Q9M1G5 · NDC80_ARATH

Function

function

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity to ensure proper cell division.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentNdc80 complex
Molecular Functionmicrotubule binding
Biological Processattachment of mitotic spindle microtubules to kinetochore
Biological Processcell division

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Kinetochore protein NDC80 homolog

Gene names

    • Name
      NDC80
    • ORF names
      T14E10_200
    • Ordered locus names
      At3g54630

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9M1G5
  • Secondary accessions
    • A4FVQ9

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004441021-568Kinetochore protein NDC80 homolog

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Subunit

Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, coiled coil.

TypeIDPosition(s)Description
Region1-59Disordered
Compositional bias28-48Polar residues
Coiled coil241-334
Coiled coil433-469

Sequence similarities

Belongs to the NDC80/HEC1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    568
  • Mass (Da)
    63,332
  • Last updated
    2000-10-01 v1
  • Checksum
    92B151FD6D486995
MRGGAAGKRRTTVGFGGAPPPPPPSIEQQRHLFNSRDSDASFASSRPSSIGLGGRGASDDRSSMIRFINAFLSTHNFPISIRGNPVPSVKDISETLKFLLSALDYPCDSIKWDEDLVFFLKSQKCPFKITKSSLKAPNTPHNWPTVLAVVHWLAELARFHQHLVSNSTSVPEDNSMNFFAIQSFGHFIRGEDDKVNDLDSQFLGKLEAEKTSVAETISGCEKISGELEAKLESLRKGPSKKESLEKVKADLENDVNKFRTIVVEYTDRNPAMEKVVEEKAKELKAKEEERERISVENKELKKSVELQNFSAADVNRMRRELQAVERDVADAEVARDGWDQKAWELNSQIRNQFHQIQTLAIDCNQALRRLKLDIQFAVNERGETPAAVMGVDYKSVVKPALCSLCDGIKGSSAEKVEELVTLQHHKSEMASKIESKRSLLGSIQLQINDLEEKMKLVKKETQELSTKCDLEAKTLVESVKAEALNLEVVEKEAAEFVKASELRLQEAVKESEEEVQACAAQLFALIDSISKQKEYMDSKISEIKTGVADTASAVSEIYKANFKKNLGI

Features

Showing features for compositional bias, sequence conflict.

TypeIDPosition(s)Description
Compositional bias28-48Polar residues
Sequence conflict260in Ref. 3; ABO38770

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL138656
EMBL· GenBank· DDBJ
CAB77583.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002686
EMBL· GenBank· DDBJ
AEE79259.1
EMBL· GenBank· DDBJ
Genomic DNA
BT030357
EMBL· GenBank· DDBJ
ABO38770.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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