Q9LRM7 · NCED6_ARATH
- Protein9-cis-epoxycarotenoid dioxygenase NCED6, chloroplastic
- GeneNCED6
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids577 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid biosynthesis from carotenoids. Contributes probably to abscisic acid synthesis for the induction of seed dormancy.
Catalytic activity
- a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal
Cofactor
Note: Binds 1 Fe2+ ion per subunit.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast stroma | |
Cellular Component | chloroplast thylakoid membrane | |
Molecular Function | 9-cis-epoxycarotenoid dioxygenase activity | |
Molecular Function | metal ion binding | |
Biological Process | abscisic acid biosynthetic process | |
Biological Process | response to red light | |
Biological Process | response to red or far red light |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name9-cis-epoxycarotenoid dioxygenase NCED6, chloroplastic
- EC number
- Short namesAtNCED6
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ9LRM7
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Note: Partially bound to the thylakoid.
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Plants exhibit abscisic-acid-deficient phenotypes in seeds, but not in vegetative tissues.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 67 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain, transit peptide.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000285995 | ?-577 | 9-cis-epoxycarotenoid dioxygenase NCED6, chloroplastic | |||
Sequence: MQHSLRSDLLPTKTSPRSHLLPQPKNANISRRILINPFKIPTLPDLTSPVPSPVKLKPTYPNLNLLQKLAATMLDKIESSIVIPMEQNRPLPKPTDPAVQLSGNFAPVNECPVQNGLEVVGQIPSCLKGVYIRNGANPMFPPLAGHHLFDGDGMIHAVSIGFDNQVSYSCRYTKTNRLVQETALGRSVFPKPIGELHGHSGLARLALFTARAGIGLVDGTRGMGVANAGVVFFNGRLLAMSEDDLPYQVKIDGQGDLETIGRFGFDDQIDSSVIAHPKVDATTGDLHTLSYNVLKKPHLRYLKFNTCGKKTRDVEITLPEPTMIHDFAITENFVVIPDQQMVFKLSEMIRGGSPVIYVKEKMARFGVLSKQDLTGSDINWVDVPDCFCFHLWNAWEERTEEGDPVIVVIGSCMSPPDTIFSESGEPTRVELSEIRLNMRTKESNRKVIVTGVNLEAGHINRSYVGRKSQFVYIAIADPWPKCSGIAKVDIQNGTVSEFNYGPSRFGGEPCFVPEGEGEEDKGYVMGFVRDEEKDESEFVVVDATDMKQVAAVRLPERVPYGFHGTFVSENQLKEQVF | ||||||
Transit peptide | 1-? | Chloroplast |
Proteomic databases
PTM databases
Expression
Tissue specificity
Expressed before fertilization in male and female gametophytes, and then immediately after pollination, restricted to seed endosperm.
Induction
Low induction by drought stress.
Developmental stage
Expressed in seeds at early and mid-maturation stages.
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-25 | Disordered | ||||
Sequence: MQHSLRSDLLPTKTSPRSHLLPQPK |
Sequence similarities
Belongs to the carotenoid oxygenase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length577
- Mass (Da)63,821
- Last updated2000-10-01 v1
- Checksum515E0A1B321B4FE1
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB028621 EMBL· GenBank· DDBJ | BAB01363.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002686 EMBL· GenBank· DDBJ | AEE76875.1 EMBL· GenBank· DDBJ | Genomic DNA |