Q9LTW5 · AGC15_ARATH
- ProteinSerine/threonine-protein kinase AGC1-5
- GeneAGC1-5
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids577 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Functions redudantly with AGC1-7 as signaling component in the pollen tube. Required for polarized growth of pollen tubes.
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Activity regulation
Activated by PDPK1/PDK1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 191-199 | ATP (UniProtKB | ChEBI) | |||
Binding site | 214 | ATP (UniProtKB | ChEBI) | |||
Active site | 310 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | histone H2AS1 kinase activity | |
Molecular Function | kinase activity | |
Molecular Function | protein serine kinase activity | |
Biological Process | pollen tube growth | |
Biological Process | protein phosphorylation | |
Biological Process | unidimensional cell growth |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein kinase AGC1-5
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9LTW5
Proteomes
Organism-specific databases
Genome annotation databases
Phenotypes & Variants
Disruption phenotype
No visible phenotype under normal growth conditions, but pollen of the double mutants agc1.5 and agc1.7 is impaired in polarized growth of pollen tube.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 35 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000431358 | 1-577 | Serine/threonine-protein kinase AGC1-5 | ||
Post-translational modification
Autophosphorylated and phosphorylated by PDPK1/PDK1.
Proteomic databases
PTM databases
Expression
Interaction
Subunit
Interacts with PDPK1/PDK1.
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | IntAct | |
---|---|---|---|---|---|
BINARY | Q9LTW5 | PDPK1 Q9XF67 | 3 | EBI-1103747, EBI-1103587 |
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-151 | Disordered | |||
Compositional bias | 42-57 | Basic and acidic residues | |||
Compositional bias | 67-89 | Polar residues | |||
Domain | 185-509 | Protein kinase | |||
Domain | 510-577 | AGC-kinase C-terminal | |||
Sequence similarities
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length577
- Mass (Da)63,768
- Last updated2000-10-01 v1
- Checksum2CD2C7C30FAFA9A2
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 42-57 | Basic and acidic residues | |||
Compositional bias | 67-89 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB024033 EMBL· GenBank· DDBJ | BAB02413.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002686 EMBL· GenBank· DDBJ | AEE75233.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002686 EMBL· GenBank· DDBJ | AEE75234.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002686 EMBL· GenBank· DDBJ | AEE75235.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT011689 EMBL· GenBank· DDBJ | AAS49052.1 EMBL· GenBank· DDBJ | mRNA | ||
BT020332 EMBL· GenBank· DDBJ | AAV85687.1 EMBL· GenBank· DDBJ | mRNA | ||
AK229198 EMBL· GenBank· DDBJ | BAF01068.1 EMBL· GenBank· DDBJ | mRNA |