Q9LSR9 · LRK18_ARATH
- ProteinL-type lectin-domain containing receptor kinase I.8
- GeneLECRK18
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids657 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
Involved in resistance response to the pathogenic fungus Alternaria brassicicola.
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | carbohydrate binding | |
Molecular Function | kinase activity | |
Molecular Function | NAD+ binding | |
Molecular Function | protein serine kinase activity | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | defense response to fungus | |
Biological Process | protein autophosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameL-type lectin-domain containing receptor kinase I.8
- EC number
- Short namesLecRK-I.8
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9LSR9
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass type I membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 24-282 | Extracellular | ||||
Sequence: QETGFSFNGFRQGDLHVDGVAQILPGGLLRLTDTSEQKKGHAFFRQPLVFNSSEPLSFSTHFVCAMVRKPGVTGGNGIAFFLSPSMDLTNADATQYLGLFNTTTNRSPSSHIFAIELDTVQSAEFDDIDNNHVGIDVNSLTSVESAPASYFSDKKGLNKSISLLSGDSIQVWVDFDGTVLNVSLAPLGIRKPSQSLISRSMNLSEVIQDRMFVGFSAATGQLANNHYILGWSFSRSKASLQSLDISKLPQVPHPKMKTS | ||||||
Transmembrane | 283-303 | Helical | ||||
Sequence: LLLILLLIVLGIILLVLLVGA | ||||||
Topological domain | 304-657 | Cytoplasmic | ||||
Sequence: YLYRRNKYAEVREEWEKEYGPHRYSYKSLYKATKGFHKDGFLGKGGFGEVYKGTLPQEDIAVKRFSHHGERGMKQFVAEIASMGCLDHRNLVPLFGYCRRKGEFLLVSKYMPNGSLDQFLFHNREPSLTWSKRLGILKGIASALKYLHTEATQVVLHRDIKASNVMLDTDFTGKLGDFGMARFHDHGANPTTTGAVGTVGYMGPELTSMGASTKTDVYAFGALILEVTCGRRPVEPNLPIEKQLLVKWVCDCWKRKDLISARDPKLSGELIPQIEMVLKLGLLCTNLVPESRPDMVKVVQYLDRQVSLPDFSPDSPGIGIVTPVLVGGSSTVISNISSPVTEFITHSIQYGIGR |
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Increased susceptibility to the fungus Alternaria brassicicola.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 38 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for signal, chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-23 | |||||
Sequence: MAPGLDLIWMVISFLLLIHLSSQ | ||||||
Chain | PRO_0000403077 | 24-657 | L-type lectin-domain containing receptor kinase I.8 | |||
Sequence: QETGFSFNGFRQGDLHVDGVAQILPGGLLRLTDTSEQKKGHAFFRQPLVFNSSEPLSFSTHFVCAMVRKPGVTGGNGIAFFLSPSMDLTNADATQYLGLFNTTTNRSPSSHIFAIELDTVQSAEFDDIDNNHVGIDVNSLTSVESAPASYFSDKKGLNKSISLLSGDSIQVWVDFDGTVLNVSLAPLGIRKPSQSLISRSMNLSEVIQDRMFVGFSAATGQLANNHYILGWSFSRSKASLQSLDISKLPQVPHPKMKTSLLLILLLIVLGIILLVLLVGAYLYRRNKYAEVREEWEKEYGPHRYSYKSLYKATKGFHKDGFLGKGGFGEVYKGTLPQEDIAVKRFSHHGERGMKQFVAEIASMGCLDHRNLVPLFGYCRRKGEFLLVSKYMPNGSLDQFLFHNREPSLTWSKRLGILKGIASALKYLHTEATQVVLHRDIKASNVMLDTDFTGKLGDFGMARFHDHGANPTTTGAVGTVGYMGPELTSMGASTKTDVYAFGALILEVTCGRRPVEPNLPIEKQLLVKWVCDCWKRKDLISARDPKLSGELIPQIEMVLKLGLLCTNLVPESRPDMVKVVQYLDRQVSLPDFSPDSPGIGIVTPVLVGGSSTVISNISSPVTEFITHSIQYGIGR | ||||||
Glycosylation | 74 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 124 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 181 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 204 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 225 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 25-257 | Legume-lectin like | ||||
Sequence: ETGFSFNGFRQGDLHVDGVAQILPGGLLRLTDTSEQKKGHAFFRQPLVFNSSEPLSFSTHFVCAMVRKPGVTGGNGIAFFLSPSMDLTNADATQYLGLFNTTTNRSPSSHIFAIELDTVQSAEFDDIDNNHVGIDVNSLTSVESAPASYFSDKKGLNKSISLLSGDSIQVWVDFDGTVLNVSLAPLGIRKPSQSLISRSMNLSEVIQDRMFVGFSAATGQLANNHYILGWSFS | ||||||
Domain | 339-611 | Protein kinase | ||||
Sequence: FHKDGFLGKGGFGEVYKGTLPQEDIAVKRFSHHGERGMKQFVAEIASMGCLDHRNLVPLFGYCRRKGEFLLVSKYMPNGSLDQFLFHNREPSLTWSKRLGILKGIASALKYLHTEATQVVLHRDIKASNVMLDTDFTGKLGDFGMARFHDHGANPTTTGAVGTVGYMGPELTSMGASTKTDVYAFGALILEVTCGRRPVEPNLPIEKQLLVKWVCDCWKRKDLISARDPKLSGELIPQIEMVLKLGLLCTNLVPESRPDMVKVVQYLDRQVSL |
Sequence similarities
In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
In the N-terminal section; belongs to the leguminous lectin family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length657
- Mass (Da)72,388
- Last updated2000-10-01 v1
- Checksum25760B35FD906E92
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB026632 EMBL· GenBank· DDBJ | BAA97508.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002688 EMBL· GenBank· DDBJ | AED97302.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT010577 EMBL· GenBank· DDBJ | AAQ65200.1 EMBL· GenBank· DDBJ | mRNA | ||
AK221799 EMBL· GenBank· DDBJ | BAD93956.1 EMBL· GenBank· DDBJ | mRNA |