Q9LYD9 · EMF1_ARATH

Function

function

Transcription repressor that regulates phase transition during shoot, flower and seeds development. Controls leaves development, shoot architecture and flowering by delaying both the vegetative to reproductive transition and flower initiation. Participates in polycomb group (PcG) protein complex-mediated (including EMF2) silencing of the flower homeotic genes AGAMOUS (AG), PISTILLATA (PI), and APETALA3 (AP3), as well as of some regulatory genes such as ABSCISIC ACID INSENSITIVE3 (ABI3), LONG VEGETATIVE PHASE1 (LOV1), and FLOWERING LOCUS C (FLC) during vegetative development. Required for histone methylation or for maintaining a stable histone methylation (e.g. H3K27me3) pattern of repressed target genes (including genes involved in salt stress response and flower development); this repression is counteracted by ULT1 (PubMed:23632855).
Can bind non specifically DNA (both double- and single-stranded) and RNA

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular Functiondouble-stranded DNA binding
Molecular FunctionRNA binding
Molecular Functionsingle-stranded DNA binding
Biological Processepigenetic regulation of gene expression
Biological Processhyperosmotic salinity response
Biological Processmeristem determinacy
Biological Processnegative regulation of DNA-templated transcription
Biological Processnegative regulation of flower development
Biological Processnegative regulation of gene expression, epigenetic
Biological Processpost-embryonic development
Biological Processregulation of flower development
Biological Processregulation of response to salt stress
Biological Processshoot system development

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Protein EMBRYONIC FLOWER 1

Gene names

    • Name
      EMF1
    • ORF names
      F15N18.120
    • Ordered locus names
      At5g11530

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9LYD9
  • Secondary accessions
    • A5YY84

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Nucleus
Note: Follow a speckle-like pattern.

Keywords

Phenotypes & Variants

Disruption phenotype

Abolished rosette shoot development, reduced inflorescence with several flowers lacking petals, and differentiation of the apical meristem from indeterminate to determinate growth by producing a single terminal flower on all nodes. Altered inflorescence-to-flower transition. Degenerated flowers with only carpelloid structures capped with stigmatic papillae but lacking leaves, petals and stamen. Derepressed seed development program. Decreased H3K27me3 marks but increased H3K4me3 marks on target gene loci (PubMed:23632855).
Plants missing both EMF1 and ULT1 have rescued normal H3K27me3 marks and H3K4me3 marks (PubMed:23632855).

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 65 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004054091-1096Protein EMBRYONIC FLOWER 1

Proteomic databases

Expression

Tissue specificity

Expressed in mature embryo, root tips, cotyledons, leaves, stems, shoot apex, and flower clusters, with highest levels in flowers. The presence in the shoot apical meristem (SAM) is required to maintain vegetative development and prevent early flowering.

Developmental stage

After flowering, expressed in the stigma and anthers.

Gene expression databases

Interaction

Subunit

Interacts with MSI1.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, motif.

Type
IDPosition(s)Description
Region155-189Disordered
Compositional bias168-182Polar residues
Motif170-177Nuclear localization signal 1
Region274-296Disordered
Motif281-288Nuclear localization signal 2
Compositional bias315-339Polar residues
Region315-348Disordered
Region337-617DNA-binding
Region366-420Disordered
Compositional bias384-400Polar residues
Region563-612Disordered
Compositional bias569-605Basic and acidic residues
Region629-651Disordered
Region866-1096DNA-binding
Region1007-1032Disordered
Compositional bias1018-1032Polar residues
Region1070-1096Disordered
Motif1071-1078Nuclear localization signal 3

