Q9LZY0 · MA654_ARATH
- Protein65-kDa microtubule-associated protein 4
- GeneMAP65-4
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids677 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Microtubule-associated protein involved in mitotic spindle formation.
Features
Showing features for site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 406 | Microtubule binding | ||||
Sequence: A | ||||||
Site | 417 | Microtubule binding | ||||
Sequence: A |
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | microtubule | |
Cellular Component | nucleus | |
Cellular Component | spindle | |
Cellular Component | spindle pole | |
Molecular Function | microtubule binding | |
Biological Process | cell division | |
Biological Process | microtubule cytoskeleton organization |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended name65-kDa microtubule-associated protein 4
- Short namesAtMAP65-4
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9LZY0
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Note: Localized specifically to MT that rearranged to form a spindle and the polar sides of the spindle proper. Associates to MT in preprophase band, during anaphase, and in phragmoplast.
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000395475 | 1-677 | 65-kDa microtubule-associated protein 4 | |||
Sequence: MIRNSTEQFSRIETTCGLLLRQLQEIWNEMGETEDEKDASLADIEKECLSVYKRKVEEASRGKANLLKEIAVGRAEIAAIGSSMGGQEIHSNSRLGENLKEELENVNVQLDGLRKRKAERMIRFNEVIDQLLKLSLQLGNPTDYLKKFAAEETDLSLQRLEELRSQLGELQNEKSKRLEEVECLLKTLNSLCSVLGEDFKGMIRGIHSSLVDSNTRDVSRSTLDKLDMMIVNLREAKLQRMQKVQDLAVSLLELWNLLDTPAEEQKIFHNVTCSIALTESEITEANILSVASIKRVEDEVIRLSKIKITKIKEVILRKRLELEEISRKMHMATEVLKSENFSVEAIESGVKDPEQLLEQIDSEIAKVKEEASSRKEILEKVEKWMSACEEESWLEEYNRDDNRYNAGRGAHLTLKRAEKARLLVNKLPGMVEALTAKVTAWENERGNEFLYDGVRVLSMLGQYKTVWEEKEHEKQRQRDMKKLHGQLITEQEALYGSKPSPNKSGKKPLRTPVNAAMNRKLSLGGAMLHQSLKHEKATLNSKRTKYYDQNATSRRDSALPTLSGRRNSELPGRIRSKNVPVAGKAARSPMLRKPLSPVTSNILNSPEDHHKDAYTTKERILTPKTNEEKKRAVPTTPAASVAMTEATTPFTPAVEKRMDEEDVIVEYSFEEVRAGFC | ||||||
Modified residue | 500 | Phosphoserine | ||||
Sequence: S |
Keywords
- PTM
Proteomic databases
Expression
Induction
Cell cycle-regulated expression with higher levels during mitosis.
Gene expression databases
Interaction
Subunit
Forms a dimer (By similarity).
Binds to microtubules (MT). Bundles polymerized MT via the formation of 25-nm crossbridges with centrally located endocytic MT
Binds to microtubules (MT). Bundles polymerized MT via the formation of 25-nm crossbridges with centrally located endocytic MT
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for coiled coil, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Coiled coil | 49-121 | |||||
Sequence: LSVYKRKVEEASRGKANLLKEIAVGRAEIAAIGSSMGGQEIHSNSRLGENLKEELENVNVQLDGLRKRKAERM | ||||||
Coiled coil | 151-189 | |||||
Sequence: EETDLSLQRLEELRSQLGELQNEKSKRLEEVECLLKTLN | ||||||
Coiled coil | 354-383 | |||||
Sequence: EQLLEQIDSEIAKVKEEASSRKEILEKVEK | ||||||
Region | 491-511 | Disordered | ||||
Sequence: QEALYGSKPSPNKSGKKPLRT | ||||||
Compositional bias | 548-564 | Polar residues | ||||
Sequence: DQNATSRRDSALPTLSG | ||||||
Region | 548-572 | Disordered | ||||
Sequence: DQNATSRRDSALPTLSGRRNSELPG | ||||||
Region | 592-640 | Disordered | ||||
Sequence: RKPLSPVTSNILNSPEDHHKDAYTTKERILTPKTNEEKKRAVPTTPAAS | ||||||
Compositional bias | 605-631 | Basic and acidic residues | ||||
Sequence: SPEDHHKDAYTTKERILTPKTNEEKKR |
Sequence similarities
Belongs to the MAP65/ASE1 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length677
- Mass (Da)76,939
- Last updated2010-07-13 v2
- Checksum26F8747DA32AD036
Sequence caution
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 548-564 | Polar residues | ||||
Sequence: DQNATSRRDSALPTLSG | ||||||
Compositional bias | 605-631 | Basic and acidic residues | ||||
Sequence: SPEDHHKDAYTTKERILTPKTNEEKKR |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL162295 EMBL· GenBank· DDBJ | CAB82688.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002686 EMBL· GenBank· DDBJ | AEE80116.2 EMBL· GenBank· DDBJ | Genomic DNA |