Q9LVZ7 · PDCT1_ARATH
- ProteinPhosphatidylcholine:diacylglycerol cholinephosphotransferase 1
- GeneROD1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids301 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Functions as a phosphatidylcholine:diacylglycerol cholinephosphotransferase that catalyzes the transfer of the phosphocholine headgroup from phosphatidylcholine (PC) to diacylglycerol, a major reaction for the transfer of 18:1 into phosphatidylcholine for desaturation and also for the reverse transfer of 18:2 and 18:3 into the triacylglycerols synthesis pathway.
Catalytic activity
- 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-ditetradecanoyl-sn-glycerol + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineThis reaction proceeds in the forward direction.
Kinetics
Vmax | pH | TEMPERATURE[C] | NOTES | EVIDENCE | |
---|---|---|---|---|---|
4.5 nmol/min/mg | 23 | with phosphatidylcholine as substrate |
pH Dependence
Optimum pH is 6.5-7 at 23 degrees Celsius.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 216 | ||||
Active site | 256 | ||||
Active site | 260 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | diacylglycerol cholinephosphotransferase activity | |
Biological Process | phosphatidylcholine metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Chemistry
Names & Taxonomy
Protein names
- Recommended namePhosphatidylcholine:diacylglycerol cholinephosphotransferase 1
- EC number
- Short namesAtPDCT1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9LVZ7
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 88-108 | Helical | |||
Transmembrane | 141-161 | Helical | |||
Transmembrane | 171-191 | Helical | |||
Transmembrane | 202-222 | Helical | |||
Transmembrane | 255-275 | Helical | |||
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Reduction of 18:2 and 18:3 triacylglycerols (TAG) accumulation in seeds by 40 percent.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 16 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000425110 | 1-301 | Phosphatidylcholine:diacylglycerol cholinephosphotransferase 1 | ||
Proteomic databases
PTM databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-39 | Disordered | |||
Compositional bias | 11-39 | Polar residues | |||
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length301
- Mass (Da)32,977
- Last updated2000-10-01 v1
- Checksum4423EA943357E0DF
Sequence caution
Features
Showing features for sequence conflict, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Sequence conflict | 1 | in Ref. 3; AAK49592 | |||
Compositional bias | 11-39 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB017071 EMBL· GenBank· DDBJ | BAB02313.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002686 EMBL· GenBank· DDBJ | AEE75730.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF372876 EMBL· GenBank· DDBJ | AAK49592.1 EMBL· GenBank· DDBJ | mRNA | Different initiation | |
BT004552 EMBL· GenBank· DDBJ | AAO42798.1 EMBL· GenBank· DDBJ | mRNA | ||
AY086160 EMBL· GenBank· DDBJ | AAM63365.1 EMBL· GenBank· DDBJ | mRNA |