Q9M0G4 · TYDC2_ARATH
- ProteinTyrosine decarboxylase 2
- GeneTYRDC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids545 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Converts tyrosine into tyramine, a precursor of isoquinoline alkaloids and various amides.
Catalytic activity
- H+ + L-tyrosine = CO2 + tyramineThis reaction proceeds in the forward direction.
Cofactor
Kinetics
KM | SUBSTRATE | pH | TEMPERATURE[C] | NOTES | EVIDENCE | |
---|---|---|---|---|---|---|
745 μM | L-tyrosine |
Vmax | pH | TEMPERATURE[C] | NOTES | EVIDENCE | |
---|---|---|---|---|---|
61.35 nmol/sec/mg | with L-tyrosine as substrate |
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | carboxy-lyase activity | |
Molecular Function | pyridoxal phosphate binding | |
Molecular Function | tyrosine decarboxylase activity | |
Biological Process | amino acid metabolic process | |
Biological Process | carboxylic acid metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTyrosine decarboxylase 2
- EC number
- Short namesAtTYDC
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9M0G4
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
Phenotypes & Variants
Disruption phenotype
Slight reduction of pollen grain size.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 45 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000146994 | 1-545 | Tyrosine decarboxylase 2 | |||
Sequence: MFKPQHMYDREFGTGNGYSNGNGYTNGNGHTNGNGNYNGNGHVNGNGKANGAKVVKMKPMDSELLREQGHIMVDFIADYYKNLQDSPQDFPVLSQVQPGYLRDMLPDSAPERPESLKELLDDVSKKIMPGITHWQSPSYFAYYASSTSVAGFLGEMLNAGLSVVGFTWLTSPAATELEIIVLDWLAKLLQLPDHFLSTGNGGGVIQGTGCEAVLVVVLAARDRILKKVGKTLLPQLVVYGSDQTHSSFRKACLIGGIHEENIRLLKTDSSTNYGMPPESLEEAISHDLAKGFIPFFICATVGTTSSAAVDPLVPLGNIAKKYGIWLHVDAAYAGNACICPEYRKFIDGIENADSFNMNAHKWLFANQTCSPLWVKDRYSLIDALKTNPEYLEFKVSKKDTVVNYKDWQISLSRRFRSLKLWMVLRLYGSENLRNFIRDHVNLAKHFEDYVAQDPSFEVVTTRYFSLVCFRLAPVDGDEDQCNERNRELLAAVNSTGKIFISHTALSGKFVLRFAVGAPLTEEKHVTEAWQIIQKHASKFTRNDHY | ||||||
Modified residue | 361 | N6-(pyridoxal phosphate)lysine | ||||
Sequence: K |
Proteomic databases
Expression
Tissue specificity
Expressed specifically in flowers.
Induction
Induced by drougt stress, wounding and methyl jasmonate.
Gene expression databases
Interaction
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 23-45 | Disordered | ||||
Sequence: GYTNGNGHTNGNGNYNGNGHVNG |
Sequence similarities
Belongs to the group II decarboxylase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
This entry describes 1 isoforms produced by Alternative splicing. A number of isoforms are produced. According to EST sequences.
Q9M0G4-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length545
- Mass (Da)60,804
- Last updated2000-10-01 v1
- Checksum96D297C718BE9031
Computationally mapped potential isoform sequences
There are 6 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1P8B7T4 | A0A1P8B7T4_ARATH | TYRDC | 566 | ||
A0A1P8B7T5 | A0A1P8B7T5_ARATH | TYRDC | 428 | ||
A0A1P8B7T7 | A0A1P8B7T7_ARATH | TYRDC | 381 | ||
A8MQJ1 | A8MQJ1_ARATH | TYRDC | 547 | ||
F4JM08 | F4JM08_ARATH | TYRDC | 538 | ||
F4JM09 | F4JM09_ARATH | TYRDC | 547 |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL049917 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AL161573 EMBL· GenBank· DDBJ | CAB81456.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002687 EMBL· GenBank· DDBJ | AEE85522.1 EMBL· GenBank· DDBJ | Genomic DNA |