 3; AAL24128 | ||||
Sequence: E → G |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL132975 EMBL· GenBank· DDBJ | CAB75906.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002686 EMBL· GenBank· DDBJ | AEE79390.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY059780 EMBL· GenBank· DDBJ | AAL24128.1 EMBL· GenBank· DDBJ | mRNA |