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,096
  • Mass (Da)
    121,671
  • Last updated
    2000-10-01 v1
  • Checksum
    190308C7A96A0F61
MGSSIKINSISIDLAGAANEIDMVKCDHFSMRGFVAETRERDLRKCWPFSEESVSLVDQQSYTLPTLSVPKFRWWHCMSCIKDIDAHGPKDCGLHSNSKAIGNSSVIESKSKFNSLTIIDHEKEKKTDIADNAIEEKVGVNCENDDQTATTFLKKARGRPMGASNVRSKSRKLVSPEQVGNNRSKEKLNKPSMDISSWKEKQNVDQAVTTFGSSEIAGVVEDTPPKATKNHKGIRGLMECDNGSSESINLAMSGLQRRKSRKVRLLSELLGNTKTSGGSNIRKEESALKKESVRGRKRKLLPENNYVSRILSTMGATSENASKSCDSDQGNSESTDSGFDRTPFKGKQRNRRFQVVDEFVPSLPCETSQEGIKEHDADPSKRSTPAHSLFTGNDSVPCPPGTQRTERKLSLPKKKTKKPVIDNGKSTVISFSNGIDGSQVNSHTGPSMNTVSQTRDLLNGKRVGGLFDNRLASDGYFRKYLSQVNDKPITSLHLQDNDYVRSRDAEPNCLRDFSSSSKSSSGGWLRTGVDIVDFRNNNHNTNRSSFSNLKLRYPPSSTEVADLSRVLQKDASGADRKGKTVMVQEHHGAPRSQSHDRKETTTEEQNNDDIPMEIVELMAKNQYERCLPDKEEDVSNKQPSQETAHKSKNALLIDLNETYDNGISLEDNNTSRPPKPCSSNARREEHFPMGRQQNSHDFFPISQPYVPSPFGIFPPTQENRASSIRFSGHNCQWLGNLPTVGNQNPSPSSFRVLRACDTCQSVPNQYREASHPIWPSSMIPPQSQYKPVSLNINQSTNPGTLSQASNNENTWNLNFVAANGKQKCGPNPEFSFGCKHAAGVSSSSSRPIDNFSSESSIPALHLLSLLDPRLRSTTPADQHGNTKFTKRHFPPANQSKEFIELQTGDSSKSAYSTKQIPFDLYSKRFTQEPSRKSFPITPPIGTSSLSFQNASWSPHHQEKKTKRKDTFAPVYNTHEKPVFASSNDQAKFQLLGASNSMMLPLKFHMTDKEKKQKRKAESCNNNASAGPVKNSSGPIVCSVNRNPADFTIPEPGNVYMLTGEHLKVRKRTTFKKKPAVCKQDAMKQTKKPVCPPTQNA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias168-182Polar residues
Compositional bias315-339Polar residues
Compositional bias384-400Polar residues
Compositional bias569-605Basic and acidic residues
Compositional bias1018-1032Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF319968
EMBL· GenBank· DDBJ
AAK98528.1
EMBL· GenBank· DDBJ
Genomic DNA
AL163815
EMBL· GenBank· DDBJ
CAB87713.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED91692.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
ANM68488.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
ANM68489.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598316
EMBL· GenBank· DDBJ
ABR08848.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598317
EMBL· GenBank· DDBJ
ABR08849.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598318
EMBL· GenBank· DDBJ
ABR08850.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598319
EMBL· GenBank· DDBJ
ABR08851.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598320
EMBL· GenBank· DDBJ
ABR08852.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598321
EMBL· GenBank· DDBJ
ABR08853.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598322
EMBL· GenBank· DDBJ
ABR08854.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598323
EMBL· GenBank· DDBJ
ABR08855.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598324
EMBL· GenBank· DDBJ
ABR08856.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598325
EMBL· GenBank· DDBJ
ABR08857.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598326
EMBL· GenBank· DDBJ
ABR08858.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598327
EMBL· GenBank· DDBJ
ABR08859.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598328
EMBL· GenBank· DDBJ
ABR08860.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598329
EMBL· GenBank· DDBJ
ABR08861.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598330
EMBL· GenBank· DDBJ
ABR08862.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598331
EMBL· GenBank· DDBJ
ABR08863.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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