Q9LRM7 · NCED6_ARATH

Function

function

Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid biosynthesis from carotenoids. Contributes probably to abscisic acid synthesis for the induction of seed dormancy.

Catalytic activity

Cofactor

Fe2+ (UniProtKB | Rhea| CHEBI:29033 )

Note: Binds 1 Fe2+ ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site276Fe cation (UniProtKB | ChEBI)
Binding site325Fe cation (UniProtKB | ChEBI)
Binding site390Fe cation (UniProtKB | ChEBI)
Binding site563Fe cation (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentchloroplast stroma
Cellular Componentchloroplast thylakoid membrane
Molecular Function9-cis-epoxycarotenoid dioxygenase activity
Molecular Functionmetal ion binding
Biological Processabscisic acid biosynthetic process
Biological Processresponse to red light
Biological Processresponse to red or far red light

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    9-cis-epoxycarotenoid dioxygenase NCED6, chloroplastic
  • EC number
  • Short names
    AtNCED6

Gene names

    • Name
      NCED6
    • ORF names
      MUJ8.12
    • Ordered locus names
      At3g24220

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9LRM7

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

Plants exhibit abscisic-acid-deficient phenotypes in seeds, but not in vegetative tissues.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 67 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain, transit peptide.

TypeIDPosition(s)Description
ChainPRO_0000285995?-5779-cis-epoxycarotenoid dioxygenase NCED6, chloroplastic
Transit peptide1-?Chloroplast

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed before fertilization in male and female gametophytes, and then immediately after pollination, restricted to seed endosperm.

Induction

Low induction by drought stress.

Developmental stage

Expressed in seeds at early and mid-maturation stages.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-25Disordered

Sequence similarities

Belongs to the carotenoid oxygenase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    577
  • Mass (Da)
    63,821
  • Last updated
    2000-10-01 v1
  • Checksum
    515E0A1B321B4FE1
MQHSLRSDLLPTKTSPRSHLLPQPKNANISRRILINPFKIPTLPDLTSPVPSPVKLKPTYPNLNLLQKLAATMLDKIESSIVIPMEQNRPLPKPTDPAVQLSGNFAPVNECPVQNGLEVVGQIPSCLKGVYIRNGANPMFPPLAGHHLFDGDGMIHAVSIGFDNQVSYSCRYTKTNRLVQETALGRSVFPKPIGELHGHSGLARLALFTARAGIGLVDGTRGMGVANAGVVFFNGRLLAMSEDDLPYQVKIDGQGDLETIGRFGFDDQIDSSVIAHPKVDATTGDLHTLSYNVLKKPHLRYLKFNTCGKKTRDVEITLPEPTMIHDFAITENFVVIPDQQMVFKLSEMIRGGSPVIYVKEKMARFGVLSKQDLTGSDINWVDVPDCFCFHLWNAWEERTEEGDPVIVVIGSCMSPPDTIFSESGEPTRVELSEIRLNMRTKESNRKVIVTGVNLEAGHINRSYVGRKSQFVYIAIADPWPKCSGIAKVDIQNGTVSEFNYGPSRFGGEPCFVPEGEGEEDKGYVMGFVRDEEKDESEFVVVDATDMKQVAAVRLPERVPYGFHGTFVSENQLKEQVF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB028621
EMBL· GenBank· DDBJ
BAB01363.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002686
EMBL· GenBank· DDBJ
AEE76875.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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