Q9LSR9 · LRK18_ARATH
- ProteinL-type lectin-domain containing receptor kinase I.8
- GeneLECRK18
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids657 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Variants
Variant ID(s) | Position(s) | Change | Description | Clinical significance | Provenance | ||
---|---|---|---|---|---|---|---|
tmp_5_24260588_G_A | 9 | W>* | 1000Genomes | ||||
Consequence: stop gained Somatic: No Accession: 5:g.24260588G>A Codon: TGG/TAG Consequence type: stop gained Cytogenetic band: Genomic location: 5:g.24260588G>A Locations: - p.Trp9Ter (EnsemblPlants:AT5G60280.1) - c.26G>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24260635_G_A | 25 | E>K | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.1) Somatic: No Accession: 5:g.24260635G>A Codon: GAA/AAA Consequence type: missense Cytogenetic band: Genomic location: 5:g.24260635G>A Locations: - p.Glu25Lys (EnsemblPlants:AT5G60280.1) - c.73G>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24260656_G_A | 32 | G>S | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.04) Somatic: No Accession: 5:g.24260656G>A Codon: GGT/AGT Consequence type: missense Cytogenetic band: Genomic location: 5:g.24260656G>A Locations: - p.Gly32Ser (EnsemblPlants:AT5G60280.1) - c.94G>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24260680_G_C | 40 | V>L | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: 5:g.24260680G>C Codon: GTT/CTT Consequence type: missense Cytogenetic band: Genomic location: 5:g.24260680G>C Locations: - p.Val40Leu (EnsemblPlants:AT5G60280.1) - c.118G>C (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24260701_C_G | 47 | L>V | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.25) Somatic: No Accession: 5:g.24260701C>G Codon: CTT/GTT Consequence type: missense Cytogenetic band: Genomic location: 5:g.24260701C>G Locations: - p.Leu47Val (EnsemblPlants:AT5G60280.1) - c.139C>G (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24260824_G_A | 88 | A>T | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: 5:g.24260824G>A Codon: GCT/ACT Consequence type: missense Cytogenetic band: Genomic location: 5:g.24260824G>A Locations: - p.Ala88Thr (EnsemblPlants:AT5G60280.1) - c.262G>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24260866_G_T | 102 | A>S | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 5:g.24260866G>T Codon: GCT/TCT Consequence type: missense Cytogenetic band: Genomic location: 5:g.24260866G>T Locations: - p.Ala102Ser (EnsemblPlants:AT5G60280.1) - c.304G>T (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24261088_G_A | 176 | D>N | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.3) Somatic: No Accession: 5:g.24261088G>A Codon: GAC/AAC Consequence type: missense Cytogenetic band: Genomic location: 5:g.24261088G>A Locations: - p.Asp176Asn (EnsemblPlants:AT5G60280.1) - c.526G>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH07454714 | 180 | L>F | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.1) Somatic: No Accession: 5:g.24261100C>T Codon: CTC/TTC Consequence type: missense Cytogenetic band: Genomic location: 5:g.24261100C>T Locations: - p.Leu180Phe (EnsemblPlants:AT5G60280.1) - c.538C>T (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24261161_G_C | 200 | G>A | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.07) Somatic: No Accession: 5:g.24261161G>C Codon: GGA/GCA Consequence type: missense Cytogenetic band: Genomic location: 5:g.24261161G>C Locations: - p.Gly200Ala (EnsemblPlants:AT5G60280.1) - c.599G>C (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24261164_C_T | 201 | T>I | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.11) Somatic: No Accession: 5:g.24261164C>T Codon: ACT/ATT Consequence type: missense Cytogenetic band: Genomic location: 5:g.24261164C>T Locations: - p.Thr201Ile (EnsemblPlants:AT5G60280.1) - c.602C>T (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH07454715 | 205 | V>A | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 5:g.24261176T>C Codon: GTT/GCT Consequence type: missense Cytogenetic band: Genomic location: 5:g.24261176T>C Locations: - p.Val205Ala (EnsemblPlants:AT5G60280.1) - c.614T>C (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24261233_T_A | 224 | M>K | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.23) Somatic: No Accession: 5:g.24261233T>A Codon: ATG/AAG Consequence type: missense Cytogenetic band: Genomic location: 5:g.24261233T>A Locations: - p.Met224Lys (EnsemblPlants:AT5G60280.1) - c.671T>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24261269_T_C | 236 | V>A | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: 5:g.24261269T>C Codon: GTC/GCC Consequence type: missense Cytogenetic band: Genomic location: 5:g.24261269T>C Locations: - p.Val236Ala (EnsemblPlants:AT5G60280.1) - c.707T>C (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24261326_G_C | 255 | S>T | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: 5:g.24261326G>C Codon: AGT/ACT Consequence type: missense Cytogenetic band: Genomic location: 5:g.24261326G>C Locations: - p.Ser255Thr (EnsemblPlants:AT5G60280.1) - c.764G>C (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH07454716 | 337 | K>R | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.06) Somatic: No Accession: 5:g.24261572A>G Codon: AAA/AGA Consequence type: missense Cytogenetic band: Genomic location: 5:g.24261572A>G Locations: - p.Lys337Arg (EnsemblPlants:AT5G60280.1) - c.1010A>G (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24261737_G_A | 392 | R>K | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.07) Somatic: No Accession: 5:g.24261737G>A Codon: AGG/AAG Consequence type: missense Cytogenetic band: Genomic location: 5:g.24261737G>A Locations: - p.Arg392Lys (EnsemblPlants:AT5G60280.1) - c.1175G>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH14642220 | 464 | K>N | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 5:g.24261954A>C Codon: AAA/AAC Consequence type: missense Cytogenetic band: Genomic location: 5:g.24261954A>C Locations: - p.Lys464Asn (EnsemblPlants:AT5G60280.1) - c.1392A>C (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24261988_G_C | 476 | G>R | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: 5:g.24261988G>C Codon: GGA/CGA Consequence type: missense Cytogenetic band: Genomic location: 5:g.24261988G>C Locations: - p.Gly476Arg (EnsemblPlants:AT5G60280.1) - c.1426G>C (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH03457285 | 480 | D>N | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 5:g.24262000G>A Codon: GAT/AAT Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262000G>A Locations: - p.Asp480Asn (EnsemblPlants:AT5G60280.1) - c.1438G>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH07454719 | 494 | T>K | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.12) Somatic: No Accession: 5:g.24262043C>A Codon: ACA/AAA Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262043C>A Locations: - p.Thr494Lys (EnsemblPlants:AT5G60280.1) - c.1481C>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH03457286 | 506 | G>A | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: 5:g.24262079G>C Codon: GGA/GCA Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262079G>C Locations: - p.Gly506Ala (EnsemblPlants:AT5G60280.1) - c.1517G>C (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24262109_C_T | 516 | T>I | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 5:g.24262109C>T Codon: ACT/ATT Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262109C>T Locations: - p.Thr516Ile (EnsemblPlants:AT5G60280.1) - c.1547C>T (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH12873150 | 525 | A>S | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.02) Somatic: No Accession: 5:g.24262135G>T Codon: GCA/TCA Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262135G>T Locations: - p.Ala525Ser (EnsemblPlants:AT5G60280.1) - c.1573G>T (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH12873151 | 531 | T>I | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.05) Somatic: No Accession: 5:g.24262154C>T Codon: ACT/ATT Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262154C>T Locations: - p.Thr531Ile (EnsemblPlants:AT5G60280.1) - c.1592C>T (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24262195_A_C | 545 | K>Q | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.48) Somatic: No Accession: 5:g.24262195A>C Codon: AAA/CAA Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262195A>C Locations: - p.Lys545Gln (EnsemblPlants:AT5G60280.1) - c.1633A>C (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH12873152 | 551 | W>R | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.02) Somatic: No Accession: 5:g.24262213T>A Codon: TGG/AGG Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262213T>A Locations: - p.Trp551Arg (EnsemblPlants:AT5G60280.1) - c.1651T>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH12873153 | 558 | R>K | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.81) Somatic: No Accession: 5:g.24262235G>A Codon: AGG/AAG Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262235G>A Locations: - p.Arg558Lys (EnsemblPlants:AT5G60280.1) - c.1673G>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH14642221 | 562 | I>F | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: 5:g.24262246A>T Codon: ATC/TTC Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262246A>T Locations: - p.Ile562Phe (EnsemblPlants:AT5G60280.1) - c.1684A>T (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH00744649 | 574 | I>R | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.05) Somatic: No Accession: 5:g.24262283T>G Codon: ATA/AGA Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262283T>G Locations: - p.Ile574Arg (EnsemblPlants:AT5G60280.1) - c.1721T>G (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24262300_G_T | 580 | V>L | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.02) Somatic: No Accession: 5:g.24262300G>T Codon: GTA/TTA Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262300G>T Locations: - p.Val580Leu (EnsemblPlants:AT5G60280.1) - c.1738G>T (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24262356_G_A | 598 | M>I | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.04) Somatic: No Accession: 5:g.24262356G>A Codon: ATG/ATA Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262356G>A Locations: - p.Met598Ile (EnsemblPlants:AT5G60280.1) - c.1794G>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH07454720 | 607 | R>G | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: 5:g.24262381A>G Codon: AGA/GGA Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262381A>G Locations: - p.Arg607Gly (EnsemblPlants:AT5G60280.1) - c.1819A>G (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH03457288 | 613 | D>N | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.04) Somatic: No Accession: 5:g.24262399G>A Codon: GAT/AAT Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262399G>A Locations: - p.Asp613Asn (EnsemblPlants:AT5G60280.1) - c.1837G>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24262427_G_A | 622 | G>E | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.02) Somatic: No Accession: 5:g.24262427G>A Codon: GGG/GAG Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262427G>A Locations: - p.Gly622Glu (EnsemblPlants:AT5G60280.1) - c.1865G>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH12873154 | 624 | V>I | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.34) Somatic: No Accession: 5:g.24262432G>A Codon: GTT/ATT Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262432G>A Locations: - p.Val624Ile (EnsemblPlants:AT5G60280.1) - c.1870G>A (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
tmp_5_24262438_C_T | 626 | P>S | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.31) Somatic: No Accession: 5:g.24262438C>T Codon: CCG/TCG Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262438C>T Locations: - p.Pro626Ser (EnsemblPlants:AT5G60280.1) - c.1876C>T (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: | |||||||
ENSVATH07454721 | 651 | I>F | 1000Genomes | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: 5:g.24262513A>T Codon: ATT/TTT Consequence type: missense Cytogenetic band: Genomic location: 5:g.24262513A>T Locations: - p.Ile651Phe (EnsemblPlants:AT5G60280.1) - c.1951A>T (EnsemblPlants:AT5G60280.1) Source type: large scale study Cross-references: |